JANX Janux Therapeutics Inc.

22.76
-2.26  -9%
Previous Close 25.02
Open 24.49
52 Week Low 16.32
52 Week High 37.99
Market Cap $947,077,968
Shares 41,611,510
Float 23,433,838
Enterprise Value $1,044,461,980
Volume 76,533
Av. Daily Volume 175,499
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Latest News

  1. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms, today announced the additions of Ronald W. Barrett, Ph.D., and Alana McNulty as members of the Company's Board of Directors. Dr. Barrett is a scientist entrepreneur with more than 30 years of experience in the biopharmaceutical industry, founding and leading biopharmaceutical companies, including advancing research that has led to FDA approval of three drugs. Ms. McNulty has more than 30 years of experience in finance and business development for private and publicly traded…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms, today announced the additions of Ronald W. Barrett, Ph.D., and Alana McNulty as members of the Company's Board of Directors. Dr. Barrett is a scientist entrepreneur with more than 30 years of experience in the biopharmaceutical industry, founding and leading biopharmaceutical companies, including advancing research that has led to FDA approval of three drugs. Ms. McNulty has more than 30 years of experience in finance and business development for private and publicly traded biopharmaceutical companies.

    "Ron has deep expertise in building and operating biotech companies and successfully bringing a portfolio of preclinical drug candidates into clinical studies, including advancing a drug through FDA approval, and Alana has exceptional experience in finance and business development for a wide range of biopharmaceutical companies," said David Campbell, Ph.D., President and CEO of Janux Therapeutics. "The Board and I welcome their complementary expertise as we continue to build the Company and look to advance our programs into the clinic."

    Dr. Barrett is CEO and Chairman of Medikine, Inc., a preclinical-stage biopharmaceutical company utilizing a proprietary platform to identify peptide mimetics of clinically relevant cytokines that interact with the broad class of heterodimeric cytokine receptors. Prior to Medikine he cofounded XenoPort, Inc., where he was the CEO and a Director for more than 15 years. Shortly after his tenure, XenoPort was acquired by Arbor Pharmaceuticals, LLC. Under his guidance, XenoPort completed multiple private and public financings, corporate partnerships, and advanced five in-house discovered compounds into human trials including mid- to late-stage clinical trials. He led the company's efforts that resulted in the FDA approval of HORIZANT® (gabapentin enacarbil), the first and only non-dopaminergic drug approved for moderate to severe restless legs syndrome in the U.S. Prior to founding XenoPort, Dr. Barrett was Senior Vice President of Research at Affymax Research Institute, where he pioneered the development and use of new drug discovery technology – work that led to two FDA-approved medicines. He is currently a Director of Concert Pharmaceuticals, Inc. and Quadriga Bioscience, Inc. Dr. Barrett co-authored more than 50 manuscripts in peer-reviewed journals and is an inventor on more than 50 issued patents in the U.S. He received a B.S. degree in biology from Bucknell University and a Ph.D. degree in pharmacology from Rutgers University.

    Over her career, Ms. McNulty has led or played a key role in transactions with an aggregate value greater than $2 billion, including private and public financings, mergers and acquisitions, corporate partnerships, and debt financings. She is currently Chief Business Officer of eFFECTOR Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on pioneering the development of a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). She also served as Chief Financial Officer for eFFECTOR for more than eight years. Prior to eFFECTOR, Ms. McNulty served as Chief Financial Officer of a number of biopharmaceutical companies, including Lumena Pharmaceuticals, Inc. (acquired by Shire plc), Excaliard Pharmaceuticals, Inc. (acquired by Pfizer Inc.), BrainCells Inc., and Elitra Pharmaceuticals, Inc. Prior to that, Ms. McNulty was Head of Corporate Development and a General Manager of a business unit at Advanced Tissue Sciences, Inc. Ms. McNulty received a B.A. in biology with high honors from UC Santa Barbara, where she graduated Phi Beta Kappa, and an MBA from the Anderson School of Business at UCLA.

