BPC January 24 update

MediWound MDWD Phase 2 success; HCWB Phase 1 trial cleared

Pre-Market Updates

MediWound Ltd. (NASDAQ: MDWD) announced top-line results from its Phase 2 study of EscharEx to treat venous leg ulcers (VLUs). The study met its primary endpoint.

HCW Biologics Inc. (NASDAQ: HCWB) announced that the Masonic Cancer Center, University of Minnesota was cleared by the FDA to proceed to evaluate HCW9218, in a Phase 1 trial to treat advanced solid tumors with progressive disease after prior chemotherapies.

SVB Leerink maintained Gemini Therapeutics (NASDAQ: GMTX) with an Outperform rating and lowered the price target from $15 to $10.

Viking Therapeutics, Inc. (NASDAQ: VKTX) announced that its Phase 1b clinical trial of VK0214 to treat X-linked adrenoleukodystrophy (X-ALD) has been placed on clinical hold by FDA. The FDA has requested an additional preclinical study prior to continuing the Phase 1b study of VK0214 in X-ALD.

Revelation Biosciences Inc. (NASDAQ: REVB) entered into a private placement agreement with an institutional investor, to sell 1,293,126 shares of stock at $3.00 per share as well as warrants and pre-funded warrants. The gross proceeds will be approximately $7.76 million.

OPKO Health, Inc. (NASDAQ: OPK) and Pfizer Inc. (NYSE: PFE) announced that the FDA issued a Complete Response Letter (CRL) for the Biologics License Application (BLA) for somatrogon. Somatrogon is an investigational human growth hormone to treat growth hormone deficiency (GHD) in pediatric patients.

Lantern Pharma (NASDAQ: LTRN) announced that the FDA granted both Rare Pediatric Disease Designation (RPDD) and Orphan Drug Designation (ODD) for LP-184 for the treatment of pediatric patients with Atypical Teratoid Rhabdoid Tumor.

Pre-Market Advancers

CompanyPriceChange
ENDP
Endo International plc
$1.01 +1.01  +100%
ATHX
Athersys Inc.
$1.01 +1.01  +100%
FREQ
Frequency Therapeutics Inc.
$1.01 +1.01  +100%
EVFM
Evofem Biosciences Inc.
$1.01 +1.01  +100%
PTE
PolarityTE Inc.
$1.01 +1.01  +100%
ACRX
AcelRx Pharmaceuticals Inc.
$1.01 +1.01  +100%
IMMX
Immix Biopharma Inc.
$1.01 +1.01  +100%
HLVX
HilleVax Inc.
$1.01 +1.01  +100%
ATNF
180 Life Sciences Corp.
$1.01 +1.01  +100%
NVCT
Nuvectis Pharma Inc.
$1.01 +1.01  +100%

Pre-Market Decliners

CompanyPriceChange
GOVX
GeoVax Labs Inc.
$1.01 -1.01  -100%
FHTX
Foghorn Therapeutics Inc.
$1.01 -1.01  -100%
SIGA
SIGA Technologies Inc.
$1.01 -1.01  -100%
TXMD
TherapeuticsMD Inc.
$1.01 -1.01  -100%
NNVC
NanoViricides Inc.
$1.01 -1.01  -100%
TNYA
Tenaya Therapeutics Inc.
$1.01 -1.01  -100%
AEMD
Aethlon Medical Inc.
$1.01 -1.01  -100%
TPST
Tempest Therapeutics Inc.
$1.01 -1.01  -100%
IBIO
iBio Inc.
$1.01 -1.01  -100%
TNXP
Tonix Pharmaceuticals Holding Corp.
$1.01 -1.01  -100%