1. SAN FRANCISCO and SAN DIEGO, Sept. 13, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced results from preclinical studies evaluating its lead Fibroblast Growth Factor Receptor (FGFR) inhibitor candidate, KIN-3248. These findings were presented during a virtual poster session at the joint JCA-AACR Precision Cancer Medicine International Conference that took place September 10-12, 2021.

    KIN-3248 is a next-generation, irreversible, small molecule pan-FGFR inhibitor designed to target cancer-associated FGFR2 and FGFR3 gene alterations, which are common…

    SAN FRANCISCO and SAN DIEGO, Sept. 13, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced results from preclinical studies evaluating its lead Fibroblast Growth Factor Receptor (FGFR) inhibitor candidate, KIN-3248. These findings were presented during a virtual poster session at the joint JCA-AACR Precision Cancer Medicine International Conference that took place September 10-12, 2021.

    KIN-3248 is a next-generation, irreversible, small molecule pan-FGFR inhibitor designed to target cancer-associated FGFR2 and FGFR3 gene alterations, which are common oncogenic drivers seen in human cancers. KIN-3248 was developed to address both primary FGFR2 and FGFR3 oncogenic alterations and those predicted to drive acquired resistance to current FGFR-targeted therapies, including gatekeeper, molecular brake, and activation loop mutations observed in cancers such as intrahepatic cholangiocarcinoma (ICC) and urothelial carcinoma (UC). Kinnate anticipates filling an Investigational New Drug (IND) application for KIN-3248 with the U.S. Food and Drug Administration (FDA) in the first half of 2022.

    "We are very pleased with the progress of our FGFR program, and these positive preclinical data are an important indicator of the potential anti-tumor activity of KIN-3248," said Eric Martin, Ph.D., SVP, Translational Research and Medicine at Kinnate. "In preclinical studies, we have demonstrated inhibitory activity across a wide range of clinically relevant mutations that drive primary disease and acquired resistance. We believe that by addressing these mutations and broadly covering multiple FGFR isoforms, KIN-3248 may be able to overcome challenges associated with currently approved FGFR inhibitors and provide a meaningful increase in the duration of response."

    The poster presentation, delivered by Aleksandra Franovic, Ph.D., Senior Director of Translational Medicine at Kinnate, highlights data which show that in biochemical and cellular assays, KIN-3248 exhibited nanomolar potency against all four wild-type FGFR family members but not against other non-FGFR kinases. Importantly, KIN-3248 was active against mutations associated with resistance to FGFR inhibitors both in the clinic and in experimental models, including the FGFR2 and FGFR3 gatekeeper (V565X and V555M, respectively), molecular brake (N550X and N540X, respectively), and activation loop (L618V and K650M, respectively) mutations with less than a five-fold difference in IC50 values relative to corresponding wild-type receptors. In addition, dose-dependent inhibition of FGFR2- and FGFR3-driven human in vivo xenografts, including one with an acquired gatekeeper mutation, was attained with once-daily KIN-3248 treatment and was well tolerated. This efficacy was accompanied by both pharmacodynamic biomarker modulation and downstream pathway inhibition.

    Kinnate's poster presentation, titled "The next-generation FGFR inhibitor, KIN-3248, is active against acquired FGFR2 and FGFR3 gatekeeper and molecular brake drug resistance mutations," is available for on-demand viewing and can be accessed via: https://www.c-linkage.co.jp/jca-aacr2021.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the expected timing for our regulatory filings and the potential benefits of our product candidates. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



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  2. Announced first patient dosed in Phase 1 trial evaluating KIN-2787 in patients with BRAF mutation-positive solid tumors

    Strengthened management team and Board of Directors with key appointments

    Ended the quarter with cash, cash equivalents and investments of $365.1 million, exclusive of $35.0 million in its China joint venture

    SAN FRANCISCO and SAN DIEGO, Aug. 16, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced financial results for the quarter ended June 30, 2021. The company also announced that the first patient has commenced treatment in…

    Announced first patient dosed in Phase 1 trial evaluating KIN-2787 in patients with BRAF mutation-positive solid tumors

    Strengthened management team and Board of Directors with key appointments

    Ended the quarter with cash, cash equivalents and investments of $365.1 million, exclusive of $35.0 million in its China joint venture

    SAN FRANCISCO and SAN DIEGO, Aug. 16, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced financial results for the quarter ended June 30, 2021. The company also announced that the first patient has commenced treatment in its Phase 1 KN-8701 clinical trial evaluating its lead RAF product candidate, KIN-2787, a pan-RAF inhibitor being developed for the treatment of patients with lung cancer, melanoma and other solid tumors.

    "2021 continues to be a year of progress for Kinnate. Initiating our first in-human trial for KIN-2787 and dosing our first patient were important steps forward toward expanding options for cancer patients who are not benefiting from currently approved RAF inhibitors," said Nima Farzan, Chief Executive Officer of Kinnate. "As we enter the second half of the year, our expanding team of clinical and business leaders are well positioned to drive further progress in our KIN-2787 program and advance our pipeline of targeted precision oncology therapies, including our lead FGFR inhibitor candidate for which we anticipate filing an IND in the first half of 2022."

    The KN-8701 trial is a multi-center, open-label, two-part study of approximately 115 patients to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with Class I, Class II, or Class III BRAF-mutated advanced or metastatic solid tumors.

    "Successfully targeting patients with Class II and Class III BRAF mutations remains a substantial unmet need in cancer care. KIN-2787 brings a unique approach to potentially address the shortcomings of existing therapies by inhibiting dimer signaling in specific patient populations with BRAF mutations while also minimizing MAPK paradoxical activation," said Meredith McKean, MD, MPH, Associate Director, Melanoma and Skin Cancer Research Program, Sarah Cannon Research Institute at Tennessee Oncology. "We are proud to be the first site to treat a patient with KIN-2787 and look forward to working with Kinnate to continue enrollment in this important Phase 1 trial."

    Other Recent Business Highlights and Corporate Update:

    • In May 2021, we closed a $35 million Series A preferred stock financing of a China joint venture ("China JV"), of which Kinnate is the majority shareholder. Established with OrbiMed Asia Partners, OrbiMed Private Investments and Foresite Capital, the China JV will be headquartered in Shanghai and the financing will enable the potential development and commercialization by the China JV of certain Kinnate targeted oncology product candidates across Greater China (PRC, Hong Kong, Taiwan, and Macau).
    • We appointed Neha Krishnamohan as our Chief Financial Officer and Executive Vice President, Corporate Development, and we continued to expand our leadership team, including with the appointment of Ken Kobayashi, M.D., our Senior Vice President, Clinical Development.
    • Helen Sabzevari, Ph.D. was appointed to our Board of Directors, and Stephen Kaldor, Ph.D., one of our founders, was not nominated for re-election to our Board of Directors when his term expired at our 2021 annual meeting of shareholders.
    • We expanded our organization to 52 full-time employees at June 30, 2021, of which 39 were engaged in research and development activities.
    • During a virtual poster session at the 57th Annual Meeting of the American Society of Clinical Oncology (ASCO), we presented results from preclinical studies evaluating the efficacy and tolerability of KIN-2787, in vitro and in vivo in BRAF mutation-driven human cancer models.

