JNCE Jounce Therapeutics Inc.

7.79
-0.06  -1%
Previous Close 7.85
Open 7.79
52 Week Low 5.03
52 Week High 14.84
Market Cap $399,097,506
Shares 51,232,029
Float 36,143,173
Enterprise Value $197,373,427
Volume 1,484,382
Av. Daily Volume 402,829
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Upcoming Catalysts

Drug Stage Catalyst Date
Vopratelimab and JTX-4014 - (SELECT)
Second-line non-small cell lung cancer (NSCLC) patients
Phase 2
Phase 2
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Drug Pipeline

Drug Stage Notes
Vopratelimab
Solid tumors - Cancer
Phase 1/2
Phase 1/2
Phase 1/2 data to be presented at ASCO-SITC Clinical Immuno-Oncology Symposium Annual Meeting on February 6, 2020.
JTX-8064 (INNATE)
Solid tumors
Phase 1
Phase 1
Phase 1 tumor-specific monotherapy and pimivalimab combination expansion cohorts to commence 3Q 2021.
Vopratelimab and YERVOY (ipilimumab) - EMERGE
Non-small cell lung cancer and bladder cancer
Phase 2
Phase 2
Phase 2 interim analysis noted the trial will not meet pre-specified interim criteria for continuation of enrollment - November 2, 2020.

Latest News

  1. CAMBRIDGE, Mass., Sept. 15, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced the appointment of former chief executive officer of Constellation Pharmaceuticals and former Jounce chief business officer, Jigar Raythatha, to its board of directors.

    "It's incredibly exciting to welcome Jigar to our board of directors. Not only does Jigar bring over 20 years of biotechnology industry experience, but he also comes with a unique position as an early employee of the company at its inception," said Richard Murray, Ph.D., chief executive officer and president of Jounce Therapeutics. "Jigar's leadership…

    CAMBRIDGE, Mass., Sept. 15, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced the appointment of former chief executive officer of Constellation Pharmaceuticals and former Jounce chief business officer, Jigar Raythatha, to its board of directors.

    "It's incredibly exciting to welcome Jigar to our board of directors. Not only does Jigar bring over 20 years of biotechnology industry experience, but he also comes with a unique position as an early employee of the company at its inception," said Richard Murray, Ph.D., chief executive officer and president of Jounce Therapeutics. "Jigar's leadership and business development expertise will enhance our board's diversified perspective. He was an integral part of creating the Jounce we know today, and we all look forward to collaborating with him once again."

    "Over the course of the last several years, Jounce has established a strong position as a leader in novel immuno-oncology drug discovery, and I am thrilled to join the board at this time in the company's life cycle. Jounce's recent growth, pipeline diversification and partnership strategy are core to its track record as a leader in transforming the immuno-oncology landscape," said Jigar Raythatha. "I look forward to providing insights from my prior experience with the company, coupled with my perspective as a former chief executive officer in the biotechnology industry."

    Jigar served as the chief executive officer of Constellation Pharmaceuticals, Inc. from 2017 until its acquisition by MorphoSys AG in July 2021. Jigar is also currently a member of the American Cancer Society New England Area Board. Before joining Constellation as chief executive officer, Jigar served as chief business officer of Jounce, where he helped build the company from inception to a 100-person, publicly traded organization. Earlier in his career, Jigar worked with Red Abbey Venture Partners and held roles of increasing responsibility at Biogen and as a management consultant at A.T. Kearney.

    In addition to Mr. Raythatha's appointment, Jounce announced that founding board member and previous interim chief executive officer, Cary Pfeffer, M.D., a partner at Third Rock Ventures, will resign from the Jounce board, effective December 31, 2021. Dr. Pfeffer was a founding member of Jounce's board of directors since 2013 and also served as chair of the Jounce board from 2014 to 2016.

    "On behalf of the Jounce Board of Directors, I want to thank Cary for his years of dedication to Jounce's science, team and mission," said Perry Karsen, chair of the Board of Jounce Therapeutics. "Cary's initial vision, his continuous guidance, and his unwavering support were invaluable to the creation and development of Jounce's Translational Science Platform, helping us further our goal of matching the right immunotherapy to the right patients for meaningful and long-lasting therapeutic benefit."

