IMAB I-MAB

29.46
+0.22  (+1%)
Previous Close 29.24
Open 29.3
52 Week Low 9.3
52 Week High 35
Market Cap $1,703,641,604
Shares 57,828,975
Float 2,148,350
Enterprise Value $630,837,889
Volume 63,139
Av. Daily Volume 70,167
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Upcoming Catalysts

Drug Stage Catalyst Date
TJC4
Advanced cancers
Phase 1
Phase 1
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TJD5
Advanced solid tumors
Phase 1
Phase 1
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Drug Pipeline

Drug Stage Notes
Enoblituzumab
Head and neck cancer
Phase 2
Phase 2
Phase 2 trial to be initiated 1Q 2021.
TJM2
COVID-19
Phase 1/2
Phase 1/2
Phase 1 interim data released May 27, 2020.
TJM2
Rheumatoid arthritis
Phase 1b
Phase 1b
Phase 1b trial to commence 2Q 2020.
TJ202/MOR202
Multiple Myeloma (MM) - second line
Phase 3
Phase 3
Phase 3 ongoing.
Eftansomatropin (TJ101)
Growth hormone deficiency
Phase 3
Phase 3
Phase 3 IND to be filed 2020.
TJ202/MOR202
Systemic lupus erythematosus
Phase 1b
Phase 1b
Phase 1b trial planned.
TJ202/MOR202
Third-line multiple myeloma
Phase 3
Phase 3
Phase 3 ongoing (China).

Latest News

  1. SHANGHAI and GAITHERSBURG, Md., Aug. 6, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, today announced that it will report financial results for the six months ended June 30, 2020 before the market opens on Monday, August 31, 2020, and host a conference call to discuss the results and provide a corporate update at 8:00 a.m. ET.

    I-MAB Logo (PRNewsfoto/I-Mab Biopharma)

    Conference Call and Webcast Information

    I-Mab will host a live conference call and webcast on August 31, 2020 at 8:00 a.m. ET. Participants must register in advance of the conference call. Details are as follows:

    SHANGHAI and GAITHERSBURG, Md., Aug. 6, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, today announced that it will report financial results for the six months ended June 30, 2020 before the market opens on Monday, August 31, 2020, and host a conference call to discuss the results and provide a corporate update at 8:00 a.m. ET.

    I-MAB Logo (PRNewsfoto/I-Mab Biopharma)

    Conference Call and Webcast Information

    I-Mab will host a live conference call and webcast on August 31, 2020 at 8:00 a.m. ET. Participants must register in advance of the conference call. Details are as follows:

    Registration Link:

    http://apac.directeventreg.com/registration/event/8959387

    Conference ID:

    8959387

    Upon registering, each participant will receive a dial-in number, Direct Event passcode, and a unique access PIN, which can be used to join the conference call.

    A webcast replay will be archived on the Company's website for one year after the conclusion of the call at http://ir.i-mabbiopharma.com.

    A telephone replay will be available approximately two hours after the conclusion of the call. To access the replay, please call +1-855-452-5696 (U.S.), +61-2-8199-0299 (International), 400-632-2162 (Mainland China), or 800-963-117 (Hong Kong). The conference ID number for the replay is 8959387.

    About I-Mab

    I-Mab (NASDAQ:IMAB) is a dynamic, global biotech company exclusively focused on developing biologics of novel or highly differentiated in the therapeutic areas of immuno-oncology and autoimmune diseases. The Company's mission is to bring transformational medicines to patients through innovation. I-Mab's innovative pipeline of more than 10 clinical and pre-clinical stage drug candidates is driven by the Company's Fast-to-PoC (Proof-of-Concept) and Fast-to-Market development strategies through internal R&D and global partnerships. The Company is on track to become a fully integrated end-to-end global biopharmaceutical company with cutting-edge discovery platforms, proven preclinical and clinical development expertise, and world-class GMP manufacturing capabilities. I-Mab has offices in Beijing, Shanghai, Hong Kong and Maryland, United States. For more information, please visit http://ir.i-mabbiopharma.com

    For more information, please contact:

    I-Mab

    Jielun Zhu, CFO

    E-mail:

    Office line: +86 21 6057 8000

    Gigi Feng, Vice President and Global Head of Corporate Communications

    E-mail: 

    Office line: +86 21 6057 8000

    Investor Inquiries:

    Burns McClellan, Inc. (Americas and Europe)

    Steve Klass

    E-mail:

    Office line: +1 212 213 0006

    The Piacente Group, Inc. (Asia)

    Emilie Wu

    E-mail:

    Office line: + 86 21 6039 8363

    Cision View original content to download multimedia:http://www.prnewswire.com/news-releases/i-mab-to-report-financial-results-for-the-six-months-ended-june-30-2020-and-provide-corporate-update-on-august-31-2020-301107641.html

    SOURCE I-Mab

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  2. SHANGHAI and GAITHERSBERG, Md., Aug. 4, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, today announced that the China National Medical Products Administration (NMPA) has accepted its pivotal trial application for eftansomatropin (also known as TJ101) as a weekly treatment for growth hormone deficiency in pediatric patients (PGHD).

