MIRM Mirum Pharmaceuticals Inc.

18.72
-0.37  -2%
Previous Close 19.09
Open 18.91
52 Week Low 9.14
52 Week High 27.43
Market Cap $551,619,937
Shares 29,466,877
Float 15,930,929
Enterprise Value $423,042,950
Volume 88,721
Av. Daily Volume 238,838
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Drug Pipeline

Drug Stage Notes
Maralixibat
Alagille Syndrome (ALGS)
NDA Filing
NDA Filing
Rolling NDA has been completed - February 1, 2021.
Volixibat (VISTAS)
Primary sclerosing cholangitis
Phase 2b
Phase 2b
Phase 2b commencement of enrollment announced January 14, 2021.
Volixibat
Pruritus associated with primary biliary cholangitis
Phase 2b
Phase 2b
Phase 2b trial to be initiated 2H 2021.
Volixiba
Intrahepatic cholestasis of pregnancy
Phase 2
Phase 2
Phase 2a/2b trial planned for 1Q 2021.
Maralixibat
Biliary atresia
Phase 2
Phase 2
Phase 2 study initiation due 1Q 2021.
Maralixibat - MARCH
Progressive Familial Intrahepatic Cholestasis (PFIC)
Phase 3
Phase 3
Phase 3 enrollment to be completed 2Q 2021.

Latest News

  1. Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that the company will participate in the following upcoming virtual investor conferences:

    SVB Leerink 10th Annual Global Healthcare Conference
    Friday, February 26, 2021 at 3:40 p.m. ET

    Raymond James Virtual Institutional Investors Conference
    Wednesday, March 3, 2021 at 3:00 p.m. ET

    H.C. Wainwright Global Life Sciences Conference
    The presentation will be available for viewing on Tuesday, March 9, 2021 at 7:00 a.m. ET.

    Oppenheimer 31st Annual Healthcare Conference
    Wednesday, March 17, 2021 at 4:30 p.m. ET

    The audio webcasts, on-demand presentation, and an archive of all presentations will be available in the Investors & Media section of Mirum's website at ir.mirumpharma.com.

    About

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that the company will participate in the following upcoming virtual investor conferences:

    SVB Leerink 10th Annual Global Healthcare Conference

    Friday, February 26, 2021 at 3:40 p.m. ET

    Raymond James Virtual Institutional Investors Conference

    Wednesday, March 3, 2021 at 3:00 p.m. ET

    H.C. Wainwright Global Life Sciences Conference

    The presentation will be available for viewing on Tuesday, March 9, 2021 at 7:00 a.m. ET.

    Oppenheimer 31st Annual Healthcare Conference

    Wednesday, March 17, 2021 at 4:30 p.m. ET

    The audio webcasts, on-demand presentation, and an archive of all presentations will be available in the Investors & Media section of Mirum's website at ir.mirumpharma.com.

    About Mirum Pharmaceuticals

    Mirum Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a late-stage pipeline of novel therapies for debilitating liver diseases. Mirum's lead product candidate, maralixibat, is an investigational oral drug in development for Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Mirum has submitted an NDA for maralixibat in the treatment of cholestatic pruritus in patients with ALGS. Additionally, Mirum's marketing authorization application for the treatment of pediatric patients with PFIC2 has been accepted for review (validated) by the European Medicines Agency.

    Mirum is also developing volixibat, also an oral ASBT-inhibitor, in primary sclerosing cholangitis, intrahepatic cholestasis of pregnancy, and primary biliary cholangitis. For more information, visit MirumPharma.com.

    Follow Mirum on Twitter, Facebook, LinkedIn and Instagram.

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  2. - Maralixibat U.S. launch expected in second half of 2021, if approved

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced it has completed submission of its rolling New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for maralixibat for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) one year of age and older. ALGS is a rare liver disease for which there are currently no approved therapies. The company is planning for the U.S. launch of maralixibat in the second half of 2021, should the medication be approved by the FDA for this indication.