    Second Quarter 2021 Financial Results

    • Second quarter net loss for 2021 was $21.4 million, compared to $7.6 million for the same period in 2020.
    • Second quarter research and development expenses for 2021 were $16.2 million, compared to $5.6 million for the same period in 2020.
    • Second quarter general and administrative expenses for 2021 were $5.3 million, compared to $2.0 million for the same period in 2020.
    • As of June 30, 2021, the total of cash and cash equivalents and investments was $365.1 million, exclusive of $35.0 million in the China JV.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the development of our pipeline and the potential benefits of our drug discovery activities, the expected timing for our regulatory filings and enrollment and conduct of our clinical trials, the potential benefits and treatment indications of our product candidates and the expected expansion of our organization. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2021 that we are concurrently filing with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



     
    Kinnate Biopharma Inc.
    Condensed Consolidated Balance Sheets
    (Unaudited)
    (in thousands, except share and par value amounts)
         
      June 30, 2021 December 31, 2020
    Assets    
    Current assets:    
    Cash and cash equivalents $132,991  $365,462 
    Cash at consolidated joint venture  35,011   - 
    Short-term investments  87,017   31,398 
    Prepaid expenses and other current assets  3,761   3,343 
    Total current assets  258,780   400,203 
    Property and equipment, net  286   368 
    Long-term investments  145,136   - 
    Restricted cash  371   - 
    Other non-current assets  90   - 
    Total assets $404,663  $400,571 
         
    Liabilities and Stockholders' Equity     
    Current liabilities:    
    Accounts payable $1,334  $3,940 
    Accrued expenses  6,989   3,364 
    Total current liabilities  8,323   7,304 
    Commitments and contingencies    
    Redeemable noncontrolling interests  35,000   - 
    Stockholders' equity:    
    Preferred stock, $0.0001 par value; 200,000,000 shares authorized    
    at June 30, 2021 and December 31, 2020; 0 shares outstanding    
    at June 30, 2021 and December 31, 2020  -   - 
    Common stock, $0.0001 par value; 1,000,000,000 shares authorized    
    at June 30, 2021 and December 31, 2020; 43,622,745 and 43,477,439    
    shares issued and outstanding at June 30, 2021 and December 31, 2020,    
    respectively  4   4 
    Additional paid-in capital  453,641   446,601 
    Accumulated other comprehensive loss  (74)  (9)
    Accumulated deficit  (92,231)  (53,329)
    Total stockholders' equity  361,340   393,267 
    Total liabilities and equity $404,663  $400,571 
         





    Kinnate Biopharma Inc.
    Condensed Consolidated Statements of Operations and Comprehensive Loss
    (Unaudited)
    (in thousands, except share and per share amounts)
             
      Three Months Ended June 30, Six Months Ended June 30,
       2021   2020   2021   2020 
             
    Operating expenses:        
    Research and development $16,242  $5,579  $28,908  $8,777 
    General and administrative (includes related party amount of $92 for the three and six months ended June 30, 2020)  5,327   2,047   10,142   3,002 
    Total operating expenses  21,569   7,626   39,050   11,779 
    Loss from operations  (21,569)  (7,626)  (39,050)  (11,779)
    Other income:        
    Interest income  672   12   1,075   224 
    Other expense, net  (548)  -   (927)  - 
    Total other income, net  124   12   148   224 
    Net loss  (21,445)  (7,614)  (38,902)  (11,555)
    Net loss attributable to redeemable noncontrolling interests  -   -   -   - 
    Net loss attributable to Kinnate $(21,445) $(7,614) $(38,902) $(11,555)
             
    Weighted-average shares outstanding, basic and diluted  43,535,887   3,705,857   43,506,825   3,689,152 
    Net loss per share, basic and diluted $(0.49) $(2.05) $(0.89) $(3.13)
             
             
    Comprehensive loss:        
    Net loss $(21,445) $(7,614) $(38,902) $(11,555)
    Other comprehensive (loss) income:        
    Unrealized loss on investments  (34)  -   (65)  - 
    Total comprehensive loss  (21,479)  (7,614)  (38,967)  (11,555)
    Comprehensive loss attributable to noncontrolling interests  -   -   -   - 
    Comprehensive loss attributable to Kinnate $(21,479) $(7,614) $(38,967) $(11,555)

     

     



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  3. SAN FRANCISCO and SAN DIEGO, July 27, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that its Chief Executive Officer Nima Farzan will participate in the 2021 Wedbush PacGrow Healthcare Conference, being held virtually from August 10-11, 2021.

    Event: 2021 Wedbush PacGrow Healthcare Conference
    Panel: "Bullseye - Targeted Oncology Part 1"
    Location: Virtual
    Date: Tuesday, August 10, 2021
    Time: 10:55 AM ET/ 7:55 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the Wedbush panel…

    SAN FRANCISCO and SAN DIEGO, July 27, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that its Chief Executive Officer Nima Farzan will participate in the 2021 Wedbush PacGrow Healthcare Conference, being held virtually from August 10-11, 2021.

    Event: 2021 Wedbush PacGrow Healthcare Conference

    Panel: "Bullseye - Targeted Oncology Part 1"

    Location: Virtual

    Date: Tuesday, August 10, 2021

    Time: 10:55 AM ET/ 7:55 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the Wedbush panel discussion will be available in the Investors and Media section of the Kinnate website at www.kinnate.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, Kinnate's expected participation at investor conferences and meetings. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com 



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  4. SAN FRANCISCO and SAN DIEGO, July 07, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that its Chief Executive Officer Nima Farzan will participate in the William Blair Biotech Focus Conference 2021, being held virtually from July 14-15, 2021.

    Event: William Blair Biotech Focus Conference 2021
    Panel: "Next Generation Small Molecules in Oncology"
    Location: Virtual
    Date: Thursday, July 15, 2021
    Time: 9:00 AM ET/ 6:00 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the William…

    SAN FRANCISCO and SAN DIEGO, July 07, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that its Chief Executive Officer Nima Farzan will participate in the William Blair Biotech Focus Conference 2021, being held virtually from July 14-15, 2021.

    Event: William Blair Biotech Focus Conference 2021

    Panel: "Next Generation Small Molecules in Oncology"

    Location: Virtual

    Date: Thursday, July 15, 2021

    Time: 9:00 AM ET/ 6:00 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the William Blair panel discussion will be available in the Investors and Media section of the Kinnate website at www.kinnate.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, Kinnate's expected investor conference participation. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  5. SAN FRANCISCO and SAN DIEGO, June 28, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the appointment of Helen Sabzevari, Ph.D. to its Board of Directors. Dr. Sabzevari is a global thought leader who is internationally recognized for her work in the field of oncology. Her career-long efforts have helped bridge the gap between cancer cell biology and immunology, bringing these disciplines together to understand how the immune system and cancer cells interact on the broader system level and form the basis for many current efforts in immuno-oncology…

    SAN FRANCISCO and SAN DIEGO, June 28, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the appointment of Helen Sabzevari, Ph.D. to its Board of Directors. Dr. Sabzevari is a global thought leader who is internationally recognized for her work in the field of oncology. Her career-long efforts have helped bridge the gap between cancer cell biology and immunology, bringing these disciplines together to understand how the immune system and cancer cells interact on the broader system level and form the basis for many current efforts in immuno-oncology, particularly in the field of cancer vaccines.

    "We are honored to welcome Helen to the Kinnate Board of Directors. She is internationally recognized for her work in the field of immuno-oncology and her patient-first approach will bring an important perspective to our team as we initiate clinical studies for our lead program, KIN-2787," said Nima Farzan, CEO of Kinnate. "Helen is a passionate leader with an incredible track record of success in the biopharmaceutical industry. On behalf of the entire team, we look forward to drawing from her experience to support Kinnate's growth."