    Eftansomatropin is an innovative long-acting recombinant human growth hormone (rhGH) with a novel molecular format utilizing Genexine's patented half-life extension hyFc® fusion technology, which stimulates the production of insulin-like growth factor 1 (IGF-1) in the liver, alongside growth-stimulating effects on a variety of tissues, including osteoblast and chondrocyte activities that stimulate bone growth. Additionally, preliminary research and trials have proved that as a natural protein based rhGH, eftansomatropin has not shown safety concerns typically associated with conventional pegylated rhGH drugs on the market, while maintaining comparable efficacy.

    The Phase 3 trial is a multi-center, randomized, open-label, active-controlled clinical study designed to assess the safety, efficacy and pharmacokinetics of eftansomatropin in PGHD. The primary objective is to demonstrate non-inferiority of eftansomatropin administered in subcutaneous injection, compared to the active control Norditropin® (somatropin), a daily rhGH marketed in China. About 165 subjects will be enrolled and treated in the study.

    "The China NMPA's acceptance of this pivotal IND for eftansomatropin represents an important step towards bringing this innovative product to the Chinese market as planned," said Dr. Joan Shen, CEO of I-Mab. "With eftansomatropin, we will be able to potentially address a substantial unmet medical need with a safer, highly differentiated, and convenient therapy for pediatric patients suffering from the growth hormone deficiency."

    The Company owns the rights of eftansomatropin from Genexine Inc. (KOSDAQ: 095700) for development, manufacturing and commercialization in China. Genexine has previously completed three clinical trials with eftansomatropin in Europe and Asia, including one Phase 1 trial in healthy adult volunteers, one Phase 1b/2 multi-regional trial in adults with growth hormone deficiency (NCT02946606), and one Phase 2 multi-regional trial in PGHD (NCT03309891). Overall, eftansomatropin was shown to be well-tolerated, and has met clinical efficacy endpoints by weekly or twice-monthly administration.

    According to Frost & Sullivan, PGHD affected approximately 3.4 million patients in Greater China, but only 3.7% of all PGHD patients were receiving growth hormone replacement therapy, which primarily consists of daily injections of rhGH. Recombinant human growth hormone therapy has been included in the National Reimbursement Drug List in China.

    About eftansomatropin

    Eftansomatropin is a potential highly differentiated long-acting recombinant human growth hormone being developed as a more convenient and effective therapy for growth hormone deficiency. Like endogenous growth hormone, eftansomatropin stimulates the production of insulin-like growth factor 1 in the liver, which has growth-stimulating effects on a variety of tissues, including osteoblast and chondrocyte activities that stimulate bone growth. IGF-1 is a reliable pharmacodynamic marker and the key mediator of growth-promoting activity of eftansomatropin. Eftansomatropin is based on Genexine's patented hyFc® technology. The hyFc part consists of a portion of human immunoglobulin D ("IgD") and G4 ("IgG4"). The former contains a flexible hinge, and the latter is responsible for half-life extension through neonatal Fc receptor ("FcRn")-mediated recycling.

    About I-Mab

    I-Mab (NASDAQ:IMAB) is a dynamic, global biotech company exclusively focused on developing biologics of novel or highly differentiated in the therapeutic areas of immuno-oncology and autoimmune diseases. The Company's mission is to bring transformational medicines to patients through innovation. I-Mab's innovative pipeline of more than 10 clinical and pre-clinical stage drug candidates is driven by the Company's Fast-to-PoC (Proof-of-Concept) and Fast-to-Market development strategies through internal R&D and global partnerships. The Company is on track to become a fully integrated end-to-end global biopharmaceutical company with cutting-edge discovery platforms, proven preclinical and clinical development expertise, and world-class GMP manufacturing capabilities. I-Mab has offices in Beijing, Shanghai, Hong Kong and Maryland, United States. For more information, please visit http://ir.i-mabbiopharma.com

