BPC November 23 update

Aadi AADI Approval; Aptevo APVO Phase 1b data

Pre-Market Updates

Aadi Bioscience, Inc. (NASDAQ: AADI) announced that the FDA approved FYARRO to treat metastatic malignant perivascular epithelioid cell tumor (PEComa) in adults.

Aptevo Therapeutics Inc. (NASDAQ: APVO) released data from its Phase 1b expansion trial of APVO436 to treat acute myeloid leukemia (AML). Preliminary data observed one complete remission.

Adamis Pharmaceuticals Corporation (NASDAQ: ADMP) reported third-quarter earnings yesterday with sales of $3.4 million.

Qualigen Therapeutics, Inc. (NASDAQ: QLGN) continues to rally in the pre-market following a Zach’s Small Cap report noting a $9 price target for the company.

Amryt Pharma Plc (NASDAQ: AMYT) announced that the FDA extended the PDUFA target action date by three months to February 28, 2022, for Oleogel-S10 to treat Junctional and Dystrophic Epidermolysis Bullosa (EB).

Synlogic, Inc. (NASDAQ: SYBX) presented interim data from its Phase 2 SynPheny-1 trial of SYNB1618 to treat phenylketonuria (PKU). Data reported a 40% reduction in D5-Phe absorption after a meal challenge, a 20% reduction in mean fasting plasma Phe across all subjects, and a >250 µM mean reduction in fasting plasma Phe.

Tonix Pharmaceuticals Holding Corp. (NASDAQ: TNXP) announced the FDA cleared its Investigational New Drug (IND) Application for a Phase 2 study of TNX-1900 (intranasal potentiated oxytocin) to treat migraines.

Pre-Market Advancers

CompanyPriceChange
PTN
Palatin Technologies Inc.
$0.79+0.2324  +41.68%
STSA
Satsuma Pharmaceuticals Inc.
$5.96+0.71  +13.52%
BYSI
BeyondSpring Inc.
$16.25+1.9  +13.24%
ACHL
Achilles Therapeutics plc
$5.39+0.55  +11.36%
OGEN
Oragenics Inc.
$0.60+0.0488  +8.87%
DRMA
Dermata Therapeutics Inc.
$2.93+0.23  +8.52%
UNCY
Unicycive Therapeutics Inc.
$3.16+0.24  +8.22%
WDNA
WisdomTree BioRevolution Fund
$26.00+1.8493  +7.66%
LOGC
LogicBio Therapeutics Inc.
$3.15+0.21  +7.14%
URGN
UroGen Pharma Ltd.
$13.00+0.86  +7.08%

Pre-Market Decliners

CompanyPriceChange
NAVB
Navidea Biopharmaceuticals Inc.
$1.15-0.15  -11.54%
IKT
Inhibikase Therapeutics Inc.
$1.91-0.15  -7.28%
PSTI
Pluristem Therapeutics Inc.
$2.52-0.17  -6.32%
BPTS
Biophytis SA
$5.40-0.36  -6.25%
APVO
Aptevo Therapeutics Inc.
$12.26-0.81  -6.20%
ANGN
Angion Biomedica Corp.
$3.54-0.2099  -5.60%
PBLA
Panbela Therapeutics Inc.
$1.86-0.11  -5.58%
VLON
Vallon Pharmaceuticals Inc.
$5.05-0.26  -4.90%
RVPH
Reviva Pharmaceuticals Holdings Inc.
$3.60-0.18  -4.76%
CRNX
Crinetics Pharmaceuticals Inc.
$23.25-1.15  -4.71%