    About Janux Therapeutics

    Janux Therapeutics is an innovative biopharmaceutical company developing next-generation therapeutics based on applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms to better treat patients suffering from cancer. Janux's initial focus is on developing a novel class of T cell engagers (TCEs), and its lead product candidates are designed to target clinically validated drug targets. While TCE therapeutics have displayed potent anti-tumor activity in hematological cancers, developing TCEs to treat solid tumors have faced challenges due to the limitations of prior TCE technologies, namely (i) overactivation of the immune system leading to cytokine release syndrome, (ii) on-target, healthy tissue toxicities, and (iii) poor pharmacokinetics leading to short half-life. Janux is using its TRACTr platform technology to engineer product candidates designed to overcome these limitations. Janux is developing a broad pipeline with lead TRACTr programs targeting prostate-specific membrane antigen (PSMA), epidermal growth factor receptor (EGFR), and trophoblast cell surface antigen 2 (TROP2), and its lead TRACIr program targeting PD-L1xCD28, with all of its programs currently in the IND-enabling or discovery stage. For more information, please visit www.januxrx.com.

    Forward-Looking Statements

    This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, Janux's ability to bring new treatments to cancer patients in need, and the progress and expected timing of Janux's drug development programs. Factors that may cause actual results to differ materially include the risk that compounds that appear promising in early research do not demonstrate safety and/or efficacy in later preclinical studies or clinical trials, the risk that Janux may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings and applications, risks associated with reliance on third parties to successfully conduct clinical trials, the risks associated with reliance on outside financing to meet capital requirements, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "promise," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Janux faces, please refer to Janux's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Janux assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

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  2. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms, today announced that Janux management will present at the virtual H.C. Wainwright 23rd Annual Global Investor Conference being held September 13 to 15, 2021.

    The corporate presentation will be available for on-demand viewing beginning September 13, 2021, at 7:00 a.m. ET via the Investors & Media section of Janux's website. An archived replay of the webcast will be available on the website for approximately 90 days following the presentation.

    About Janux Therapeutics

    Janux…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms, today announced that Janux management will present at the virtual H.C. Wainwright 23rd Annual Global Investor Conference being held September 13 to 15, 2021.

    The corporate presentation will be available for on-demand viewing beginning September 13, 2021, at 7:00 a.m. ET via the Investors & Media section of Janux's website. An archived replay of the webcast will be available on the website for approximately 90 days following the presentation.

    About Janux Therapeutics

    Janux Therapeutics is an innovative biopharmaceutical company developing next-generation therapeutics based on applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms to better treat patients suffering from cancer. Janux's initial focus is on developing a novel class of T cell engagers (TCEs), and its lead product candidates are designed to target clinically validated drug targets. While TCE therapeutics have displayed potent anti-tumor activity in hematological cancers, developing TCEs to treat solid tumors have faced challenges due to the limitations of prior TCE technologies, namely (i) overactivation of the immune system leading to cytokine release syndrome, (ii) on-target, healthy tissue toxicities, and (iii) poor pharmacokinetics leading to short half-life. Janux is using its TRACTr platform technology to engineer product candidates designed to overcome these limitations. Janux is developing a broad pipeline with lead TRACTr programs targeting prostate-specific membrane antigen (PSMA), epidermal growth factor receptor (EGFR), and trophoblast cell surface antigen 2 (TROP2), and its lead TRACIr program targeting PD-L1xCD28, with all of its programs currently in the IND-enabling or discovery stage. For more information, please visit www.januxrx.com.

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  3. -Successful $222.9 million IPO in June brings total funds raised in the quarter to $347.9 million-

    -Company on-track to submit IND filings for multiple programs in 2022-

    -Management team strengthened with key appointments-

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies based on its TRACTr platform technology, today reported financial results for the quarter ended June 30, 2021.