    About Jounce Therapeutics

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce's highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, of JTX-8064 as a monotherapy and in combination with pimivalimab (formerly JTX-4014), Jounce's internal PD-1 inhibitor, is currently enrolling patients with advanced solid tumors. Jounce's most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS and is currently being studied in the SELECT Phase 2 trial. Pimivalimab is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce's broader pipeline. Additionally, Jounce obtained IND clearance for and exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. For more information, please visit www.jouncetx.com.

    Cautionary Note Regarding Forward-Looking Statements

    Various statements in this release concerning Jounce's future expectations, plans and prospects, including without limitation, Jounce's expectations regarding the progress and results of clinical trials of Jounce's product candidates, including JTX-8064, vopratelimab and pimivalimab; and identification, selection and enrollment of patients for Jounce's clinical trials may constitute forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995 and other federal securities laws and are subject to substantial risks, uncertainties and assumptions. You should not place reliance on these forward-looking statements, which often include words such as "goal," "will" or similar terms, variations of such terms or the negative of those terms. Although Jounce believes that the expectations reflected in the forward-looking statements are reasonable, Jounce cannot guarantee such outcomes. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors, including, without limitation, risks that the COVID-19 pandemic may disrupt Jounce's business and/or the global healthcare system more severely than anticipated, which may have the effect of delaying enrollment and completion of Jounce's ongoing clinical trials, or delaying timelines or data disclosures and regulatory submissions for its product candidates; Jounce's ability to successfully demonstrate the efficacy and safety of its product candidates and future product candidates; the preclinical and clinical results for its product candidates, which may not support further development and marketing approval; the potential advantages of Jounce's product candidates; Jounce's ability to successfully manage its clinical trials; the development plans of its product candidates and any companion or complementary diagnostics; management of Jounce's supply chain for the delivery of drug product and materials for use in clinical trials and research and development activities; actions of regulatory agencies, which may affect the initiation, timing and progress of preclinical studies and clinical trials of Jounce's product candidates; Jounce's ability to obtain, maintain and protect its intellectual property; Jounce's ability to manage operating expenses and capital expenditures; and those risks more fully discussed in the section entitled "Risk Factors" in Jounce's most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission as well as discussions of potential risks, uncertainties, and other important factors in Jounce's subsequent filings with the Securities and Exchange Commission. All such statements speak only as of the date made, and Jounce undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise.

    Investor and Media Contacts:

    Mark Yore

    Jounce Therapeutics, Inc.

    +1-857-200-1255

    myore@jouncetx.com

    Julie Seidel

    Stern Investor Relations

    +1-212-362-1200

    Julie.Seidel@sternir.com



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  2. CAMBRIDGE, Mass., Sept. 02, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that company management will participate at several upcoming investor conferences in September:

    • 2021 Wells Fargo Virtual Healthcare Conference: Fireside chat on Friday September 10, 2021 at 8:00 a.m. ET.
    • H.C. Wainwright 23rd Annual Global Investment Conference: Presentation will be available on-demand during the conference, starting on Monday, September 13, 2021 at 7:00 a.m. ET.
    • Baird's 2021 Global Healthcare Conference: Presentation on Wednesday, September 15, 2021 at 12:15 p.m. ET. 
    • 2021 Cantor Fitzgerald Virtual

    CAMBRIDGE, Mass., Sept. 02, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that company management will participate at several upcoming investor conferences in September:

    • 2021 Wells Fargo Virtual Healthcare Conference: Fireside chat on Friday September 10, 2021 at 8:00 a.m. ET.
    • H.C. Wainwright 23rd Annual Global Investment Conference: Presentation will be available on-demand during the conference, starting on Monday, September 13, 2021 at 7:00 a.m. ET.
    • Baird's 2021 Global Healthcare Conference: Presentation on Wednesday, September 15, 2021 at 12:15 p.m. ET. 
    • 2021 Cantor Fitzgerald Virtual Global Healthcare Conference: Presentation on Wednesday, September 29, 2021 at 4:00 p.m. ET.

    A webcast of the presentations will be available by visiting "Events and Presentations" in the Investors and Media section of Jounce's website at www.jouncetx.com. A replay of the webcasts will be archived for 30 days following the presentation.

