BPC January 03 update

Applied APLR NDA delay; Genprex GNPX Fast Track Designation

Pre-Market Updates

Applied Therapeutics, Inc. (NASDAQ: APLT) announced that following discussions with the FDA, it decided to hold off on submitting a New Drug Application (NDA) for AT-007 for treatment of Galactosemia.

Genprex, Inc. (NASDAQ: GNPX) announced that the FDA granted Fast Track Designation (FTD) for REQORSA in combination with Merck & Co's (NYSE: MRK) Keytruda to treat non-small cell lung cancer (NSCLC).

Xeris Biopharma Holdings, Inc. (NASDAQ: XERS) announced that it entered into a private placement with an affiliate of Armistice Capital, LLC for aggregate gross proceeds of approximately $30 million.

NRx Pharmaceuticals (NASDAQ: NRXP) filed a provisional composition of matter patent application with the US Patent and Trademark Office for compositions of vasoactive intestinal peptide, a synthetic form of aviptadil, that is both shelf-stable and biologically active when used to treat COVID-19 and other diseases.

Ovid Therapeutics Inc. (NASDAQ: OVID) entered into an exclusive license agreement with AstraZeneca (NASDAQ: AZN) for a library of early-stage small molecules targeting the KCC2 transporter, including lead candidate OV350. AstraZeneca will receive $5 million in cash and $7.5 million in shares of Ovid stock upfront, as well as $53 million in milestone payments.

Pieris Pharmaceuticals, Inc. (NASDAQ: PIRS) announced the successful completion of the sponsor safety review of part 1a of its Phase 2a study of PRS-060/AZD1402 to treat moderate-to-severe asthma.

Pre-Market Advancers

CompanyPriceChange
CGTX
Cognition Therapeutics Inc.
$4.30+0.8  +22.86%
HOOK
HOOKIPA Pharma Inc.
$1.79+0.29  +19.33%
MRKR
Marker Therapeutics Inc.
$0.71+0.11  +18.33%
IMMX
Immix Biopharma Inc.
$5.31+0.8  +17.74%
BSGM
BioSig Technologies Inc.
$2.10+0.3  +16.67%
CALA
Calithera Biosciences Inc.
$0.52+0.0678  +14.99%
PALI
Palisade Bio Inc.
$1.21+0.155  +14.69%
RMTI
Rockwell Medical Inc.
$0.45+0.0568  +14.45%
VRPX
Virpax Pharmaceuticals Inc.
$2.63+0.3301  +14.35%
NRBO
NeuroBo Pharmaceuticals Inc.
$1.28+0.16  +14.29%

Pre-Market Decliners

CompanyPriceChange
ARDS
Aridis Pharmaceuticals Inc.
$1.32-0.28  -17.50%
HILS
Hillstream BioPharma Inc.
$2.89-0.47  -13.99%
CINC
CinCor Pharma Inc.
$15.66-2.54  -13.96%
RUBY
Rubius Therapeutics Inc.
$6.54-0.7615  -10.43%
GMDA
Gamida Cell Ltd.
$2.95-0.29  -8.95%
KPTI
Karyopharm Therapeutics Inc.
$7.63-0.65  -7.85%
BDSI
BioDelivery Sciences International Inc.
$3.10-0.26  -7.74%
ITCI
Intra-Cellular Therapies Inc.
$39.57-3.09  -7.24%
BNTC
Benitec Biopharma Inc.
$2.31-0.18  -7.23%
VAXX
Vaxxinity Inc.
$7.57-0.59  -7.23%