    The NDA submission included the results of the ICONIC study and additional supportive studies totaling 86 patients with ALGS with up to six-year…

    - Maralixibat U.S. launch expected in second half of 2021, if approved

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced it has completed submission of its rolling New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for maralixibat for the treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) one year of age and older. ALGS is a rare liver disease for which there are currently no approved therapies. The company is planning for the U.S. launch of maralixibat in the second half of 2021, should the medication be approved by the FDA for this indication.

    The NDA submission included the results of the ICONIC study and additional supportive studies totaling 86 patients with ALGS with up to six-year follow-up. The clinical safety data submitted for maralixibat includes over 1,600 individuals treated.

    "Patients, families and physicians have an urgent need for effective medications to address the severe and life-altering symptoms associated with ALGS," said Chris Peetz, president and chief executive officer at Mirum. "This submission brings us one step closer to a potential approval of maralixibat and providing a much-needed treatment option for the patients and their families suffering with ALGS."

    Until maralixibat is approved by the FDA for prescription, maralixibat is available to eligible patients with ALGS through Mirum's Expanded Access Program (EAP). The EAP is available in the United States, Canada, Australia and in regions throughout Europe. Requests for expanded access to maralixibat must be made by a licensed physician. Physicians and patients can learn more about the maralixibat EAP by visiting the program website at www.ALGSEAP.com or via Clinicaltrials.gov. Physicians in the United States and Canada who would like to request access for their patients can email . Physicians in Europe and Australia can contact with a reference line of "Mirum ALGS EAP request".

    Maralixibat was granted Rare Pediatric Disease Designation for ALGS and, as such, may qualify for receipt of a priority review voucher, if approved by the FDA. Maralixibat was also granted Breakthrough Therapy Designation for the treatment of pruritus associated with ALGS in patients one year of age and older. Maralixibat was granted Orphan Drug Designation by the FDA for the treatment of patients with PFIC and ALGS.

    About Alagille syndrome

    Alagille syndrome (ALGS) is a rare genetic disorder in which bile ducts are abnormally narrow, malformed and reduced in number, which leads to bile accumulation in the liver and ultimately progressive liver disease. The estimated incidence of ALGS is one in every 30,000 people.1 In patients with ALGS, multiple organ systems may be affected by the mutation, including the liver, heart, kidneys and central nervous system.2 The accumulation of bile acids prevents the liver from working properly to eliminate waste from the bloodstream and, according to recent reports, 60% to 75% of patients with ALGS have a liver transplant before reaching adulthood.3 Signs and symptoms arising from liver damage in ALGS may include jaundice (yellowing of the skin), xanthomas (disfiguring cholesterol deposits under the skin), and pruritus (itch)2. The pruritus experienced by patients with ALGS is among the most severe in any chronic liver disease and is present in most affected children by the third year of life.4

    About Maralixibat

    Maralixibat is a novel, minimally absorbed, orally administered investigational drug being evaluated in several rare cholestatic liver diseases. Maralixibat inhibits the apical sodium dependent bile acid transporter (ASBT), resulting in more bile acids being excreted in the feces, leading to lower levels of bile acids systemically, thereby potentially reducing bile acid mediated liver damage and related effects and complications. More than 1,600 individuals have received maralixibat, including more than 120 children who have received maralixibat as an investigational treatment for Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC). In the ICONIC Phase 2b ALGS clinical trial, patients taking maralixibat had significant reductions in bile acids and pruritus compared to placebo, as well as reduction in xanthomas and accelerated growth long-term. In a Phase 2 PFIC study, a genetically defined subset of BSEP deficient (PFIC2), patients responded to maralixibat with an increase in transplant-free survival. The U.S. Food and Drug Administration has granted maralixibat Breakthrough Therapy designation for the treatment of pruritus associated with ALGS in patients one year of age and older and for PFIC2. Maralixibat was generally well-tolerated throughout the studies. The most frequent treatment-related adverse events were diarrhea and abdominal pain. Until maralixibat is approved and available for prescribing, the medication is available to patients with ALGS through Mirum's expanded access program. For more information, please visit ALGSEAP.com. For more information about the Phase 3 study for maralixibat in pediatric patients with PFIC, visit PFICtrial.com.