    About Jounce Therapeutics

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce's highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, of JTX-8064 as a monotherapy and in combination with pimivalimab (formerly JTX-4014), Jounce's internal PD-1 inhibitor, is currently enrolling patients with advanced solid tumors. Jounce's most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS and is currently being studied in the SELECT Phase 2 trial. Pimivalimab is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce's broader pipeline. Additionally, Jounce obtained IND clearance for and exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. For more information, please visit www.jouncetx.com.

    Investor and Media Contacts:

    Mark Yore

    Jounce Therapeutics, Inc.

    +1-857-200-1255

    myore@jouncetx.com

    Julie Seidel

    Stern Investor Relations

    +1-212-362-1200

    Julie.Seidel@sternir.com



    Primary Logo

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  3. - INNATE monotherapy dose escalation enrollment completed and target dose selected, on track to initiate indication specific expansions in third quarter 2021-

    - Announced two additional LILRB family targets as potential future development candidates -

    - Ended the quarter with $246.1 million in cash, cash equivalents and investments -

    - Company to host conference call and webcast today at 8:00 AM ET -

    CAMBRIDGE, Mass., Aug. 05, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today reported financial results for the second quarter ended June 30, 2021 and provided a corporate update.

    "I am very pleased…

    - INNATE monotherapy dose escalation enrollment completed and target dose selected, on track to initiate indication specific expansions in third quarter 2021-

    - Announced two additional LILRB family targets as potential future development candidates -

    - Ended the quarter with $246.1 million in cash, cash equivalents and investments -

    - Company to host conference call and webcast today at 8:00 AM ET -

    CAMBRIDGE, Mass., Aug. 05, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today reported financial results for the second quarter ended June 30, 2021 and provided a corporate update.

    "I am very pleased with the progress Jounce has made this quarter as we continued to advance our two proof of concept studies, INNATE and SELECT, achieved IND clearance on our fourth internally discovered program and expanded our discovery programs to include additional LILRB family members. Our team has made important and rapid progress in our INNATE study with the announcement today of monotherapy dose escalation enrollment completion and target dose selection. We look forward to beginning the next stages of the trial in third quarter of this year," said Richard Murray, Ph.D., chief executive officer and president of Jounce Therapeutics. "We remain steadfast in our commitment to discover and develop novel IO therapies to meet the growing unmet medical need experienced in cancer patients, particularly in the area of PD-(L)1 inhibitor resistance. We believe our focus on translational science, biomarker approaches, and targeting new immune mechanisms leads us closer to bringing the right immunotherapies to the right patients."

    Pipeline Update:

    JTX-8064 (LILRB2 / ILT4)

    • Completed enrollment in monotherapy dose escalation portion of INNATE: Jounce announces today that the monotherapy dose escalation portion of the Phase 1 trial of JTX-8064 is complete. The monotherapy dose escalation included seven doses ranging from 50 mg to the highest planned dose of 1200 mg. To date, JTX-8064 has been well-tolerated with no dose limiting toxicities.
    • Identified target dose for next stages of INNATE: Jounce announces today the selection of its target dose of 700 mg. The selected target dose was based on a combination of safety, pharmacokinetic, and receptor occupancy data in the first three-week cycle. During the third quarter of 2021, Jounce expects to open eight expansion cohorts for enrollment, one with JTX-8064 monotherapy at its target dose and seven with JTX-8064 in combination with pimivalimab.
    • Presented trial in progress posters at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting: In June 2021, Jounce presented a trial in progress poster at the ASCO Annual Meeting on INNATE. The poster included the study design and the rationale for indications chosen for the expansion cohorts.

    Vopratelimab (ICOS) and Pimivalimab (PD-1)

    • Continued enrollment in Phase 2 SELECT trial of vopratelimab: Enrollment continues in SELECT, a randomized Phase 2 trial to evaluate vopratelimab in combination with pimivalimab versus pimivalimab alone in immunotherapy naïve, TISvopra biomarker-selected, second line non-small cell lung cancer (NSCLC) patients. The SELECT trial also aims to provide additional important single agent data for pimivalimab in a new biomarker selection paradigm. Jounce is on track to report data from the SELECT trial in 2022.
    • Presented trial in progress poster at the ASCO 2021 Annual Meeting:   In June 2021, Jounce presented a trial in progress poster at the ASCO Annual Meeting on SELECT. The poster described the study design, TISvopra biomarker, and patient selection strategy of the SELECT trial.