    "With the successful completions of a Series B financing and IPO this past quarter, we are well-capitalized to advance our novel TRACTr platform technology and next-generation T cell engager immunotherapies, with the potential to improve the treatment of cancer," said David Campbell, Ph.D…

    -Successful $222.9 million IPO in June brings total funds raised in the quarter to $347.9 million-

    -Company on-track to submit IND filings for multiple programs in 2022-

    -Management team strengthened with key appointments-

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies based on its TRACTr platform technology, today reported financial results for the quarter ended June 30, 2021.

    "With the successful completions of a Series B financing and IPO this past quarter, we are well-capitalized to advance our novel TRACTr platform technology and next-generation T cell engager immunotherapies, with the potential to improve the treatment of cancer," said David Campbell, Ph.D., President and CEO of Janux. "Janux has also significantly strengthened the organization with key hires to our senior management team. These team members bring invaluable expertise and decades of drug development experience, specifically in T cell therapeutics, to propel our broad preclinical pipeline toward the clinic."

    Recent Business Highlights:

    • TRACTr product candidates advancing as planned. Janux's lead TRACTr programs of next-generation T cell engagers for PSMA, EGFR, TROP2, and its costimulatory bispecific TRACIr program remain on track as they move through preclinical development. Janux continues to expect to submit at least two Investigational New Drug (IND) applications by the end of 2022.
    • Strengthened management team with appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer, and Wayne Godfrey, M.D., as Chief Medical Officer. Dr. Salek-Ardakani brings more than 20 years of experience as a scientific leader and drug developer in multiple disease areas, most recently serving as the Senior Director of Cancer Immunology at Pfizer, Inc., where he was responsible for formulating first-in-class discovery programs and platform initiatives to implement Pfizer's T cell targeted therapeutics strategy. Dr. Godfrey brings more than 25 years of drug development, clinical strategy, and research experience in cancer immunology and immunotherapy at leading pharmaceutical and biotechnology companies, most recently serving as the Vice President of Clinical Development at IGM Biosciences, Inc., where he led the global clinical development of IGM's emerging pipeline of proprietary bispecific T cell engaging IgM antibodies.
    • Completed Series B financing and initial public offering (IPO). In April 2021, Janux completed a Series B financing, raising gross proceeds of $125.0 million. In June 2021, Janux completed an initial public offering, selling 13,110,000 shares of its common stock at a price to the public of $17.00 per share, for aggregate gross proceeds of $222.9 million (before deducting underwriting discounts and commissions and offering costs).

    Second Quarter 2021 Financial Highlights:

    • Cash and cash equivalents and short-term investments: As of June 30, 2021, Janux reported cash and cash equivalents and short-term investments of $394.2 million, compared to $7.8 million at December 31, 2020.
    • Research and development expenses: Research and development expenses for the quarter ended June 30, 2021 were $4.7 million, compared to $0.7 million for the comparable period in 2020. The increase in research and development expenses in 2021 was primarily attributable to the development of the TRACTr platform technology and programs. Janux also incurred additional personnel-related expenses, including stock-based compensation, as operations grew in support of program advances.
    • General and administrative expenses: General and administrative expenses for the quarter ended June 30, 2021 were $2.0 million, compared to $0.4 million for the same period in 2020. The increase in general and administrative expenses was primarily attributable to an increase in personnel-related expenses including stock-based compensation, due to increased headcount in 2021. The increase in general and administrative expenses were also due to an increase in legal fees, professional fees, and other various general and administrative expenses, as Janux now operates as a public company.
    • Net loss: For the quarter ended June 30, 2021, Janux reported a net loss of $6.2 million, compared to a net loss of $2.5 million for the comparable period in 2020.