    Dr. Sabzevari is currently President and CEO of Precigen, Inc., a dedicated discovery and clinical stage biopharmaceutical company. At Precigen, Dr. Sabzevari is leading discovery and development of the next generation of gene and cell therapies using precision technology to unmet medical needs in the areas of immuno-oncology, autoimmune disorders, and infectious diseases.

    Prior to Precigen, Dr. Sabzevari was co-founder and chief scientific officer of Compass Therapeutics, a fully integrated drug discovery and development company focused on manipulating the immune system to treat human disease. Prior to Compass Therapeutics, Dr. Sabzevari was senior vice president of immuno-oncology at Merck Serono (a subsidiary of Merck KGaA, Darmstadt, Germany), where her pioneering efforts led to the foundation of Merck Serono's immuno-oncology translational innovation platform for developing and advancing therapies, including cancer vaccines, cancer stem cell treatments and approaches to reset the immune system so that it is primed to eliminate cancer cells. Prior to Merck Serono, Dr. Sabzevari led the Molecular Immunology Group at the Laboratory of Tumor Immunology and Biology at the US National Cancer Institute (LTIB-NCI), where she was focused on design, development and delivery of novel vaccines and immunotherapies for a range of human cancers.  

    Dr. Sabzevari has been author or senior author on over 40 scientific publications and has been the recipient of the Mass High Tech's Women to Watch Award, the PharmaVOICE 100 Award and the NIH Merit Award for major contributions to the field of cancer immunotherapy. Most recently, Dr. Sabzevari received the Society for Immunotherapy of Cancer (SITC) Team Science Award for her work on the NCI Cancer Immunotherapy Program Team. 

    Dr. Sabzevari received her Ph.D. in cell and molecular immunology and completed her postdoctoral work at the department of immunology at the Scripps Research Institute working on various immunotherapeutic modalities in the treatment of cancer and autoimmune diseases.

    "I am pleased to join the esteemed group of biopharma innovators and executives on the Kinnate Board of Directors. The work the company has done in developing a potential new generation of kinase inhibitor product candidates is exciting and may offer new treatment options for the many patients who are not benefiting from existing targeted cancer therapies," said Dr. Sabzevari. "Under Nima's leadership, Kinnate has successfully hit a number of important milestones in a short period of time, and I am looking forward to supporting them as they enter this important next phase of progress into the clinic."

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, the expected timing for our initiation of our clinical trials, the potential benefits and treatment indications of our product candidates and the continued advancement of our product candidates and progression of our pipeline.   Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  6. Experienced leaders bring substantial clinical research, regulatory, and operational expertise in the biopharmaceutical industry to the Kinnate team

    SAN FRANCISCO and SAN DIEGO, June 07, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the appointment of Neha Krishnamohan as Chief Financial Officer and Executive Vice President, Corporate Development, and the expansion of its leadership team.

    "Kinnate is entering a new phase of growth as we prepare to initiate a first-in-human trial of our lead candidate KIN-2787 and advance our additional pipeline…

    Experienced leaders bring substantial clinical research, regulatory, and operational expertise in the biopharmaceutical industry to the Kinnate team

    SAN FRANCISCO and SAN DIEGO, June 07, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the appointment of Neha Krishnamohan as Chief Financial Officer and Executive Vice President, Corporate Development, and the expansion of its leadership team.

    "Kinnate is entering a new phase of growth as we prepare to initiate a first-in-human trial of our lead candidate KIN-2787 and advance our additional pipeline programs through preclinical studies. With the appointment of Neha and our other new executives, we have added decades of collective expertise in building and operating both emerging and large clinical-stage biopharmaceutical companies to the Kinnate leadership team," said Nima Farzan, Chief Executive Officer of Kinnate. "I am pleased to welcome each of them to Kinnate and look forward to their leadership in driving the continued progress of our pipeline and advancing our mission of expanding access to targeted therapies for people living with hard-to-treat, genomically defined cancers."

    Ms. Krishnamohan joins Kinnate from Goldman Sachs where she worked for more than 12 years and most recently served as a vice president in the Healthcare Investment Banking Group and a member of the Mergers and Acquisitions (M&A) Group within the Investment Banking Division. Ms. Krishnamohan established herself as a senior leader in the healthcare coverage group, working with a variety of biopharmaceutical boards and management teams on a broad range of strategic financial matters, executing financings as well as leading M&A transactions. She has successfully executed over $100 billion in transactions in the biopharmaceutical, medical technology, and tools/diagnostics sectors. She holds a B.S.E in Biomedical Engineering and Economics from Duke University.

    "Kinnate is at an exciting inflection point in its path to becoming a global, clinical-stage biopharmaceutical company. I look forward to partnering with the management team and the board to advance Kinnate's continued growth through the scale-up of its strategic corporate finance operations and guide the company's corporate strategy," said Ms. Krishnamohan. "Having spent more than a decade advising and performing diligence on companies in the biopharmaceutical sector, I am extremely impressed with the Kinnate team and the progress that they have made in a short period of time advancing their differentiated pipeline."

    Kinnate has also announced the appointment of the following senior leaders:

    • Ken Kobayashi, M.D., Senior Vice President, Clinical Development, who was most recently Vice President, Early Oncology Development and Clinical Research at Pfizer
    • Jason Cox, Ph.D., Vice President, Medicinal Chemistry, who joins from Merck where he spent 16 years, most recently as Director, Medicinal Chemistry
    • Jason Hampson, Vice President, Head of Regulatory Affairs, who joins from Amgen where he spent 18 years, most recently as Director of Regulatory Affairs
    • David Madden, Vice President, Finance, who joins from Emergent BioSolutions where he was most recently Sr. Director, Finance
    • Clement Pimor, Vice President Strategy and Portfolio Management, who joins from AbbVie where he was Asset Strategy Leader for the cancer medicine IMBRUVICA
    • Barbara Warren, Vice President Human Resources, who was most recently an Executive Human Resource Consultant at Cedars-Sinai in Los Angeles

    For more information about Kinnate's leadership team, please visit www.kinnate.com/leadership.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the potential benefits of our drug discovery activities (including our preclinical studies), the expected timing for our initiation of our clinical trials, the potential benefits and treatment indications of our product candidates, the continued advancement of our product candidates and progression of our pipeline and the expected growth of our operations. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com

    A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/caaec9b0-2082-4c11-814a-ae17aa5d47d0



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  7. SAN FRANCISCO and SAN DIEGO, June 04, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced results from preclinical studies evaluating its lead RAF inhibitor candidate, KIN-2787. These data will be presented today during a virtual poster session at the 57th Annual Meeting of the American Society of Clinical Oncology (ASCO).

    KIN-2787, Kinnate's most advanced product candidate, is an orally available small molecule pan-RAF inhibitor being developed for the treatment of patients with lung cancer, melanoma, and other solid tumors. Unlike currently available…

    SAN FRANCISCO and SAN DIEGO, June 04, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced results from preclinical studies evaluating its lead RAF inhibitor candidate, KIN-2787. These data will be presented today during a virtual poster session at the 57th Annual Meeting of the American Society of Clinical Oncology (ASCO).