    Forward Looking Statements

    This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 and other federal securities laws, including statements regarding data from the eftansomatropin (TJ101) Phase III trial of pediatric growth hormone deficiency, the potential implications of clinical data for patients, and I-Mab's advancement of, and anticipated clinical development, regulatory milestones and commercialization of eftansomatropin (TJ101). Actual results may differ materially from those indicated in the forward-looking statements as a result of various important factors, including but not limited to I-Mab's ability to demonstrate the safety and efficacy of its drug candidates; the clinical results for its drug candidates, which may not support further development or NDA/BLA approval; the content and timing of decisions made by the relevant regulatory authorities regarding regulatory approval of I-Mab's drug candidates; I-Mab's ability to achieve commercial success for its drug candidates, if approved; I-Mab's ability to obtain and maintain protection of intellectual property for its technology and drugs; I-Mab's reliance on third parties to conduct drug development, manufacturing and other services; I-Mab's limited operating history and I-Mab's ability to obtain additional funding for operations and to complete the development and commercialization of its drug candidates; and the impact of the COVID-19 pandemic on the Company's clinical development, commercial and other operations, as well as those risks more fully discussed in the "Risk Factors" section in I-Mab's most recent annual report on Form 20-F, as well as discussions of potential risks, uncertainties, and other important factors in I-Mab's subsequent filings with the U.S. Securities and Exchange Commission. All forward-looking statements are based on information currently available to I-Mab, and I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

    For more information, please contact:

    I-Mab

    Jielun Zhu, CFO

    E-mail:

    Office line: +86 21 6057 8000

    Gigi Feng, Vice President and Global Head of Corporate Communications

    Email:

    Office line: +86 21 6057 8000

    Investor Inquiries:

    Burns McClellan, Inc. (Americas and Europe)

    Steve Klass

    E-mail:

    Office line: +1 212 213 0006

    The Piacente Group, Inc. (Asia)

    Emilie Wu

    E-mail:

    Office line: +86 21 6039 8363

     

    Cision View original content to download multimedia:http://www.prnewswire.com/news-releases/china-nmpa-accepts-ind-application-for-eftansomatropin-pivotal-trial-in-pediatric-patients-with-growth-hormone-deficiency-301105667.html

    SOURCE I-Mab

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  3. SHANGHAI and GAITHERSBERG, Md., July 28, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, today announced the appointment of Mr. Ivan Yifei Zhu as its Chief Commercial Officer, effective August 10, 2020. Mr. Zhu will report directly to Dr. Jingwu Zang, Founder, Honorary Chairman and Director of I-Mab. In this role, Mr. Zhu will focus on building and developing I-Mab's commercialization infrastructure and strategies, and preparing the Company for upcoming product launches.

    "I-Mab is at a turning point as we rapidly advance our late-stage clinical pipeline and move toward commercialization," said Dr. Jingwu Zang, Founder, Honorary Chairman and Director of I-Mab. "Ivan is a proven commercial leader in China with an impressive track record of building commercial teams and leading successful product launches at domestic and international pharma companies. His addition to our company will greatly accelerate our transition to I-Mab 2.0 -- a fully-integrated global biopharmaceutical company."

    Mr. Zhu has more than 20 years of successful commercialization experience at global and domestic pharma and biotech companies. Prior to joining I-Mab, he served as Vice President and General Manager of the sales division of Qilu Pharmaceutical Group where he managed the company's sales and marketing team. During his tenure at Qilu, he successfully led the launch of the first domestic biosimilar product of bevacizumab. Mr. Zhu has also served as the Chief Commercial Officer of BeiGene where he played an instrumental role in the expansion of BeiGene's commercialization team and the implementation of its commercialization strategies.

    Mr. Zhu also worked for Xi'an Janssen for more than 20 years where he held various senior management positions. During this period, he built and managed numerous business units, covering a wide range of therapeutic areas including oncology, immunotherapy, skin diseases, infectious diseases and the central nervous system.

    "I am extremely impressed by I-Mab's highly-differentiated, globally competitive product pipeline, as well as its world-class management team," said Mr. Zhu. "I am excited to join Dr. Zang and his team in addressing significant unmet needs for patients worldwide, and contributing to the Company's strategic transformation and future development."