    About Janux Therapeutics

    Janux Therapeutics is an innovative biopharmaceutical company developing next-generation therapeutics based on its proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to better treat patients suffering from cancer. Janux's initial focus is on developing a novel class of T cell engagers (TCEs), and its lead product candidates are designed to target clinically validated drug targets. While TCE therapeutics have displayed potent anti-tumor activity in hematological cancers, developing TCEs to treat solid tumors have faced challenges due to the limitations of prior TCE technologies, namely (i) overactivation of the immune system leading to cytokine release syndrome, (ii) on-target, healthy tissue toxicities, and (iii) poor pharmacokinetics leading to short half-life. Janux is using its TRACTr platform technology to engineer product candidates designed to overcome these limitations. Janux is developing a broad pipeline with lead TRACTr programs targeting prostate-specific membrane antigen (PSMA), epidermal growth factor receptor (EGFR), and trophoblast cell surface antigen 2 (TROP2), and its lead TRACIr program targeting PD-L1xCD28, with all of its programs currently in the IND-enabling or discovery stage. For more info, www.januxrx.com.

    Forward-Looking Statements

    This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, Janux's ability to bring new treatments to cancer patients in need, the progress and expected timing of Janux's drug development programs, and the strength of Janux's balance sheet and the adequacy of cash on hand. Factors that may cause actual results to differ materially include the risk that compounds that appear promising in early research do not demonstrate safety and/or efficacy in later preclinical studies or clinical trials, the risk that Janux may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings and applications, risks associated with reliance on third parties to successfully conduct clinical trials, the risks associated with reliance on outside financing to meet capital requirements, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "promise," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Janux faces, please refer to Janux's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Janux assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

    Janux Therapeutics, Inc.

    Condensed Balance Sheets

    (in thousands)

     

     

     

    June 30,

    2021

     

     

    December 31,

    2020

     

    Assets

     

    (unaudited)

     

     

     

     

    Current assets:

     

     

     

     

     

     

    Cash and cash equivalents

     

    $

    251,625

     

     

    $

    7,813

     

    Short-term investments

     

     

    142,570

     

     

     

     

    Accounts receivable

     

     

    375

     

     

     

    8,000

     

    Prepaid expenses and other current assets

     

     

    2,038

     

     

     

    249

     

    Total current assets

     

     

    396,608

     

     

     

    16,062

     

    Property and equipment, net

     

     

    215

     

     

     

    155

     

    Total assets

     

    $

    396,823

     

     

    $

    16,217

     

     

     

     

     

     

     

     

    Liabilities, Convertible Preferred Stock and Stockholders' Equity (Deficit)

     

     

     

     

     

     

    Current liabilities:

     

     

     

     

     

     

    Accounts payable

     

    $

    354

     

     

    $

    428

     

    Accrued liabilities

     

     

    2,286

     

     

     

    751

     

    Current portion of deferred revenue

     

     

    5,065

     

     

     

    1,950

     

    Unvested stock liability

     

     

    1,500

     

     

     

    52

     

    Total current liabilities

     

     

    9,205

     

     

     

    3,181

     

    Deferred revenue, net of current portion

     

     

    2,823

     

     

     

    6,050

     

    Total liabilities

     

     

    12,028

     

     

     

    9,231

     

    Convertible preferred stock

     

     

     

     

     

    21,624

     

    Total stockholders' equity (deficit)

     

     

    384,795

     

     

     

    (14,638

    )

    Total liabilities, convertible preferred stock and stockholders' equity (deficit)

     

    $

    396,823

     

     

    $

    16,217

     

    Janux Therapeutics, Inc.