    KIN-2787, Kinnate's most advanced product candidate, is an orally available small molecule pan-RAF inhibitor being developed for the treatment of patients with lung cancer, melanoma, and other solid tumors. Unlike currently available treatments that target only Class I BRAF kinase mutations, Kinnate has designed KIN-2787 to target Class II and Class III BRAF mutations, where it would be a first-line targeted therapy, in addition to covering Class I BRAF mutations. The U.S. Food and Drug Administration (FDA) has cleared Kinnate's Investigational New Drug (IND) application for KIN-2787 and the company anticipates initiating a first-in-human Phase 1 clinical trial of the candidate in patients with mutant BRAF-driven solid tumors in mid-2021.

    "These data are important, early signals of the potential anti-tumor activity of KIN-2787 and support our IND application recently cleared by the FDA," said Eric Murphy, PhD, Chief Scientific Officer, and co-founder of Kinnate. "Our approach targets dimer signaling in specific patient populations with BRAF mutations while minimizing MAPK paradoxical activation. KIN-2787 shows pronounced in vitro and in vivo activity against human cancers driven by Class I, II and III BRAF alterations, and these results support our phase 1 clinical trial initiating shortly in these defined molecular subtypes."

    The poster presentation, delivered by Aleksandra Franovic, PhD, Senior Director of Translational Medicine at Kinnate, highlights data which show that treatment with KIN-2787 resulted in exposure-dependent inhibition of MEK-ERK phosphorylation and was accompanied by the successful suppression of MAPK transcriptional targets at the RNA and protein level. High selectivity was displayed for all three RAF family kinases in screens evaluating its activity against more than 600 kinases. Due to potent dimer inhibition, KIN-2787 did not demonstrate significant paradoxical activation in these studies. Twice daily (BID) dosing was well-tolerated and led to prolonged target coverage and a trend towards more frequent and deeper tumor responses in vivo.

    Kinnate's poster presentation (Abstract #3116), titled "The next-generation pan-RAF inhibitor, KIN-2787, is active in class II and class III BRAF Mutant models," will be available for on-demand viewing at 09:00AM ET today and can be accessed via: https://conferences.asco.org/am/attend.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the expected timing for our initiation of our clinical trials and the potential benefits and treatment indications of our product candidates. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance, or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  8. SAN FRANCISCO and SAN DIEGO, May 25, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Nima Farzan, Chief Executive Officer of Kinnate, will provide a company overview at the Goldman Sachs 42nd Annual Global Healthcare Conference, being held virtually from June 8-11, 2021.

    Event: Goldman Sachs 42nd Annual Global Healthcare Conference
    Location: Virtual
    Date: Thursday, June 10, 2021
    Time: 2:10 PM ET/ 11:10 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the Goldman Sachs…

    SAN FRANCISCO and SAN DIEGO, May 25, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Nima Farzan, Chief Executive Officer of Kinnate, will provide a company overview at the Goldman Sachs 42nd Annual Global Healthcare Conference, being held virtually from June 8-11, 2021.

    Event: Goldman Sachs 42nd Annual Global Healthcare Conference

    Location: Virtual

    Date: Thursday, June 10, 2021

    Time: 2:10 PM ET/ 11:10 AM PT

    Members of the Kinnate management team will also host investor meetings during the conference.

    A live webcast of the Goldman Sachs presentation will be available in the Investors and Media section of the Kinnate website at www.kinnate.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, Kinnate's expected participation at investor conferences and meetings. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  9. KIN-2787 is the company's RAF inhibitor candidate for patients with mutant BRAF-driven solid tumors

    Planned initiation of Phase 1 clinical trial for KIN-2787 in mid-2021

    Ended the quarter with cash and cash equivalents and investments of $383.1 million

    Closed $35 million Series A financing of Chinese joint venture in May 2021

    SAN FRANCISCO and SAN DIEGO, May 17, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that the U.S Food and Drug Administration (FDA) has cleared the company's Investigational New Drug (IND) application for KIN-2787 and…

    KIN-2787 is the company's RAF inhibitor candidate for patients with mutant BRAF-driven solid tumors

    Planned initiation of Phase 1 clinical trial for KIN-2787 in mid-2021

    Ended the quarter with cash and cash equivalents and investments of $383.1 million

    Closed $35 million Series A financing of Chinese joint venture in May 2021

    SAN FRANCISCO and SAN DIEGO, May 17, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that the U.S Food and Drug Administration (FDA) has cleared the company's Investigational New Drug (IND) application for KIN-2787 and also announced financial results for the quarter ended March 31, 2021. Kinnate expects to initiate a first-in-human Phase 1 clinical trial of KIN-2787 in patients with mutant BRAF-driven solid tumors in mid-2021.

    "In the three years since our founding, Kinnate has consistently hit key milestones essential to our mission of delivering new therapies to patients with difficult-to-treat, genomically-defined cancers. The FDA's clearance of our KIN-2787 IND marks another major achievement for the company and demonstrates the important progress we are making in our transition to becoming a clinical-stage company," said Nima Farzan, Chief Executive Officer of Kinnate. "As we prepare for our first-in-human trial of KIN-2787 later this year, we are also pleased with the rapid advance of our lead FGFR inhibitor candidate, KIN-3248, which we believe may offer a new option for certain patients with cancers like urothelial tumors or intrahepatic cholangiocarcinoma. We anticipate a first half of 2022 IND filing for KIN-3248."

    The Phase 1 trial will evaluate the safety, tolerability, pharmacokinetics and anti-cancer activity of KIN-2787 in cancer patients with mutant BRAF-driven solid tumors.  The dose escalation portion (Part A) of the trial will determine the recommended dose and schedule of KIN-2787 for further evaluation in patients with BRAF mutations.  The dose expansion phase (Part B) of the trial will assess the safety and efficacy of KIN-2787 at the recommended dose and schedule in patients with cancers driven by BRAF Class II or III mutations, including lung cancer, melanoma and other selected adult solid tumors.

    Recent Business Highlights and Corporate Update:

    • In our RAF program, we filed an IND in April 2021 with the FDA to study KIN-2787 in patients with mutant BRAF-driven solid tumors. The FDA cleared the IND in May 2021 and we anticipate initiating a Phase 1 clinical trial for KIN-2787 in mid-2021.  KIN-2787, our most advanced product candidate, is a RAF inhibitor we are developing for the treatment of patients with lung cancer, melanoma and other solid tumors. Unlike currently available treatments that target only Class I BRAF kinase mutations, we have designed KIN-2787 to target Class II and Class III BRAF mutations, where it would be a first-line targeted therapy, in addition to covering Class I BRAF mutations.
    • In May 2021 we closed a $35 million Series A financing of a joint venture in China. Established with OrbiMed Asia Partners, OrbiMed Private Investments and Foresite Capital, the joint venture will be headquartered in Shanghai and the financing will enable the potential development and commercialization by the joint venture of certain Kinnate targeted oncology product candidates across Greater China (mainland China, Hong Kong, Taiwan, and Macau). Kinnate Biopharma will be the majority shareholder in the joint venture. The company has also announced that veteran biopharmaceutical industry executive Wenn Sun, Ph.D., has been appointed as the joint venture's Executive Chair.
    • Data from pre-clinical studies of KIN-2787 have been selected for poster presentation at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, which will be held virtually June 4-8, 2021. The data to be presented at the ASCO annual meeting was derived from pre-clinical studies evaluating the efficacy and tolerability of KIN-2787 in vitro and in vivo in BRAF mutation-driven human cancer models.
    • In our FGFR program, we selected KIN-3248 as our lead FGFR inhibitor candidate for the treatment of intrahepatic cholangiocarcinoma and urothelial carcinoma and initiated GLP-toxicity studies of KIN-3248.  Our FGFR candidates are designed to address clinically observed genomic alterations in FGFR2 and FGFR3 that drive resistance to current therapies. We anticipate filing an IND for KIN-3248 with the FDA in the first half of 2022 and, subject to our planned IND submission taking effect, initiating a Phase 1 clinical trial for KIN-3248 in the first half of 2022.
    • We continued to advance a number of other small molecule research programs, including a CDK12 inhibitor in our KIN004 program to target the treatment of ovarian carcinoma, triple-negative breast cancer and metastatic castration-resistant prostate cancer.
    • We expanded our organization to 41 full-time employees at March 31, 2021, of which 30 were engaged in research and development activities.