    About I-Mab

    I-Mab (NASDAQ:IMAB) is a dynamic, global biotech company exclusively focused on developing biologics of novel or highly differentiated in the therapeutic areas of immuno-oncology and autoimmune diseases. The Company's mission is to bring transformational medicines to patients through innovation. I-Mab's innovative pipeline of more than 10 clinical and pre-clinical stage drug candidates is driven by the Company's Fast-to-PoC (Proof-of-Concept) and Fast-to-Market development strategies through internal R&D and global partnerships. The Company is on track to become a fully integrated end-to-end global biopharmaceutical company with cutting-edge discovery platforms, proven preclinical and clinical development expertise, and world-class GMP manufacturing capabilities. I-Mab has offices in Beijing, Shanghai, Hong Kong and Maryland, United States. For more information, please visit http://ir.i-mabbiopharma.com

    Forward Looking Statements

    This press release includes certain disclosures which contain "forward-looking statements." You can identify forward-looking statements because they contain words such as "anticipate" and "expected." Forward-looking statements are based on I-Mab's current expectations and assumptions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that may differ materially from those contemplated by the forward-looking statements, which are neither statements of historical fact nor guarantees or assurances of future performance. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in filings with the U.S. Securities and Exchange Commission. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

    For more information, please contact:

    I-Mab

    Jielun Zhu, CFO

    E-mail:

    Office line: +86 21 6057 8000

    Gigi Feng, Vice President and Global Head of Corporate Communications

    Email:

    Office line: +86 21 6057 8000

    Investor Inquiries:

    Burns McClellan, Inc. (Americas and Europe)

    Steve Klass

    E-mail:

    Office line: +1 212 213 0006

    The Piacente Group, Inc. (Asia)

    Emilie Wu

    E-mail:

    Office line: +86 21 6039 8363

    Cision View original content to download multimedia:http://www.prnewswire.com/news-releases/i-mab-drives-commercialization-strategy-with-appointment-of-ivan-yifei-zhu-as-chief-commercial-officer-301100941.html

    SOURCE I-Mab

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  4. SHANGHAI and GAITHERSBURG, Md., July 15, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, today announced that its Board of Directors has authorized a stock repurchase program under which the Company may repurchase up to US$20 million of its ordinary shares in the form of American depositary shares.

    "I am pleased to announce this stock repurchase program," said Dr. Jingwu Zang, M.D., Ph.D., Founder, Honorary Chairman and Director of the Company. "This program underscores our full confidence in the potential of I-Mab's highly differentiated, globally competitive pipeline. We believe repurchase of I-Mab's common stock is consistent with our focus on enhancing and delivering long-term shareholder value."

    Repurchases, if any, under the program will be made at the discretion of management, and will depend upon market pricing and conditions, business, legal, accounting and other considerations. Any such share purchases will be made by the Company from time to time in open market transactions, or otherwise in compliance with Rule 10b-18 under the Securities Exchange Act of 1934, or pursuant to a trading plan adopted in accordance with Rule 10b5–1 of the Securities Exchange Act of 1934.

    The repurchase program is effective upon and from the date on which a formal stock repurchase plan engagement agreement is signed with a qualified broker-dealer(s), and terminates over a twelve-month period depending upon market and economic conditions, and other factors including price, legal and regulatory requirements and capital availability. The program does not obligate I-Mab to acquire any particular number of American depositary shares, and the program may be modified or suspended at any time at the management's discretion.

    About I-Mab

    I-Mab (NASDAQ:IMAB) is a dynamic, global biotech company exclusively focused on developing biologics of novel or highly differentiated in the therapeutic areas of immuno-oncology and autoimmune diseases. Company's mission is to bring transformational medicines to patients through innovation. I-Mab's innovative pipeline of more than 10 clinical and pre-clinical stage drug candidates is driven by the Company's Fast-to-PoC (Proof-of-Concept) and Fast-to-Market development strategies through internal R&D and global partnerships. The Company is on track to become a fully integrated end-to-end global biopharmaceutical company with cutting-edge discovery platforms, proven preclinical and clinical development expertise, and world-class GMP manufacturing capabilities. I-Mab has offices in China and the United States. For more information, please visit http://ir.i-mabbiopharma.com/.