    JTX-1811 (CCR8)

    • Clearance of IND triggering first milestone under Gilead license agreement: In June 2021, Jounce received clearance from the U.S. Food and Drug Administration (FDA) of an investigational new drug (IND) application for JTX-1811, a potential first-in-class antibody designed to bind to CCR8 and selectively deplete immunosuppressive tumor-infiltrating T regulatory cells. The IND clearance triggered a $25.0 million milestone payment to Jounce which was received in July 2021. Gilead now has sole rights to develop and commercialize the JTX-1811 program, which will be referred to as GS-1811 in their pipeline.

    Discovery Pipeline

    • Announced new discovery program targets: Jounce continues to invest in and advance its growing immuno-oncology pipeline. The broad discovery pipeline includes multiple programs targeting diverse immune cell types and PD-(L)1 inhibitor resistance mechanisms. Jounce is rapidly advancing two additional LILRB family programs through discovery, one targeting LILRB1 and the other targeting LILRB4. With the goal of submitting a new IND every 12 to 18 months, Jounce expects at least one of its next development candidates to target the LILRB family of receptors.

    Second Quarter 2021 Financial Results:

    • Cash position: As of June 30, 2021, cash, cash equivalents and investments were $246.1 million, compared to $213.2 million as of December 31, 2020. The increase was primarily due to receipt of $90.9 million in net proceeds from the follow-on public offering and sales under Jounce's at-the-market offering program completed during the period, offset by operating expenses incurred. This amount excludes the $25.0 million milestone Jounce received from Gilead in July 2021.
    • License and collaboration revenue: Jounce recognized $25.4 million of license and collaboration revenue during the second quarter of 2021. License and collaboration revenue recognized during the period was related to milestone achievement and research and transition services performed under the license agreement with Gilead. No revenue was recognized for the same period in 2020.
    • Research and development expenses: Research and development expenses were $22.1 million for the second quarter of 2021, compared to $21.0 million for the same period in 2020. The increase in research and development expenses was primarily due to increased manufacturing activities performed for Jounce's development programs and increased clinical and regulatory spend on JTX-8064 offset by decreased spend on vopratelimab.
    • General and administrative expenses: General and administrative expenses were $7.3 million for the second quarter of 2021, compared to $7.2 million for the same period in 2020. The increase in general and administrative expenses was primarily due to increased insurance expense.
    • Net loss: Net loss was $4.0 million for the second quarter of 2021, resulting in basic and diluted net loss per share of $0.08. Net loss was $28.0 million for the same period in 2020, resulting in a basic and diluted net loss per share of $0.82. The decrease in net loss and net loss per share was attributable to revenue recognized in the second quarter of 2021.

    Financial Guidance:

    Based on its current operating and development plans, Jounce continues to expect gross cash burn on operating expenses and capital expenditures for the full year 2021 to be approximately $95.0 million to $110.0 million.

    Given the strength of its balance sheet, Jounce expects its existing cash, cash equivalents and investments to be sufficient to enable the funding of its operating expenses and capital expenditure requirements through the third quarter of 2023.

    Conference Call and Webcast Information:

    Jounce Therapeutics will host a live conference call and webcast today at 8:00 a.m. ET. To access the conference call, please dial (866) 916-3380 (domestic) or (210) 874-7772 (international) and refer to conference ID 4291658. The live webcast can be accessed under "Events & Presentations" in the Investors and Media section of Jounce's website at www.jouncetx.com. The webcast will be archived and made available for replay on Jounce's website approximately two hours after the call and will be available for 30 days.

    About Jounce Therapeutics:

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce's highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, of JTX-8064 as a monotherapy and in combination with pimivalimab (formerly JTX-4014), Jounce's internal PD-1 inhibitor, is currently enrolling patients with advanced solid tumors. Jounce's most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS and is currently being studied in the SELECT Phase 2 trial. Pimivalimab is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce's broader pipeline. Additionally, Jounce obtained IND clearance for and exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. For more information, please visit www.jouncetx.com.