    About Mirum

    Mirum Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a late-stage pipeline of novel therapies for debilitating liver diseases. Mirum's lead product candidate, maralixibat, is an investigational oral drug in development for Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Mirum has submitted an NDA for maralixibat in the treatment of cholestatic pruritus in patients with ALGS. Additionally, Mirum's marketing authorization application for the treatment of pediatric patients with PFIC2 has been accepted for review (validated) by the European Medicines Agency.

    Mirum is also developing volixibat, also an oral ASBT-inhibitor, in primary sclerosing cholangitis, intrahepatic cholestasis of pregnancy, and primary biliary cholangitis. For more information, visit MirumPharma.com.

    Follow Mirum on Twitter, Facebook, LinkedIn and Instagram.

    Forward Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements regarding, among other things, the regulatory approval path for maralixibat in the United States. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as "plans," "will," "may," "anticipates," "expects," "potential" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Mirum's current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks and uncertainties associated with Mirum's business in general, the impact of the COVID-19 pandemic, and the other risks described in Mirum's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Mirum undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

    References

    1Danks, et al. Archives of Disease in Childhood 1977

    2Johns Hopkins Medicine. hopkinsmedicine.org/health/conditions-and-diseases/Alagille-syndrome

    3Vandriel, et al. GALA EASL 2020; Kamath, et al. Hepatology Communications 2020

    4Elisofon, et al. Journal of Pediatric Gastroenterology and Nutrition 2010

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  3. - The national campaign seeks to emphasize the unbearable burden ALGS has on patients and their families.

    - Mirum underscores its commitment to continued understanding of the rare liver disease through research and support of ALGS community.

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced the launch of a disease awareness campaign for Alagille syndrome (ALGS), a rare cholestatic liver disease affecting one in every 30,000 births worldwide. The campaign seeks to broaden awareness and education of ALGS so that healthcare providers can more readily identify symptoms and diagnose patients with the goal to improve time to diagnosis and treatment.

    Children with ALGS live with severe and unrelenting symptoms that can impact their overall…

    - The national campaign seeks to emphasize the unbearable burden ALGS has on patients and their families.

    - Mirum underscores its commitment to continued understanding of the rare liver disease through research and support of ALGS community.

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced the launch of a disease awareness campaign for Alagille syndrome (ALGS), a rare cholestatic liver disease affecting one in every 30,000 births worldwide. The campaign seeks to broaden awareness and education of ALGS so that healthcare providers can more readily identify symptoms and diagnose patients with the goal to improve time to diagnosis and treatment.

    Children with ALGS live with severe and unrelenting symptoms that can impact their overall quality of life. Identifying these symptoms early on can lead to a diagnosis and an effective treatment plan.

    "Many patients live for months or years before being diagnosed and some patients are misdiagnosed, leading to unnecessary and invasive surgeries that do not address the underlying cause of their liver disease," said Chris Peetz, president and chief executive officer at Mirum. "Our objective is to provide a platform that helps healthcare providers understand the specific signs and symptoms of ALGS so they can be better equipped to identify and diagnose this rare disease and help their patients get the treatment they need."

    "This disease awareness campaign has the potential to help healthcare providers recognize Alagille syndrome in their patients in order to properly address this rare disease," said Roberta Smith, president of the Alagille syndrome Alliance and parent of a child with ALGS. "The impacts of Alagille syndrome on families are many. We have only begun to scratch the surface in understanding disease burden and specifically, how different regions in the world are affected differently. As we celebrate International Alagille Syndrome Awareness Day, we will focus on sharing Alagille syndrome family stories that emphasize the critical need for continued research and treatment options for patients worldwide. The patient voice is the Alagille syndrome community's greatest vehicle for change."

    Mirum's goal is to advance the understanding and diagnosis of ALGS so that patients and their families will get the medical care and support they need to improve their quality of life. The company and its founders have been dedicated to understanding ALGS through the support of resources like the Global Alagille Alliance (GALA) for continued research, as well as genetic testing platforms that help effectively identify ALGS in patients. These resources assist in advancing research and the healthcare community's understanding of this devastating rare disease.

