IGMS IGM Biosciences Inc.

87.43
+3.48  (+4%)
Previous Close 83.95
Open 85.96
52 Week Low 27.55
52 Week High 133
Market Cap $2,790,924,285
Shares 31,921,815
Float 8,377,254
Enterprise Value $2,855,320,661
Volume 142,596
Av. Daily Volume 215,933
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Upcoming Catalysts

Drug Stage Catalyst Date
IGM-8444
Solid Cancers and Non-Hodgkin’s Lymphoma
Phase 1
Phase 1
Premium membership is required to view catalyst dates, analyst ratings, earnings dates and cash burn data. Click here to unlock and sign up to a 14-day FREE TRIAL.

Drug Pipeline

Drug Stage Notes
IGM-2323
Relapsed/refractory B cell Non-Hodgkin’s lymphoma (NHL)
Phase 1
Phase 1
Phase 1 initial data presented at ASH December 5, 2020. 2/14 complete responses.

Latest News

  1. STOCKHOLM, Feb. 26, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: MVIR) today announces that the number of shares and votes in Medivir has changed during February 2021 as a result of the previously announced rights issue and over-allotment option and which in total resulted in an increase of 27,847,833 class B shares.

    Today, the last trading day of the month, there are in total 52,135,651 shares in Medivir, of which all are class B shares with in total 52,135,651 corresponding voting rights.

    For additional information, please contact
    Yilmaz Mahshid, CEO
    Telephone: +46 8 5468 3100
    E-mail:

    Magnus Christensen, CFO
    Telephone: +46 8 5468 3100
    E-mail:

    This information is such information

    STOCKHOLM, Feb. 26, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: MVIR) today announces that the number of shares and votes in Medivir has changed during February 2021 as a result of the previously announced rights issue and over-allotment option and which in total resulted in an increase of 27,847,833 class B shares.

    Today, the last trading day of the month, there are in total 52,135,651 shares in Medivir, of which all are class B shares with in total 52,135,651 corresponding voting rights.

    For additional information, please contact

    Yilmaz Mahshid, CEO

    Telephone: +46 8 5468 3100

    E-mail:

    Magnus Christensen, CFO

    Telephone: +46 8 5468 3100

    E-mail:

    This information is such information that Medivir AB (publ) is obliged to make public pursuant to the Swedish Financial Instruments Trading Act. The information was submitted for publication on 26 February 2021 at 08:00 CET through the agency of the contact persons set out above.

    Medivir in brief

    Medivir develops innovative drugs with a focus on cancer where the unmet medical needs are high. The drug candidates are directed toward indication areas where available therapies are limited or missing and there are great opportunities to offer significant improvements to patients. Medivir is focusing on the development of MIV-818, a pro-drug designed to selectively treat liver cancer cells and to minimize side effects. 

    Collaborations and partnerships are important parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences (NASDAQ:IGMS) to be developed in combination with IGM-antibodies for the treatment of solid tumors. Medivir's share (TICKER:MVIR) is listed on Nasdaq Stockholm's Small Cap list. www.medivir.com.

    This information was brought to you by Cision http://news.cision.com

    https://news.cision.com/medivir/r/number-of-shares-and-votes-in-medivir,c3296336

    The following files are available for download:

    Cision View original content:http://www.prnewswire.com/news-releases/number-of-shares-and-votes-in-medivir-301236305.html

    SOURCE Medivir

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  2. STOCKHOLM, Sweden, Feb. 10, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: MVIR) announced today that it had entered into a license agreement with Ubiquigent Limited (Ubiquigent) for Medivir's preclinical USP7 research program. Under the terms of the agreement, Medivir has granted Ubiquigent an exclusive worldwide license to develop and commercialize the program including all associated compounds across any therapeutic indication(s) in return for agreed revenue share upon successful development or commercialization by Ubiquigent.

    Ubiquitin specific peptidase 7 (USP7) is a deubiquitylating (DUB) enzyme that has been linked to cancer due to its ability to deubiquitylate substrates that regulate key oncogenic, DNA-damage response and tumor…

    STOCKHOLM, Sweden, Feb. 10, 2021 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: MVIR) announced today that it had entered into a license agreement with Ubiquigent Limited (Ubiquigent) for Medivir's preclinical USP7 research program. Under the terms of the agreement, Medivir has granted Ubiquigent an exclusive worldwide license to develop and commercialize the program including all associated compounds across any therapeutic indication(s) in return for agreed revenue share upon successful development or commercialization by Ubiquigent.

    Ubiquitin specific peptidase 7 (USP7) is a deubiquitylating (DUB) enzyme that has been linked to cancer due to its ability to deubiquitylate substrates that regulate key oncogenic, DNA-damage response and tumor initiating pathways. Inhibitors of USP7 therefore represent an exciting opportunity to be effective treatments in targeted patient populations in oncology either as a monotherapy or in combination therapies. 