    Cautionary Note Regarding Forward-Looking Statements:

    Various statements in this release concerning Jounce's future expectations, plans and prospects, including without limitation, Jounce's expectations regarding financial guidance, operating expenses and capital expenditures; the timing, initiation, progress, results of and release of data for clinical trials of Jounce's product candidates, including JTX-8064, vopratelimab and pimivalimab; identification, selection and enrollment of patients for Jounce's clinical trials; the timing of IND filings; and the timing, progress and results of preclinical studies for Jounce's product candidates, including JTX-1811, and any future product candidates may constitute forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995 and other federal securities laws and are subject to substantial risks, uncertainties and assumptions. You should not place reliance on these forward-looking statements, which often include words such as "aim," "goal," "expect," "plan," "on track," "will" or similar terms, variations of such terms or the negative of those terms. Although Jounce believes that the expectations reflected in the forward-looking statements are reasonable, Jounce cannot guarantee such outcomes. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors, including, without limitation, risks that the COVID-19 pandemic may disrupt Jounce's business and/or the global healthcare system more severely than anticipated, which may have the effect of delaying enrollment and completion of Jounce's ongoing clinical trials, or delaying timelines or data disclosures and regulatory submissions for its product candidates; Jounce's ability to successfully demonstrate the efficacy and safety of its product candidates and future product candidates; the preclinical and clinical results for its product candidates, which may not support further development and marketing approval; the potential advantages of Jounce's product candidates; Jounce's ability to successfully manage its clinical trials; the development plans of its product candidates and any companion or complementary diagnostics; management of Jounce's supply chain for the delivery of drug product and materials for use in clinical trials and research and development activities; actions of regulatory agencies, which may affect the initiation, timing and progress of preclinical studies and clinical trials of Jounce's product candidates; Jounce's ability to obtain, maintain and protect its intellectual property; Jounce's ability to manage operating expenses and capital expenditures; and those risks more fully discussed in the section entitled "Risk Factors" in Jounce's most recent Annual Report on Form 10-K filed with the Securities and Exchange Commission as well as discussions of potential risks, uncertainties, and other important factors in Jounce's subsequent filings with the Securities and Exchange Commission. All such statements speak only as of the date made, and Jounce undertakes no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise.

     Three Months Ended

    June 30,
     Six Months Ended

    June 30,
     2021 2020 2021 2020
    Revenue:       
    License and collaboration revenue—related party$25,368  $  $26,907  $ 
    Operating expenses:       
    Research and development22,100  21,023  42,607  40,669 
    General and administrative7,317  7,226  14,932  14,765 
    Total operating expenses29,417  28,249  57,539  55,434 
    Operating loss(4,049) (28,249) (30,632) (55,434)
    Other income, net40  285  89  1,035 
    Loss before provision for income taxes(4,009) (27,964) (30,543) (54,399)
    Provision for income taxes2  4  3  12 
    Net loss$(4,011) $(27,968) $(30,546) $(54,411)
    Net loss per share, basic and diluted

    $(0.08) $(0.82) $(0.63) $(1.60)
    Weighted-average common shares outstanding, basic and diluted51,212  34,053  48,601  34,041 
     
     
     
    Jounce Therapeutics, Inc.

    Selected Condensed Consolidated Balance Sheet Data (unaudited)

    (amounts in thousands)
        
     June 30, December 31,
     2021 2020
    Cash, cash equivalents and investments$246,148  $213,188 
    Working capital$241,278  $192,067 
    Total assets$306,160  $244,236 
    Total stockholders' equity$278,462  $211,294 

    Investor and Media Contact:

    Mark Yore

    Jounce Therapeutics, Inc.

    +1-857-200-1255

    myore@jouncetx.com

    Julie Seidel

    Stern Investor Relations

    +1-212-362-1200

    Julie.Seidel@sternir.com



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    View Full Article Hide Full Article
  4. CAMBRIDGE, Mass., July 29, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that it will report second quarter 2021 financial results and provide a corporate update before market open on Thursday, August 5, 2021. Jounce Therapeutics' management team will host a live conference call and webcast at 8:00am ET.

    Conference Call and Webcast
    To access the conference call, please dial (866) 916-3380 (domestic) or (210) 874-7772 (international) and refer to conference ID 4291658. The live webcast can be accessed under "Events & Presentations" in the Investors and Media section of Jounce's website…

    CAMBRIDGE, Mass., July 29, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that it will report second quarter 2021 financial results and provide a corporate update before market open on Thursday, August 5, 2021. Jounce Therapeutics' management team will host a live conference call and webcast at 8:00am ET.

