BPC January 11 update

Black Diamond BDTX IND cleared; Kiniksa KNSA Organ transplant drug

Pre-Market Updates

Notable JPM presentations for Tuesday, January 11, 2022: SWTX PTGX ALLO and KPTI

Black Diamond Therapeutics, Inc. (NASDAQ: BDTX) announced that the FDA cleared an investigational new drug (IND) application for BDTX-1535 to treat glioblastoma multiforme (GBM) and non-small cell lung cancer (NSCLC). A Phase 1 study of BDTX-1535 will be initiated in the first quarter of 2022 with a clinical update in the second half of 2023.

Kiniksa Pharmaceuticals, Ltd. (NASDAQ: KNSA) shares are trading up in the pre-market after doctors at the University of Maryland have transplanted a genetically modified pig heart into a human patient. The University of Maryland medical team used a drug developed by Kiniksa to prevent organ rejection.

Cellectis (NASDAQ: CLLS) stated that its licensed partner, Allogene Therapeutics, Inc. (NASDAQ: ALLO) announced that the FDA lifted the hold on its clinical trials. Allogene's allogeneic CAR-T programs utilize Cellectis' technologies.

Immunome, Inc. (NASDAQ: IMNM) announced that it received a clinical hold letter from the FDA in response to its investigational new drug (IND) application requesting further information related to the preparation and administration of IMM-BCP-01 at clinical sites.

Phio Pharmaceuticals Corp. (NASDAQ: PHIO) announced that it has received regulatory clearance to start a clinical trial with its lead product candidate, PH-762 to treat melanoma. Phio expects to dose the first patient in the first quarter of 2022.

Pre-Market Advancers

CompanyPriceChange
CGTX
Cognition Therapeutics Inc.
$4.30+0.8  +22.86%
HOOK
HOOKIPA Pharma Inc.
$1.79+0.29  +19.33%
MRKR
Marker Therapeutics Inc.
$0.71+0.11  +18.33%
IMMX
Immix Biopharma Inc.
$5.31+0.8  +17.74%
BSGM
BioSig Technologies Inc.
$2.10+0.3  +16.67%
CALA
Calithera Biosciences Inc.
$0.52+0.0678  +14.99%
PALI
Palisade Bio Inc.
$1.21+0.155  +14.69%
RMTI
Rockwell Medical Inc.
$0.45+0.0568  +14.45%
VRPX
Virpax Pharmaceuticals Inc.
$2.63+0.3301  +14.35%
NRBO
NeuroBo Pharmaceuticals Inc.
$1.28+0.16  +14.29%

Pre-Market Decliners

CompanyPriceChange
ARDS
Aridis Pharmaceuticals Inc.
$1.32-0.28  -17.50%
HILS
Hillstream BioPharma Inc.
$2.89-0.47  -13.99%
CINC
CinCor Pharma Inc.
$15.66-2.54  -13.96%
RUBY
Rubius Therapeutics Inc.
$6.54-0.7615  -10.43%
GMDA
Gamida Cell Ltd.
$2.95-0.29  -8.95%
KPTI
Karyopharm Therapeutics Inc.
$7.63-0.65  -7.85%
BDSI
BioDelivery Sciences International Inc.
$3.10-0.26  -7.74%
ITCI
Intra-Cellular Therapies Inc.
$39.57-3.09  -7.24%
BNTC
Benitec Biopharma Inc.
$2.31-0.18  -7.23%
VAXX
Vaxxinity Inc.
$7.57-0.59  -7.23%