    Visit the Unbearable ALGS website to learn more about Alagille syndrome and the significant impact it has on patients and their families.

    Alagille syndrome Awareness Day – January 24, 2021

    Mirum is also proud to champion the Alagille syndrome Alliance and their ongoing work to support ALGS families through education, outreach, and community. This year, in celebration of International ALGS Awareness Day, they are hosting a 24-hour Aware-a-Thon that will include family stories, messages, expert talks, and educational resources aimed at increasing the public's awareness of ALGS, a crucial element in their mission. To learn more about how to get involved and support the ALGS Alliance and the ALGS community, visit their Awareness Day website.

    About Alagille syndrome

    Alagille syndrome (ALGS) is a rare genetic disorder in which bile ducts are abnormally narrow, malformed and reduced in number, which leads to bile accumulation in the liver and ultimately progressive liver disease. The estimated incidence of ALGS is one in every 30,000 people.1 In patients with ALGS, multiple organ systems may be affected by the mutation, including the liver, heart, kidneys and central nervous system.2 The accumulation of bile acids prevents the liver from working properly to eliminate waste from the bloodstream and, according to recent reports, 60% to 75% of patients with ALGS have a liver transplant before reaching adulthood.3 Signs and symptoms arising from liver damage in ALGS may include jaundice (yellowing of the skin), xanthomas (disfiguring cholesterol deposits under the skin), and pruritus (itch)2. The pruritus experienced by patients with ALGS is among the most severe in any chronic liver disease and is present in most affected children by the third year of life.4

    About Mirum

    Mirum Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a late-stage pipeline of novel therapies for debilitating liver diseases. Mirum's lead product candidate, maralixibat, is an investigational oral drug in development for Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Mirum has initiated a rolling NDA submission for maralixibat in the treatment of cholestatic pruritus in patients with ALGS and expects to complete the submission in the first quarter of 2021. Additionally, Mirum's marketing authorization application for the treatment of pediatric patients with PFIC2 has been accepted for review (validated) by the European Medicines Agency.

    Mirum is also developing volixibat, also an oral ASBT-inhibitor, in primary sclerosing cholangitis, intrahepatic cholestasis of pregnancy, and primary biliary cholangitis. For more information, visit MirumPharma.com.

    Follow Mirum on Twitter, Facebook, LinkedIn and Instagram.

    Forward Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements regarding, among other things, the regulatory approval path for maralixibat in the United States and the European Union, and Mirum's ALGS disease awareness campaign. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as "plans," "goal", "will," "may," "expects," "potential" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Mirum's current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks and uncertainties associated with Mirum's business in general, the impact of the COVID-19 pandemic, and the other risks described in Mirum's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Mirum undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

    References

    1Danks, et al. Archives of Disease in Childhood 1977

    2Johns Hopkins Medicine. hopkinsmedicine.org/health/conditions-and-diseases/Alagille-syndrome

    3Vandriel, et al. GALA EASL 2020; Kamath, et al. Hepatology Communications 2020

    4Elisofon, et al. Journal of Pediatric Gastroenterology and Nutrition 2010

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  4. Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that the first patient has been enrolled in Mirum's Phase 2b VISTAS study evaluating volixibat in adult patients with primary sclerosing cholangitis (PSC), an idiopathic chronic cholestatic liver disease characterized by progressive inflammation and destruction of bile ducts often leading to serious liver disease, cancer, and ultimately liver failure. Volixibat, an oral, minimally absorbed medication, is designed to offer a novel approach in the treatment of adult cholestatic diseases by blocking the recycling of bile acids through inhibition of the apical sodium dependent bile acid transporter (ASBT), thereby reducing bile acids systemically and in the liver.

