JANX Janux Therapeutics Inc.

32.43
+1.16  (+4%)
Previous Close 31.27
Open 31.5
52 Week Low 16.32
52 Week High 37.99
Market Cap $1,349,461,269
Shares 41,611,510
Float 23,433,838
Enterprise Value $1,304,533,917
Volume 96,685
Av. Daily Volume 0
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Latest News

  1. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer. Dr. Salek-Ardakani will lead the scientific advancement of Janux's proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to expand Janux's pipeline of next-generation T cell engager immunotherapies. Dr. Salek-Ardakani joins Janux from Pfizer, Inc., where he was responsible for formulating first-in-class discovery programs and platform initiatives to implement Pfizer's T-cell-targeted therapeutics strategy. Dr. Salek-Ardakani brings more than 20 years of experience as a scientific leader and drug developer in…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer. Dr. Salek-Ardakani will lead the scientific advancement of Janux's proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to expand Janux's pipeline of next-generation T cell engager immunotherapies. Dr. Salek-Ardakani joins Janux from Pfizer, Inc., where he was responsible for formulating first-in-class discovery programs and platform initiatives to implement Pfizer's T-cell-targeted therapeutics strategy. Dr. Salek-Ardakani brings more than 20 years of experience as a scientific leader and drug developer in multiple disease areas.

    "Shahram has deep scientific and leadership experience in drug development for immuno-oncology, with a special focus on T-cell-targeted therapies," said David Campbell, Ph.D., President and CEO of Janux. "We are pleased to welcome Shahram to the Janux team as we work to develop unique immunotherapies that have the potential to generate tumor-specific immune responses and activate a patient's immune system to recognize, attack, and eradicate the tumor."

    "Janux has developed a unique platform for next-generation T cell engager immunotherapies that is designed to maximize tumor cell killing while minimizing toxicity to healthy tissues," said Dr. Salek-Ardakani. "I look forward to advancing Janux's TRACTr platform technology and expanding Janux's pipeline of next-generation T cell engager immunotherapies that have the potential to improve the treatment of cancer."

    Prior to joining Janux, Dr. Salek-Ardakani was the Senior Director of Cancer Immunology at Pfizer. Previous to that, he was an associate professor at the University of Florida College of Medicine. Before that, Dr. Salek-Ardakani was a postdoctoral fellow and principal investigator at the La Jolla Institute for Immunology in San Diego. During that time, he received several institutional investigator awards from the National Institute of Health (NIH) for his work on T cell memory, mucosal vaccines, and immune regulation by members of the immunoglobulin and tumor necrosis factor receptor family. Dr. Salek-Ardakani has co-authored more than 70 publications in peer-reviewed journals. He has also served on several grant review study sections and special emphasis panels for the NIH. Dr. Salek-Ardakani holds a Ph.D. in oncology and M.Sc. in immunology and immunogenetics from the Cancer Research UK Manchester Institute.

    About Janux Therapeutics

    Janux Therapeutics is an innovative biopharmaceutical company developing next-generation therapeutics based on its proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to better treat patients suffering from cancer. Janux's initial focus is on developing a novel class of T cell engagers (TCEs), and its lead product candidates are designed to target clinically validated drug targets. While TCE therapeutics have displayed potent anti-tumor activity in hematological cancers, developing TCEs to treat solid tumors have faced challenges due to the limitations of prior TCE technologies, namely (i) overactivation of the immune system leading to cytokine release syndrome, (ii) on-target, healthy tissue toxicities, and (iii) poor pharmacokinetics leading to short half-life. Janux is using its TRACTr platform technology to engineer product candidates designed to overcome these limitations. Janux is developing a broad pipeline with lead programs targeting prostate-specific membrane antigen (PSMA), epidermal growth factor receptor (EGFR), and trophoblast cell surface antigen 2 (TROP2), with all of its programs currently in the IND-enabling or discovery stage. For more info, www.januxrx.com.

    Forward-Looking Statements

    This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, Janux's ability to bring new treatments to cancer patients in need and the progress and expected timing of Kura's drug development programs. Factors that may cause actual results to differ materially include the risk that compounds that appear promising in early research do not demonstrate safety and/or efficacy in later preclinical studies or clinical trials, the risk that Janux may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings and applications, risks associated with reliance on third parties to successfully conduct clinical trials, the risks associated with reliance on outside financing to meet capital requirements, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "promise," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Janux faces, please refer to Janux's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Janux assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

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  2. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000 shares of its common stock, which includes 1,710,000 shares sold pursuant to the exercise in full by the underwriters of their option to purchase additional shares, at a price to the public of $17.00 per share. Including the option exercise, the aggregate gross proceeds to Janux from the offering were approximately $222.9 million, before deducting the underwriting discounts and commissions and offering expenses. The shares began trading on the Nasdaq Global Market on June 11, 2021, under the ticker symbol "JANX."

    BofA Securities…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000 shares of its common stock, which includes 1,710,000 shares sold pursuant to the exercise in full by the underwriters of their option to purchase additional shares, at a price to the public of $17.00 per share. Including the option exercise, the aggregate gross proceeds to Janux from the offering were approximately $222.9 million, before deducting the underwriting discounts and commissions and offering expenses. The shares began trading on the Nasdaq Global Market on June 11, 2021, under the ticker symbol "JANX."

    BofA Securities, Cowen and Evercore ISI acted as joint book-running managers for the offering. H.C. Wainwright & Co. acted as lead manager for the offering.

    Registration statements relating to the offering of these securities have been filed with the Securities and Exchange Commission (SEC) and became effective on June 10, 2021. Copies of the registration statements can be accessed through the SEC's website at www.sec.gov. This offering was made only by means of a written prospectus. Copies of the final prospectus relating to the initial public offering may be obtained from: BofA Securities, Attention: Prospectus Department, NC1-004-03-43, 200 North College Street, 3rd Floor, Charlotte, NC 28255-0001 or by email at ; Cowen and Company, LLC, c/o Broadridge Financial Solutions, Attention: Prospectus Department, 1155 Long Island Avenue, Edgewood, NY 11717, or by telephone at (833) 297-2926 or by email at ; or Evercore Group L.L.C., Attention: Equity Capital Markets, 55 East 52nd Street, 36th Floor, New York, NY 10055, or by telephone at (888) 474-0200 or by email at .

    This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

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