    First Quarter 2021 Financial Results

    • First quarter net loss for 2021 was $17.5 million, compared to $3.9 million for the same period in 2020. 
    • First quarter research and development expenses for 2021 were $12.7 million, compared to $3.2 million for the same period in 2020.
    • First quarter general and administrative expenses for 2021 were $4.8 million, compared to $1.0 million for the same period in 2020.
    • As of March 31, 2021, the total of cash and cash equivalents and investments was $383.1 million. 

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the potential benefits of our drug discovery activities, the expected timing for our regulatory filings and initiation of our clinical trials and the potential benefits and treatment indications of our product candidates. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2021 that we are concurrently filing with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



     
    Kinnate Biopharma Inc.
    Condensed Balance Sheets
    (in thousands, except share and par value amounts)
    (Unaudited)
        
        
     March 31, 2021 December 31, 2020
    Assets   
    Current assets:   
    Cash and cash equivalents$182,389  $365,462 
    Short-term investments 65,808   31,398 
    Prepaid expenses and other current assets 2,975   3,343 
    Total current assets 251,172   400,203 
    Property and equipment, net 283   368 
    Long-term investments 134,910   - 
    Total assets$386,365  $400,571 
        
    Liabilities and Stockholders' Equity    
    Current liabilities:   
    Accounts payable$3,212  $3,940 
    Accrued expenses 4,581   3,364 
    Total current liabilities 7,793   7,304 
    Commitments and contingencies   
    Stockholders' equity:   
    Preferred stock, $0.0001 par value; 200,000,000 shares authorized   
    at March 31, 2021 and December 31, 2020; 0 shares outstanding   
    at March 31, 2021 and December 31, 2020 -   - 
    Common stock, $0.0001 par value; 1,000,000,000 shares authorized   
    at March 31, 2021 and December 31, 2020; 43,477,439 shares   
    issued and outstanding at March 31, 2021 and December 31, 2020 4   4 
    Additional paid-in capital 449,394   446,601 
    Accumulated other comprehensive loss (40)  (9)
    Accumulated deficit (70,786)  (53,329)
    Total stockholders' equity 378,572   393,267 
    Total liabilities and stockholders' equity$386,365  $400,571 
        

     

     
    Kinnate Biopharma Inc.
    Condensed Statements of Operations and Comprehensive Loss
    (Unaudited)
    (in thousands, except share and per share amounts)
        
     Three Months Ended March 31,
      2021   2020 
        
    Operating expenses:   
    Research and development$12,666  $3,198 
    General and administrative (includes related party amounts of $0 and $92, respectively) 4,815   955 
    Total operating expenses 17,481   4,153 
    Loss from operations (17,481)  (4,153)
    Other income:   
    Interest income 403   212 
    Other (expense) income, net (379)  - 
    Total other income, net 24   212 
    Net loss (17,457)  (3,941)
    Unrealized loss on investments (31)  - 
    Comprehensive loss$(17,488) $(3,941)
    Weighted-average shares outstanding, basic and diluted 43,477,439   3,672,446 
    Net loss per share, basic and diluted$(0.40) $(1.07)



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    • Financing led by OrbiMed Asia Partners, with participation from OrbiMed Private Investments and Foresite Capital

    • The joint venture will have exclusive license to develop and commercialize Kinnate's currently most advanced kinase inhibitor candidates in Greater China

    • Veteran biopharmaceutical industry executive Wenn Sun, Ph.D. has been named as Executive Chair

    SAN FRANCISCO and SAN DIEGO, May 13, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced the closing of a $35 million Series A financing for a joint venture in China. Established with OrbiMed Asia Partners…

    • Financing led by OrbiMed Asia Partners, with participation from OrbiMed Private Investments and Foresite Capital



    • The joint venture will have exclusive license to develop and commercialize Kinnate's currently most advanced kinase inhibitor candidates in Greater China



    • Veteran biopharmaceutical industry executive Wenn Sun, Ph.D. has been named as Executive Chair

    SAN FRANCISCO and SAN DIEGO, May 13, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, announced the closing of a $35 million Series A financing for a joint venture in China. Established with OrbiMed Asia Partners, OrbiMed Private Investments and Foresite Capital, the joint venture will be headquartered in Shanghai and enable the potential development and commercialization of certain Kinnate targeted oncology product candidates across Greater China (mainland China, Hong Kong, Taiwan, and Macau). Kinnate Biopharma will be the majority shareholder in the joint venture. The company has also announced that veteran biopharmaceutical industry executive Wenn Sun, Ph.D., has been appointed as the joint venture's Executive Chair.

    "Establishing operations in China creates a tremendous opportunity for Kinnate to build its global footprint and further advance our mission of expanding access to innovative targeted therapies for people battling cancer," said Nima Farzan, President and CEO of Kinnate Biopharma Inc. "OrbiMed Private Investments and Foresite Capital have been important partners in the growth of Kinnate and we are pleased to now have the support of OrbiMed Asia Partners who led this financing and brings tremendous expertise and connections in China to this new joint venture. I look forward to working with this leading team of investors and Dr. Sun to make precision medicine a reality for more people in Greater China, which is one of the world's largest healthcare markets."

    The initial focus of the joint venture is on advancing the development of KIN-2787 for the Greater China market. KIN-2787 is a Rapidly Accelerated Fibrosarcoma (RAF) inhibitor candidate being developed for the treatment of patients with lung cancer, melanoma, and other solid tumors. The joint venture will also pursue development of KIN-3248 for the Chinese market. KIN-3248 is a Fibroblast Growth Factor Receptors (FGFR) inhibitor candidate for the treatment of patients with intrahepatic cholangiocarcinoma (ICC), a cancer of the bile ducts in the liver, and urothelial carcinoma (UC), a cancer of the bladder lining. The joint venture, which will be subsequently named, has an exclusive license to one other Kinnate program and may also obtain rights to develop certain other new product candidates in Greater China from the Kinnate pipeline, as well as other third-party product candidates in China and other geographies.

    "Since its founding, Kinnate has demonstrated impressive scientific discipline and exceptional execution in building a robust pipeline of targeted therapies for hard-to-treat cancers," said Steven D. Wang, Ph.D., CFA, Partner and Senior Managing Director, OrbiMed Asia Partners. "We are pleased to join them in establishing this joint venture in China and look forward to working closely with Dr. Sun and our other regional colleagues in bringing these potentially life-saving therapies to more patients."

    Dr. Sun is the Founder and President of Precision Medicine Asia (PREMIA), an oncology-focused clinical genomic data company she founded in 2018. Previously, she was the Founder and Managing Partner for OxOnc Development, a venture company that, along with Pfizer Oncology, co-developed XALKORI in patients with ROS1 genetic alterations in Asia, including China. Dr. Sun also served as Head of Strategic Alliances for GSK Oncology, and helped build its alliances with various clinical research networks around the world. In 2003, in collaboration with the National Comprehensive Cancer Network (NCCN), she helped introduce the NCCN Guidelines to China. Dr. Sun was appointed Chief Business Development Officer at the Lurie Cancer Center of Northwestern University after her post-doctoral fellowship at University of Wisconsin-Madison.