    Patients meeting eligibility…

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that the first patient has been enrolled in Mirum's Phase 2b VISTAS study evaluating volixibat in adult patients with primary sclerosing cholangitis (PSC), an idiopathic chronic cholestatic liver disease characterized by progressive inflammation and destruction of bile ducts often leading to serious liver disease, cancer, and ultimately liver failure. Volixibat, an oral, minimally absorbed medication, is designed to offer a novel approach in the treatment of adult cholestatic diseases by blocking the recycling of bile acids through inhibition of the apical sodium dependent bile acid transporter (ASBT), thereby reducing bile acids systemically and in the liver.

    Patients meeting eligibility criteria for the study are randomized to receive volixibat 20 mg twice daily (BID) or 80 mg BID, or placebo for 28 weeks, after which time all patients will receive volixibat through the open-label extension phase of the study.

    The primary endpoint will evaluate the change in pruritus from baseline for volixibat versus placebo using the Adult ItchRO tool. Secondary endpoints evaluated will include safety and tolerability, quality of life measures, and serum bile acids. Exploratory endpoints will include assessments of liver fibrosis and other markers of PSC progression.

    "This study is an important step forward in evaluating the potential clinical benefit of volixibat in adult patients with primary sclerosing cholangitis," said Christopher Bowlus, MD, chief of gastroenterology and hepatology at UC Davis Health. "There are currently no approved therapies indicated for the treatment of patients with PSC suffering from pruritus, a common and often debilitating symptom of the disease."

    "We are excited to initiate the volixibat Phase 2 VISTAS study for patients with primary sclerosing cholangitis," said Ed Tucker, MD, chief medical officer at Mirum. "Our learnings from the maralixibat development program have informed the design of our volixibat study with the hope of alleviating the burdensome effects experienced by patients with PSC."

    Mirum has ongoing studies evaluating cholestatic liver diseases in pediatric patients with maralixibat, also an ASBT inhibitor. The company has initiated a rolling NDA submission to the U.S. Food and Drug Administration (FDA) for maralixibat for the treatment of cholestatic pruritus associated with Alagille syndrome, which Mirum expects to complete this quarter. Mirum is planning for a U.S. launch in the second half of 2021, should Mirum receive FDA approval for this indication. Until that time, maralixibat is available to eligible patients in the United States, Canada, Australia and in regions throughout Europe through an Expanded Access Program. Additionally, Mirum submitted a marketing authorization application which was accepted (validated) by the European Medicines Agency for maralixibat for the treatment of patients with progressive familial intrahepatic cholestasis (PFIC), type 2.

    About Primary Sclerosing Cholangitis

    Primary sclerosing cholangitis (PSC) is a rare, serious, idiopathic chronic cholestatic liver disease characterized by cholestasis, progressive inflammation, and destruction of bile ducts, which may lead to fibrosis, cirrhosis, portal hypertension, cancer, and ultimately liver failure. It is estimated that approximately 29,000 people in the United States and approximately 50,000 people in Europe suffer from PSC with no approved therapies. The underlying etiology of PSC is not completely understood, but it is thought to arise from a combination of genetic and environmental factors. The median age at diagnosis is approximately 35 years, and approximately 70% of PSC patients have inflammatory bowel disease, principally ulcerative colitis. Signs and symptoms of PSC may include, but are not limited to, pruritus, extreme fatigue, jaundice, and abdominal discomfort. The eventual buildup of bile acids from continued bile duct injury and obstruction damages liver cells and is thought to contribute to the progression of liver failure. Complications involving the biliary tree are common and include cholangitis, as well as ductal strictures and gallstones, the latter of which frequently require endoscopic or surgical interventions. PSC also increases the risk of development of malignancies, with cholangiocarcinoma being the most common. PSC is the fifth leading indication for liver transplantation; however, the post-transplant recurrence rate of PSC is up to 25%.

    About Volixibat

    Volixibat is an oral, minimally absorbed agent designed to selectively inhibit the apical sodium dependent bile acid transporter (ASBT). Volixibat may offer a novel approach in the treatment of adult cholestatic diseases by blocking the recycling of bile acids, through inhibition of ASBT, thereby reducing bile acids systemically and in the liver. Phase 1 and Phase 2 studies of volixibat demonstrated on-target fecal bile acid excretion, a pharmacodynamic marker of ASBT inhibition, in addition to decreases in LDL cholesterol and increases in 7αC4 which are markers of bile acid synthesis. Volixibat has been evaluated in more than 400 individuals across multiple clinical trials. The most common adverse events reported were mild to moderate gastrointestinal events observed in the volixibat groups.