    Conference Call and Webcast

    To access the conference call, please dial (866) 916-3380 (domestic) or (210) 874-7772 (international) and refer to conference ID 4291658. The live webcast can be accessed under "Events & Presentations" in the Investors and Media section of Jounce's website at www.jouncetx.com. The webcast will be archived and made available for replay on the company's website approximately two hours after the call and will be available for 30 days thereafter.

    About Jounce Therapeutics

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce's highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, of JTX-8064 as a monotherapy and in combination with pimivalimab (formerly JTX-4014), Jounce's internal PD-1 inhibitor, is currently enrolling patients with advanced solid tumors. Jounce's most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS, and is currently being studied in the SELECT Phase 2 trial. Pimivalimab is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce's broader pipeline. Additionally, Jounce obtained IND clearance for and exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. For more information, please visit www.jouncetx.com.

    Investor and Media Contacts:

    Mark Yore

    Jounce Therapeutics, Inc.

    +1-857-200-1255

    myore@jouncetx.com

    Julie Seidel

    Stern Investor Relations

    +1-212-362-1200

    Julie.Seidel@sternir.com



    Primary Logo

    View Full Article Hide Full Article
  5. CAMBRIDGE, Mass., July 07, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that Dmitri Wiederschain, Ph.D., Chief Scientific Officer will participate in a panel discussion at the William Blair's Biotech Focus Conference taking place virtually on Wednesday, July 14, 2021 at 4:20 PM ET.

    A webcast of the panel will be available by visiting "Events and Presentations" in the Investors and Media section of Jounce's website at www.jouncetx.com. A replay of the webcast will be archived for 30 days following the presentation.

    About Jounce Therapeutics
    Jounce Therapeutics, Inc. is a clinical-stage…

    CAMBRIDGE, Mass., July 07, 2021 (GLOBE NEWSWIRE) -- Jounce Therapeutics, Inc. (NASDAQ:JNCE), a clinical-stage company focused on the discovery and development of novel cancer immunotherapies and predictive biomarkers, today announced that Dmitri Wiederschain, Ph.D., Chief Scientific Officer will participate in a panel discussion at the William Blair's Biotech Focus Conference taking place virtually on Wednesday, July 14, 2021 at 4:20 PM ET.

    A webcast of the panel will be available by visiting "Events and Presentations" in the Investors and Media section of Jounce's website at www.jouncetx.com. A replay of the webcast will be archived for 30 days following the presentation.

    About Jounce Therapeutics

    Jounce Therapeutics, Inc. is a clinical-stage immunotherapy company dedicated to transforming the treatment of cancer by developing therapies that enable the immune system to attack tumors and provide long-lasting benefits to patients through a biomarker-driven approach. Jounce currently has multiple development stage programs ongoing while simultaneously advancing additional early-stage assets from its robust discovery engine based on its Translational Science Platform. Jounce's highest priority program, JTX-8064, is a LILRB2 (ILT4) receptor antagonist shown to reprogram immune-suppressive tumor associated macrophages to an anti-tumor state in preclinical studies. A Phase 1 clinical trial, named INNATE, of JTX-8064 as a monotherapy and in combination with pimivalimab (formerly JTX-4014), Jounce's internal PD-1 inhibitor, is currently enrolling patients with advanced solid tumors. Jounce's most advanced product candidate, vopratelimab, is a monoclonal antibody that binds to and activates ICOS, and is currently being studied in the SELECT Phase 2 trial. Pimivalimab is a PD-1 inhibitor intended for combination use in the INNATE and SELECT trials and with Jounce's broader pipeline. Additionally, Jounce obtained IND clearance for and exclusively licensed worldwide rights to JTX-1811, a monoclonal antibody targeting CCR8 and designed to selectively deplete T regulatory cells in the tumor microenvironment, to Gilead Sciences, Inc. For more information, please visit www.jouncetx.com.

    Investor and Media Contacts:

    Mark Yore

    Jounce Therapeutics, Inc.

    +1-857-200-1255

    myore@jouncetx.com

    Julie Seidel

    Stern Investor Relations

    +1-212-362-1200

    Julie.Seidel@sternir.com



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