    "I am honored to join the Kinnate team and lead the joint venture's efforts to help the patients in China for whom no genomically-targeted therapies exist or for which a resistance to targeted treatments has evolved," said Dr. Sun. "KIN-2787 has already demonstrated very promising results in pre-clinical studies and presents a significant opportunity to help address the tremendous demand for more effective cancer therapies across Greater China."

    About Kinnate Biopharma Inc.

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the potential benefits and opportunities created by our joint venture, the future activities of our joint venture, and the potential benefits of our drug discovery activities and treatment indications of our product candidates (including for patients in China). Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Annual Report on Form 10-K for the fiscal year ended December 31, 2020 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  10. Data highlights pre-clinical activity of KIN-2787 in Class II and Class III BRAF-mutant models

    Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that data from pre-clinical studies of its RAF inhibitor candidate, KIN-2787, have been selected for a poster presentation at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting. The ASCO meeting will be held virtually from June 4-8, 2021.

    "As we advance towards the initiation of clinical studies for our lead RAF inhibitor program, we are honored to be selected by the ASCO Scientific Program Committee to present…

    Data highlights pre-clinical activity of KIN-2787 in Class II and Class III BRAF-mutant models

    Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that data from pre-clinical studies of its RAF inhibitor candidate, KIN-2787, have been selected for a poster presentation at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting. The ASCO meeting will be held virtually from June 4-8, 2021.

    "As we advance towards the initiation of clinical studies for our lead RAF inhibitor program, we are honored to be selected by the ASCO Scientific Program Committee to present findings from our pre-clinical studies of KIN-2787 at this year's Annual Meeting," said Eric Murphy, Ph.D., co-founder and Chief Scientific Officer of Kinnate. "We are enthusiastic about the advancement of KIN-2787 to address actionable RAF mutations in molecular subtypes that are not addressed by existing drugs or are resistant to available standard-of-care therapies."

    Oncogenic BRAF gene alterations, leading to aberrantly activated BRAF monomers (Class I mutations) or dimers (Class II and Class III mutations), are observed in approximately 6% of all human cancers. First-generation BRAF inhibitors targeting Class I BRAF mutants, including dabrafenib, encorafenib, and vemurafenib, provide significant clinical benefit to patients with BRAF V600 mutation-driven melanoma and select solid tumors as monotherapies or in combination with other targeted therapies. The currently approved BRAF inhibitors have not, however, proven to be effective in patients with Class II or III BRAF alterations. For example, approximately 62% of BRAF mutations in non-small-cell lung carcinoma (NSCLC) and approximately 21% of BRAF mutations in melanoma are identified as Class II and Class III BRAF mutations where the currently approved Class I inhibitors are not effective.

    The data to be presented at the ASCO annual meeting were derived from pre-clinical studies evaluating the efficacy and tolerability of KIN-2787 in vitro and in vivo in BRAF mutation-driven human cancer models. A phase 1 dose escalation and expansion clinical trial evaluating the safety and efficacy of KIN-2787 monotherapy in patients with advanced or metastatic solid tumors harboring BRAF gene alterations, including Class II and III mutations, is expected to initiate in 2021.

    Additional information on the ASCO annual meeting can be found online at: https://meetings.asco.org. Per ASCO's Embargo & Release Information, complete abstracts will be released to the public on ASCO's Meeting Library, https://meetinglibrary.asco.org, at 5:00 p.m. ET on May 19, 2021.

    Kinnate's poster presentation will become available for on-demand viewing beginning Friday, June 4, 2021 at 9:00 a.m. ET, and can be accessed at: https://conferences.asco.org/am/attend.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements include, without limitation, statements regarding the expected timing for initiation of our clinical trials and the potential benefits and treatment indications of our product candidates. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Annual Report on Form 10-K for the fiscal year ended December 31, 2020 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

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  11. SAN FRANCISCO and SAN DIEGO, April 30, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Dr. Stephen Kaldor, one of the company's co-founders, is not being nominated for re-election to the company's Board of Directors when his term expires at the company's 2021 annual meeting of stockholders to be held June 11, 2021. Dr. Kaldor plans to focus on his duties as chairman and co-founder of a new biopharmaceutical start-up.

    "Steve is an incredible entrepreneur and chemist and was a driving force in the founding and early progress of Kinnate's…

    SAN FRANCISCO and SAN DIEGO, April 30, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Dr. Stephen Kaldor, one of the company's co-founders, is not being nominated for re-election to the company's Board of Directors when his term expires at the company's 2021 annual meeting of stockholders to be held June 11, 2021. Dr. Kaldor plans to focus on his duties as chairman and co-founder of a new biopharmaceutical start-up.

    "Steve is an incredible entrepreneur and chemist and was a driving force in the founding and early progress of Kinnate's pipeline of kinase inhibitors. We have benefited from his 25 years of experience building companies, and on behalf of the other directors and the entire Kinnate team we wish him all the best in his new endeavors," said Nima Farzan, Chief Executive Officer of Kinnate.

    "Under Nima's leadership, Kinnate has made tremendous progress and has entered a new phase of growth as a public company. This is the right time for me to transition from Kinnate and devote more time to my new venture," said Dr. Kaldor. "The talented team Nima has built is well equipped to realize the company's mission of expanding targeted therapy access to underserved populations of people fighting cancer. It has been a pleasure to see Kinnate succeed and an honor to serve on the company's Board of Directors. I wish the entire team success as they continue to advance towards the clinic."

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements, include, without limitation, statements regarding the potential benefits of our drug discovery activities, the expected initiation of our clinical trials, and the potential benefits and treatment indications of our product candidates. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Annual Report on Form 10-K for the fiscal year ended December 31, 2020 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



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  12. Completed recent IPO, raising $276MM in gross proceeds to fund kinase inhibitors for genomically defined cancers

    Progress towards IND filing for KIN-2787, our RAF inhibitor candidate, in the first half of 2021 and initiating a Phase 1 clinical trial later in the year remains on track

    Selected KIN-3248 as our lead FGFR inhibitor candidate; anticipate IND filing in the first half of 2022

    SAN FRANCISCO and SAN DIEGO, March 29, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced financial results for the full year ended December 31, 2020…

    Completed recent IPO, raising $276MM in gross proceeds to fund kinase inhibitors for genomically defined cancers

    Progress towards IND filing for KIN-2787, our RAF inhibitor candidate, in the first half of 2021 and initiating a Phase 1 clinical trial later in the year remains on track

    Selected KIN-3248 as our lead FGFR inhibitor candidate; anticipate IND filing in the first half of 2022

    SAN FRANCISCO and SAN DIEGO, March 29, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced financial results for the full year ended December 31, 2020.

    "Since completing our IPO last year, we entered 2021 well-funded to advance the development of our lead targeted therapy RAF and FGFR programs towards the clinic," said Nima Farzan, Chief Executive Officer of Kinnate Biopharma. "We are pleased to be on track with our stated goals of filing an investigational new drug application for KIN-2787, our RAF inhibitor candidate, in the first half of 2021 and initiating a Phase 1 clinical trial later in the year. Additionally, our FGFR inhibitor KIN-3248 candidate is progressing towards an IND filing and Phase I clinical trial in the first half of 2022. We believe our Kinnate drug discovery engine has the ability to identify product candidates with the potential to overcome the limitations of current targeted oncology therapeutics."