    Unaudited Condensed Statements of Operations and Comprehensive Loss

    (in thousands, except share and per share data)

     

     

     

    Three Months Ended

    June 30,

     

    Six Months Ended

    June 30,

     

     

    2021

     

    2020

     

    2021

     

    2020

    Collaboration revenue

     

    $

    482

     

     

    $

     

     

    $

    862

     

     

    $

     

    Operating expenses:

     

     

     

     

     

     

     

     

     

     

     

     

    Research and development

     

     

    4,737

     

     

     

    673

     

     

     

    6,662

     

     

     

    1,222

     

    General and administrative

     

     

    1,997

     

     

     

    433

     

     

     

    2,736

     

     

     

    710

     

    Total operating expenses

     

     

    6,734

     

     

     

    1,106

     

     

     

    9,398

     

     

     

    1,932

     

    Loss from operations

     

     

    (6,252

    )

     

     

    (1,106

    )

     

     

    (8,536

    )

     

     

    (1,932

    )

    Total other income (expense)

     

     

    46

     

     

     

    (1,354

    )

     

     

    46

     

     

     

    (1,941

    )

    Net loss

     

    $

    (6,206

    )

     

    $

    (2,460

    )

     

    $

    (8,490

    )

     

    $

    (3,873

    )

    Other comprehensive loss:

     

     

     

     

     

     

     

     

     

     

     

     

    Unrealized gain (loss) on available-for-sale securities, net

     

     

    (17

    )

     

     

     

     

     

    (17

    )

     

     

     

    Comprehensive loss

     

    $

    (6,223

    )

     

    $

    (2,460

    )

     

    $

    (8,507

    )

     

    $

    (3,873

    )

    Net loss per common share, basic and diluted

     

    $

    (0.62

    )

     

    $

    (2.76

    )

     

    $

    (1.52

    )

     

    $

    (4.52

    )

    Weighted-average shares of common stock outstanding, basic and diluted

     

     

    10,033,328

     

     

     

    890,916

     

     

     

    5,596,900

     

     

     

    856,093

     

     

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  4. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer.

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer. Dr. Salek-Ardakani will lead the scientific advancement of Janux's proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to expand Janux's pipeline of next-generation T cell engager immunotherapies. Dr. Salek-Ardakani joins Janux from Pfizer, Inc., where he was responsible for formulating…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer.

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the appointment of Shahram Salek-Ardakani, Ph.D., as Chief Scientific Officer. Dr. Salek-Ardakani will lead the scientific advancement of Janux's proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to expand Janux's pipeline of next-generation T cell engager immunotherapies. Dr. Salek-Ardakani joins Janux from Pfizer, Inc., where he was responsible for formulating first-in-class discovery programs and platform initiatives to implement Pfizer's T-cell-targeted therapeutics strategy. Dr. Salek-Ardakani brings more than 20 years of experience as a scientific leader and drug developer in multiple disease areas.

    "Shahram has deep scientific and leadership experience in drug development for immuno-oncology, with a special focus on T-cell-targeted therapies," said David Campbell, Ph.D., President and CEO of Janux. "We are pleased to welcome Shahram to the Janux team as we work to develop unique immunotherapies that have the potential to generate tumor-specific immune responses and activate a patient's immune system to recognize, attack, and eradicate the tumor."

    "Janux has developed a unique platform for next-generation T cell engager immunotherapies that is designed to maximize tumor cell killing while minimizing toxicity to healthy tissues," said Dr. Salek-Ardakani. "I look forward to advancing Janux's TRACTr platform technology and expanding Janux's pipeline of next-generation T cell engager immunotherapies that have the potential to improve the treatment of cancer."

    Prior to joining Janux, Dr. Salek-Ardakani was the Senior Director of Cancer Immunology at Pfizer. Previous to that, he was an associate professor at the University of Florida College of Medicine. Before that, Dr. Salek-Ardakani was a postdoctoral fellow and principal investigator at the La Jolla Institute for Immunology in San Diego. During that time, he received several institutional investigator awards from the National Institute of Health (NIH) for his work on T cell memory, mucosal vaccines, and immune regulation by members of the immunoglobulin and tumor necrosis factor receptor family. Dr. Salek-Ardakani has co-authored more than 70 publications in peer-reviewed journals. He has also served on several grant review study sections and special emphasis panels for the NIH. Dr. Salek-Ardakani holds a Ph.D. in oncology and M.Sc. in immunology and immunogenetics from the Cancer Research UK Manchester Institute.