    Forward Looking Statements

    This press release includes certain disclosures which contain "forward-looking statements." You can identify forward-looking statements because they contain words such as "anticipate" and "expected." Forward-looking statements are based on I-Mab's current expectations and assumptions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that may differ materially from those contemplated by the forward-looking statements, which are neither statements of historical fact nor guarantees or assurances of future performance. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in filings with the U.S. Securities and Exchange Commission. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

    For more information, please contact:

    I-Mab

    Jielun Zhu, CFO

    E-mail:

    Office line: +86 21 6057 8000

    Gigi Feng, Vice President and Global Head of Corporate Communications

    E-mail:

    Office line: +86 21 6057 8000

    Investor Inquiries

    Burns McClellan, Inc. (Americas and Europe)

    Steve Klass

    E-mail:

    Office line: +1 212 213 0006

    The Piacente Group, Inc. (Asia)

    Emilie Wu

    E-mail:

    Office line: +86 21 6039 8363

    Cision View original content to download multimedia:http://www.prnewswire.com/news-releases/i-mab-announces-authorization-of-stock-repurchase-program-up-to-20-million-301094129.html

    SOURCE I-Mab

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  5. SHANGHAI and GAITHERSBURG, Md., June 12, 2020 /PRNewswire/ -- I-Mab (the "Company") (NASDAQ:IMAB), a clinical stage biopharmaceutical company committed to the discovery, development and commercialization of novel biologics, will be presenting preclinical data on a newly developed, novel asset TJ-CD4B, at the American Association for Cancer Research (AACR) Virtual Annual Meeting II on June 22-24, 2020.

    TJ-CD4B, also known as ABL111, is a Claudin 18.2 and 4-1BB bispecific antibody jointly developed with South Korea-based ABL Bio, Inc. (Kosdaq: 298380, hereafter "ABL"). TJ-CD4B is from I-Mab's emerging bispecific antibody portfolio designed to create novel drug molecules that synergize two pathways for better clinical efficacy. By linking with an antibody against Claudin 18.2, a gastric- and pancreatic-specific cancer antigen, TJ-CD4B/ABL111 is uniquely structured to supercharge T cells in a Claudin 18.2-dependent manner, enhancing anti-tumor immunity while potentially minimizing toxicity.

    The pre-clinical validation of TJ-CD4B/ABL111 to be presented at AACR signifies the overall progress of I-Mab's bispecific antibody portfolio, reflecting Company's discovery and CMC capabilities to engineer novel molecules with combined target specificities. I-Mab plans to advance more novel bispecific antibodies towards clinical development stage, following the lead of TJ-CD4B/ABL111.

    The poster presentation (Abstract #5644) is available for on-demand viewing starting 9:00 am EDT, 22 June, and will remain for viewing by registered attendees for at least three months after the virtual meeting. 

    The abstract is available online at:

    https://www.abstractsonline.com/pp8/#!/9045/sessions/5644/1

    About I-Mab

    I-Mab (NASDAQ:IMAB) is a dynamic, global biotech company exclusively focused on developing biologics of novel or highly differentiated in the therapeutic areas of immuno-oncology and autoimmune diseases. Company's mission is to bring transformational medicines to patients through innovation. I-Mab's innovative pipeline of more than 10 clinical and pre-clinical stage drug candidates is driven by the Company's Fast-to-PoC (Proof-of-Concept) and Fast-to-Market development strategies through internal R&D and global partnerships. The Company is on track to become a fully integrated end-to-end global biopharmaceutical company with cutting-edge discovery platforms, proven preclinical and clinical development expertise, and world-class GMP manufacturing capabilities. I-Mab has offices in China and the United States. For more information, please visit http://ir.i-mabbiopharma.com/.

    Forward Looking Statements

    This press release includes certain disclosures which contain "forward-looking statements." You can identify forward-looking statements because they contain words such as "anticipate" and "expected." Forward-looking statements are based on I-Mab's current expectations and assumptions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that may differ materially from those contemplated by the forward-looking statements, which are neither statements of historical fact nor guarantees or assurances of future performance. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in filings with the U.S. Securities and Exchange Commission. I-Mab undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required by law.

    For more information, please contact:

    I-Mab

    Jielun Zhu, CFO

    E-mail:

    Office line: +86 21 6057 8000

    Gigi Feng, Vice President and Global Head of Corporate Communications

    E-mail:

    Office line: +86 21 6057 8000

    Investor Inquiries:

    Burns McClellan, Inc. (Americas and Europe)

    Steve Klass

    E-mail:

    Office line: +1 212 213 0006

    The Piacente Group, Inc. (Asia)

    Emilie Wu

    E-mail:

    Office line: + 86 21 6039 8363

     

    Cision View original content to download multimedia:http://www.prnewswire.com/news-releases/i-mab-and-abl-bio-to-present-preclinical-data-for-joint-bispecific-antibody-program-at-the-2020-american-association-for-cancer-research-virtual-meeting-ii-301075057.html

    SOURCE I-Mab

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