    Recent Business Highlights and Corporate Update:

    • In December 2020, completed a successful initial public offering, raising $276.0 million in aggregate gross proceeds (before deducting underwriting discounts and commissions and estimated offering expenses) and listed on The Nasdaq Global Select Market.
    • Remain on track for an Investigational New Drug (IND) filing for KIN-2787 in the first half of 2021 following encouraging pre-IND feedback from the U.S. Food and Drug Administration (FDA). KIN-2787, our most advanced product candidate, is a RAF inhibitor we are developing for the treatment of patients with lung cancer, melanoma and other solid tumors. Unlike currently available treatments that target only Class I BRAF kinase mutations, we have designed KIN-2787 to target Class II and Class III BRAF mutations, where it would be a first-line targeted therapy, in addition to covering Class I BRAF mutations.
    • In our KIN003 program we have selected KIN-3248 as our lead FGFR inhibitor candidate for the treatment of patients with intrahepatic cholangiocarcinoma and urothelial carcinoma. Our FGFR candidates are designed to address clinically observed genomic alterations in FGFR2 and FGFR3 that drive resistance to current therapies. We anticipate filing an IND for KIN-3248 with the FDA in the first half of 2022.
    • Our RAF and FGFR candidates have demonstrated proof of concept in preclinical models and, subject to our planned IND submissions taking effect, we anticipate initiating a Phase 1 clinical trial for KIN-2787 in 2021 and an additional Phase 1 clinical trial for KIN-3248 in the first half of 2022.
    • Continued to advance a number of other small molecule research programs, including a CDK12 inhibitor in our KIN004 program to target the treatment of ovarian carcinoma, triple-negative breast cancer and metastatic castration-resistant prostate cancer.
    • Expanded organization with 31 full-time employees at December 31, 2020, of which 24 were engaged in research and development activities.

    Full-Year 2020 Financial Results

    • Full year net loss for 2020 was $35.8 million, compared to $12.0 million in 2019.
    • Full year research and development expenses for 2020 were $29.2 million, compared to $9.0 million in 2019.
    • Full year general and administrative expenses for 2020 increased to $6.8 million, compared to $3.1 million in 2019.
    • As of December 31, 2020, the total of cash and cash equivalents and short-term investments was $396.9 million.

    About Kinnate Biopharma Inc.

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements that involve substantial risks and uncertainties. These forward-looking statements, include, without limitation, statements regarding the potential benefits of our drug discovery activities, the expected timing for our regulatory filings and initiation of clinical trials, the potential benefits and treatment indications of our product candidates, and the adequacy of our current financial resources. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are also intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements are subject to a number of risks, uncertainties, assumptions and other factors, including risks related to operating as a preclinical-stage biopharmaceutical company with a limited operating history; our ability to raise additional capital to finance our operations; our ability to discover, advance through the preclinical and clinical development of, obtain regulatory approval for and commercialize our product candidates; the novel approach we are taking to discover and develop drugs; our ability to timely file and obtain approval of investigational new drug applications for our planned clinical trials; the potential for any clinical trial results to differ from our preclinical trial results; negative impacts of the COVID-19 pandemic on our business, including planned clinical trials and ongoing and planned preclinical trials; competition in our industry; regulatory developments in the United States and other countries; our ability to attract, hire and retain highly skilled executive officers and employees; difficulties in managing our growth; our ability to protect our intellectual property; reliance on third parties to conduct our preclinical studies and any future clinical trials, and to manufacture our product candidates; general economic and market conditions; and other risks.

    These and other risks, uncertainties, assumptions and other factors are further described under the heading "Risk Factors" in our Annual Report on Form 10-K for the fiscal year ended December 31, 2020 that we have filed with the Securities and Exchange Commission (the "SEC"), as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Our forward-looking statements speak only as of the date of this release, and except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason in the future.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com

     
    Kinnate Biopharma Inc.
    Balance Sheets
    (in thousands, except share and par value amounts)
        
     December 31,
      2020   2019 
        
    Assets   
    Current assets:   
    Cash and cash equivalents$365,462  $76,453 
    Short-term investments 31,398   - 
    Related party receivables, net (See Note 9) -   973 
    Prepaid expenses and other current assets 3,343   25 
    Total current assets 400,203   77,451 
    Property and equipment, net 368   154 
    Total assets$400,571  $77,605 
        
    Liabilities, Convertible Preferred Stock and Stockholders' Equity (Deficit)   
    Current liabilities:   
    Accounts payable$3,940  $956 
    Accrued expenses 3,364   989 
    Total current liabilities 7,304   1,945 
    Commitments and contingencies (See Note 11)   
    Convertible preferred stock:   
    Series A convertible preferred stock, $0.0001 par value;   
    0 and 7,762,733 shares authorized at December 31, 2020 and 2019, respectively;   
    0 and 7,762,727 shares issued and outstanding at December 31, 2020 and   
    2019, respectively; aggregate liquidation preference of $0 and $19,167 at   
    December 31, 2020 and 2019, respectively -   18,942 
    Series B convertible preferred stock, $0.0001 par value;   
    0 and 9,705,185 share authorized at December 31, 2020 and 2019, respectively;   
    0 and 9,705,182 shares issued and outstanding at December 31, 2020 and   
    2019, respectively; aggregate liquidation preference of $0 and $74,500 at   
    December 31, 2020 and 2019, respectively -   74,204 
    Stockholders' equity (deficit):   
    Preferred stock, $0.0001 par value; 200,000,000 and 0 shares authorized   
    at December 31, 2020 and 2019, respectively; 0 shares outstanding   
    at December 31, 2020 and 2019, respectively -   - 
    Common stock, $0.0001 par value; 1,000,000,000 and 26,914,696   
    shares authorized at December 31, 2020 and 2019, respectively;   
    43,477,439 and 3,665,020 shares issued and outstanding at   
    December 31, 2020 and 2019, respectively 4   - 
    Additional paid-in capital 446,601   82 
    Accumulated other comprehensive loss (9)  - 
    Accumulated deficit (53,329)  (17,568)
    Total stockholders' equity (deficit) 393,267   (17,486)
    Total liabilities, convertible preferred stock and stockholders' equity (deficit)$400,571  $77,605 
        



    Kinnate Biopharma Inc.
    Statements of Operations and Comprehensive Loss
    (in thousands, except share and per share amounts)
        
     Years Ended December 31,
      2020   2019 
        
    Operating expenses:   
    Research and development (includes related party amounts of $0 and $2,301, respectively)$29,237  $8,955 
    General and administrative (includes related party amounts of $92 and $2,609, respectively) 6,764   3,057 
    Total operating expenses 36,001   12,012 
    Loss from operations (36,001)  (12,012)
    Other income:   
    Interest income 245   43 
    Other (expense) income, net (5)  - 
    Total other income 240   43 
    Net loss (35,761)  (11,969)
    Gain on extinguishment of Series A convertible preferred stock -   2,031 
    Net loss attributable to common stockholders$(35,761) $(9,938)
    Unrealized loss on short-term investments (9)  - 
    Comprehensive loss$(35,770) $(9,938)
    Weighted-average shares outstanding, basic and diluted 6,767,591   3,659,456 
    Net loss attributable to common stockholders per share, basic and diluted$(5.28) $(2.72)
        



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  13. SAN FRANCISCO and SAN DIEGO, March 19, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that it will be added to the Russell 2000® Index as part of the planned first quarter IPO additions scheduled to join the Russell US Indexes after US equity markets close on March 19, 2021.  