    About Mirum

    Mirum Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a late-stage pipeline of novel therapies for debilitating liver diseases. Mirum's lead product candidate, maralixibat, is an investigational oral drug in development for Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Mirum has initiated a rolling NDA submission for maralixibat for the treatment of cholestatic pruritus in patients with ALGS and expects to complete the submission in the first quarter of 2021. Additionally, Mirum's marketing authorization application for the treatment of pediatric patients with PFIC2 has been accepted for review (validated) by the European Medicines Agency.

    Mirum is also developing volixibat, also an oral ASBT inhibitor, to evaluate its potential in treating primary sclerosing cholangitis, intrahepatic cholestasis of pregnancy, and primary biliary cholangitis. For more information, visit MirumPharma.com.

    Follow Mirum on Twitter, Facebook, LinkedIn and Instagram.

    Forward Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements include statements regarding, among other things, the conduct and progress of Mirum's ongoing and planned studies for volixibat, and the regulatory approval path for maralixibat and volixibat. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as "plans," "will," "may," "expects," "potential" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Mirum's current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks and uncertainties associated with Mirum's business in general, the impact of the COVID-19 pandemic, and the other risks described in Mirum's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made and are based on management's assumptions and estimates as of such date. Mirum undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

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  5. Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that it will present at the annual J.P. Morgan Healthcare Conference taking place virtually January 11-14, 2021.

    Chris Peetz, Mirum's president and chief executive officer, will provide an overview of Mirum's strategy, as well as the company's commercialization plans for maralixibat and its ongoing development of both maralixibat and volixibat. Mr. Peetz and members of Mirum's leadership team will be available for one-on-one meetings during the conference.

    Presentation and Q&A Session

    Date: Tuesday, January 12, 2021
    Time: 5:20 – 6:00 p.m. ET

    A live audio webcast and archive of Mirum's presentation along with accompanying slides will be available in the Investors & Media section of…

    Mirum Pharmaceuticals, Inc. (NASDAQ:MIRM) today announced that it will present at the annual J.P. Morgan Healthcare Conference taking place virtually January 11-14, 2021.

    Chris Peetz, Mirum's president and chief executive officer, will provide an overview of Mirum's strategy, as well as the company's commercialization plans for maralixibat and its ongoing development of both maralixibat and volixibat. Mr. Peetz and members of Mirum's leadership team will be available for one-on-one meetings during the conference.

    Presentation and Q&A Session

    Date: Tuesday, January 12, 2021

    Time: 5:20 – 6:00 p.m. ET

    A live audio webcast and archive of Mirum's presentation along with accompanying slides will be available in the Investors & Media section of the company's website at ir.mirumpharma.com.

    Additionally, the company will present during a fireside chat at the upcoming H.C. Wainwright Virtual BIOCONNECT 2021 Conference. A webcast of the presentation will be accessible from the Investors & Media section of Mirum's website at ir.mirumpharma.com beginning January 11, 2021.

    About Mirum

    Mirum Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on the development and commercialization of a late-stage pipeline of novel therapies for debilitating liver diseases. Mirum's lead product candidate, maralixibat, is an investigational oral drug in development for Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Mirum has initiated a rolling NDA submission for maralixibat in the treatment of cholestatic pruritus in patients with ALGS and expects to complete the submission in the first quarter of 2021. Additionally, Mirum's marketing authorization application for the treatment of pediatric patients with PFIC2 has been accepted for review (validated) by the European Medicines Agency.

    Mirum is also developing volixibat, also an oral ASBT-inhibitor, in primary sclerosing cholangitis and intrahepatic cholestasis of pregnancy. For more information, visit MirumPharma.com.

    Follow Mirum on Twitter, Facebook, LinkedIn and Instagram.

    View Full Article Hide Full Article
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