    About Janux Therapeutics

    Janux Therapeutics is an innovative biopharmaceutical company developing next-generation therapeutics based on its proprietary Tumor Activated T Cell Engager (TRACTr) platform technology to better treat patients suffering from cancer. Janux's initial focus is on developing a novel class of T cell engagers (TCEs), and its lead product candidates are designed to target clinically validated drug targets. While TCE therapeutics have displayed potent anti-tumor activity in hematological cancers, developing TCEs to treat solid tumors have faced challenges due to the limitations of prior TCE technologies, namely (i) overactivation of the immune system leading to cytokine release syndrome, (ii) on-target, healthy tissue toxicities, and (iii) poor pharmacokinetics leading to short half-life. Janux is using its TRACTr platform technology to engineer product candidates designed to overcome these limitations. Janux is developing a broad pipeline with lead programs targeting prostate-specific membrane antigen (PSMA), epidermal growth factor receptor (EGFR), and trophoblast cell surface antigen 2 (TROP2), with all of its programs currently in the IND-enabling or discovery stage. For more info, www.januxrx.com.

    Forward-Looking Statements

    This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, Janux's ability to bring new treatments to cancer patients in need and the progress and expected timing of Kura's drug development programs. Factors that may cause actual results to differ materially include the risk that compounds that appear promising in early research do not demonstrate safety and/or efficacy in later preclinical studies or clinical trials, the risk that Janux may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings and applications, risks associated with reliance on third parties to successfully conduct clinical trials, the risks associated with reliance on outside financing to meet capital requirements, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "promise," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Janux faces, please refer to Janux's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Janux assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise.

    See also: HOW TO BUY JANUX THERAPEUTICS IPO (JANX) STOCK

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  5. Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000 shares of its common stock, which includes 1,710,000 shares sold pursuant to the exercise in full by the underwriters of their option to purchase additional shares, at a price to the public of $17.00 per share. Including the option exercise, the aggregate gross proceeds to Janux from the offering were approximately…

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000

    Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a biopharmaceutical company developing novel T cell engager immunotherapies, today announced the closing of its previously announced initial public offering of 13,110,000 shares of its common stock, which includes 1,710,000 shares sold pursuant to the exercise in full by the underwriters of their option to purchase additional shares, at a price to the public of $17.00 per share. Including the option exercise, the aggregate gross proceeds to Janux from the offering were approximately $222.9 million, before deducting the underwriting discounts and commissions and offering expenses. The shares began trading on the Nasdaq Global Market on June 11, 2021, under the ticker symbol "JANX."

    BofA Securities, Cowen and Evercore ISI acted as joint book-running managers for the offering. H.C. Wainwright & Co. acted as lead manager for the offering.

    Registration statements relating to the offering of these securities have been filed with the Securities and Exchange Commission (SEC) and became effective on June 10, 2021. Copies of the registration statements can be accessed through the SEC's website at www.sec.gov. This offering was made only by means of a written prospectus. Copies of the final prospectus relating to the initial public offering may be obtained from: BofA Securities, Attention: Prospectus Department, NC1-004-03-43, 200 North College Street, 3rd Floor, Charlotte, NC 28255-0001 or by email at dg.prospectus_requests@bofa.com; Cowen and Company, LLC, c/o Broadridge Financial Solutions, Attention: Prospectus Department, 1155 Long Island Avenue, Edgewood, NY 11717, or by telephone at (833) 297-2926 or by email at PostSaleManualRequests@broadridge.com; or Evercore Group L.L.C., Attention: Equity Capital Markets, 55 East 52nd Street, 36th Floor, New York, NY 10055, or by telephone at (888) 474-0200 or by email at ecm.prospectus@evercore.com.

    This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

    See also: HOW TO BUY JANUX THERAPEUTICS IPO (JANX) STOCK

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