    "Kinnate's inclusion in the Russell 2000 Index marks an exciting milestone following our successful IPO in December 2020 and is a testament to the incredible progress we have made in building a pipeline of targeted therapy candidates for underserved cancer populations…

    SAN FRANCISCO and SAN DIEGO, March 19, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that it will be added to the Russell 2000® Index as part of the planned first quarter IPO additions scheduled to join the Russell US Indexes after US equity markets close on March 19, 2021.  

    "Kinnate's inclusion in the Russell 2000 Index marks an exciting milestone following our successful IPO in December 2020 and is a testament to the incredible progress we have made in building a pipeline of targeted therapy candidates for underserved cancer populations," said Nima Farzan, Chief Executive Officer of Kinnate Biopharma. "We are pleased to be part of the Russell Indexes and look forward to telling our story to a broader audience of investors and other key stakeholders."

    Russell indexes are widely used by investment managers and institutional investors for index funds and as benchmarks for active investment strategies. The Russell 2000® Index measures the performance of the small-cap segment of the U.S. equity market. The index is a subset of the Russell 3000® Index and represents approximately 10 percent of the total market capitalization of that index. Approximately $9 trillion in assets are benchmarked against Russell's U.S. indexes which are part of FTSE Russell, a leading global index provider.

    About Kinnate

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements, as that term is defined in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, without limitation, Kinnate's product candidate pipeline and future investor and other stakeholder meetings. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties, assumptions and other factors described under the heading "Risk Factors" in our Form S-1 Registration Statement that we have filed with the Securities and Exchange Commission (the "SEC") and that became effective on December 2, 2020, as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance, or achievements. Except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason after the date of this press release.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    203-918-4347

    colin@bioscribe.com



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  14. SAN FRANCISCO and SAN DIEGO, Feb. 11, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Nima Farzan, Chief Executive Officer of Kinnate, will provide a company overview at the following upcoming investor conferences in February:

    • Event: Goldman Sachs West Coast Biotech Bus Tour
      Location: Virtual
      Date: Monday, February 22, 2021
      Time: 4:00-4:50 PM ET/1:00-1:50 PM PT
    • Event: 10th Annual SVB Leerink Global Healthcare Conference
      Location: Virtual
      Date: Wednesday, February 24, 2021
      Time: 4:20 PM ET/1:20PM PT

    Members of the Kinnate management team will also…

    SAN FRANCISCO and SAN DIEGO, Feb. 11, 2021 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced that Nima Farzan, Chief Executive Officer of Kinnate, will provide a company overview at the following upcoming investor conferences in February:

    • Event: Goldman Sachs West Coast Biotech Bus Tour

      Location: Virtual

      Date: Monday, February 22, 2021

      Time: 4:00-4:50 PM ET/1:00-1:50 PM PT
    • Event: 10th Annual SVB Leerink Global Healthcare Conference

      Location: Virtual

      Date: Wednesday, February 24, 2021

      Time: 4:20 PM ET/1:20PM PT

    Members of the Kinnate management team will also host investor meetings during the SVB Leerink Global Healthcare Conference.

    A live webcast of the SVB Leerink presentation will be available in the Investors and Media section of the Kinnate website at www.kinnate.com. A webcast replay will also be available on this website shortly after conclusion of the event for 30 days.

    About Kinnate Biopharma Inc.

    Kinnate is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors. For more information, please visit www.kinnate.com.

    Forward Looking Statements

    This press release contains forward-looking statements, as that term is defined in Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, without limitation, Kinnate's expected participation at investor conferences. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. Such expectations and projections may never materialize or may prove to be incorrect. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties, assumptions and other factors described under the heading "Risk Factors" in our Form S-1 Registration Statement that we have filed with the Securities and Exchange Commission (the "SEC") and that became effective on December 2, 2020, as well as in our subsequent filings we make with the SEC. New risk factors emerge from time to time and it is not possible for our management to predict all risk factors, nor can we assess the impact of all factors on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in, or implied by, any forward-looking statements. Investors should not rely upon forward-looking statements as predictions of future events. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. Except as required by law, we undertake no obligation to update publicly any forward-looking statements for any reason after the date of this press release.

    Contacts:

    Investors:

    Patti Bank

    Westwicke, an ICR Company

    415-513-1284

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



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  15. SAN FRANCISCO and SAN DIEGO, Dec. 07, 2020 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the closing of its initial public offering of 13,800,000 shares of its common stock, which includes the exercise in full of the underwriters' option to purchase 1,800,000 additional shares of its common stock, at a price to the public of $20.00 per share. Including the option exercise, the aggregate gross proceeds from the offering were $276.0 million, before deducting underwriting discounts and commissions and estimated offering expenses. All of the shares…

    SAN FRANCISCO and SAN DIEGO, Dec. 07, 2020 (GLOBE NEWSWIRE) -- Kinnate Biopharma Inc. (NASDAQ:KNTE) ("Kinnate"), a biopharmaceutical company focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers, today announced the closing of its initial public offering of 13,800,000 shares of its common stock, which includes the exercise in full of the underwriters' option to purchase 1,800,000 additional shares of its common stock, at a price to the public of $20.00 per share. Including the option exercise, the aggregate gross proceeds from the offering were $276.0 million, before deducting underwriting discounts and commissions and estimated offering expenses. All of the shares were offered by Kinnate. The shares began trading on The Nasdaq Global Select Market on December 3, 2020, under the symbol "KNTE."

    Goldman Sachs & Co. LLC, SVB Leerink LLC and Piper Sandler & Co. acted as joint book-running managers for the offering. Wedbush PacGrow acted as lead manager for the offering.

    Registration statements relating to these securities have been filed with the Securities and Exchange Commission and became effective on December 2, 2020. The offering was made only by means of a prospectus. Copies of the final prospectus may be obtained from: Goldman Sachs & Co. LLC, Attention: Prospectus Department, 200 West Street, New York, NY 10282, by telephone at (866) 471-2526, or by email at Prospectus-ny@ny.email.gs.com; SVB Leerink LLC, Attention: Syndicate Department, One Federal Street, 37th Floor, Boston, MA 02110, by telephone at (800) 808-7525, ext. 6132, or by email at syndicate@svbleerink.com; or Piper Sandler & Co., 800 Nicollet Mall, J12S03, Minneapolis, MN 55402, Attention: Prospectus Department, by telephone at (800) 747-3924, or by email at prospectus@psc.com.

    This press release does not constitute an offer to sell or a solicitation of an offer to buy these securities, nor will there be any sale of these securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful before registration or qualification under the securities laws of that state or jurisdiction.

    About Kinnate Biopharma Inc.

    Kinnate Biopharma is focused on the discovery and development of small molecule kinase inhibitors for difficult-to-treat, genomically defined cancers. Kinnate's mission is to expand the reach of targeted therapeutics by developing products for underserved populations. Kinnate utilizes its deep expertise in structure-based drug discovery, translational research, and patient-driven precision medicine, which it refers to as the Kinnate Discovery Engine, to develop targeted therapies. Based in San Francisco and San Diego, California, the Kinnate team is composed of drug discovery experts supported by a distinguished group of scientific advisors.

    For more information, please contact:

    Investors:

    investors@kinnate.com

    Media:

    Colin Sanford

    colin@bioscribe.com



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