    Ubiquigent has established itself as a respected partner in the DUB field with a strong track record in the development of small molecule DUB inhibitors both through supporting the drug discovery efforts of its partners and by the strengthening of its own portfolio of novel DUB inhibitors. This latest agreement builds upon an existing long-term relationship between the parties and directly supports Ubiquigent's strategy to build and commercialize a strong IP portfolio of novel DUB inhibitors.

    -  "We are very pleased that Medivir's research program aimed at the development of USP7 inhibitors has been licensed to Ubiquigent. With an excellent track-record and strong research capabilities within the DUB field, we believe that Ubiquigent is perfectly positioned to further progress the USP7 program. We look forward to Ubiquigent's successful development of the USP7 assets", said Fredrik Öberg, CSO at Medivir.

    -  "This agreement with Medivir is a tremendous endorsement of our approach and represents a significant milestone for Ubiquigent. We look forward to continuing to support our partners in the development of exciting new therapeutics around USP7 and other DUBs of therapeutic relevance by providing a highly druggable approach to protein degradation", said Ubiquigent's Managing Director, Jason Mundin.*



    For further information, please contact:

    Yilmaz Mahshid, CEO, Medivir AB, phone: +46 (0)8 5468 3100.

    vir.com

    Jason Mundin, Managing Director, Ubiquigent Ltd, phone: +44 (0) 7976 000683

    E-mail:



    About Medivir



    Medivir develops innovative drugs with a focus on cancer where the unmet medical needs are high. The drug candidates are directed toward indication areas where available therapies are limited or missing and there are great opportunities to offer significant improvements to patients. Medivir is focusing on the development of MIV-818, a pro-drug designed to selectively treat liver cancer cells and to minimize side effects.  



    Collaborations and partnerships are important parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences (NASDAQ:IGMS) to be developed in combination with IGM-antibodies for the treatment of solid tumors. Medivir's share (TICKER:MVIR) is listed on Nasdaq Stockholm's Small Cap list. www.medivir.com



    About Ubiquigent



    Ubiquigent Limited enables and supports protein degradation focused drug discovery via modulation and exploitation of the ubiquitin system. Our chemistry and biology platforms allow us to design and develop novel compounds as part of strategic partnerships. In parallel Ubiquigent also provides access to our platforms and capabilities for the evaluation of our partners' compounds.



    About deubiquitylating (DUB) enzymes



    The attachment of ubiquitin, or chains of ubiquitin, to a substrate protein may confer on it a specific cellular signalling function or target that protein for degradation - subject to the type of chain attached.  The deubiquitylating (DUB) enzymes are a class of druggable enzymes that remove this ubiquitylation marker from proteins thereby `rescuing' them from degradation and/or reversing their modulation of signalling pathways.  The inhibition of DUBs therefore offers another, largely unexploited, route to achieve the degradation of therapeutically relevant protein targets.  For more information please visit www.ubiquigent.com

    This information was brought to you by Cision http://news.cision.com

    https://news.cision.com/medivir/r/medivir-enters-into-licensing-agreement-with-ubiquigent-for-preclinical-program-usp7,c3283937

    The following files are available for download:

     

    Cision View original content:http://www.prnewswire.com/news-releases/medivir-enters-into-licensing-agreement-with-ubiquigent-for-preclinical-program-usp7-301226033.html

    SOURCE Medivir

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  3. Ubiquigent Limited (Ubiquigent) announced today that it has entered into a license agreement with Medivir AB (Nasdaq Stockholm: MVIR) for Medivir's preclinical USP7 research program. Under the terms of the agreement, Medivir has granted Ubiquigent an exclusive worldwide license to develop and commercialize the program including all associated compounds across any therapeutic indication(s) in return for agreed revenue share upon successful development or commercialization by Ubiquigent.

    Ubiquitin specific peptidase 7 (USP7) is a deubiquitylating (DUB) enzyme that has been linked to cancer due to its ability to deubiquitylate substrates that regulate key oncogenic, DNA-damage response and tumor initiating pathways. Inhibitors of USP7 therefore…

    Ubiquigent Limited (Ubiquigent) announced today that it has entered into a license agreement with Medivir AB (Nasdaq Stockholm: MVIR) for Medivir's preclinical USP7 research program. Under the terms of the agreement, Medivir has granted Ubiquigent an exclusive worldwide license to develop and commercialize the program including all associated compounds across any therapeutic indication(s) in return for agreed revenue share upon successful development or commercialization by Ubiquigent.

    Ubiquitin specific peptidase 7 (USP7) is a deubiquitylating (DUB) enzyme that has been linked to cancer due to its ability to deubiquitylate substrates that regulate key oncogenic, DNA-damage response and tumor initiating pathways. Inhibitors of USP7 therefore represent an exciting opportunity to be effective treatments in targeted patient populations in oncology either as a monotherapy or in combination therapies.

    Ubiquigent has established itself as a respected partner in the DUB field with a strong track record in the development of small molecule DUB inhibitors both through supporting the drug discovery efforts of its partners and by the strengthening of its own portfolio of novel DUB inhibitors. This latest agreement builds upon an existing long-term relationship between the parties and directly supports Ubiquigent's strategy to build and commercialize a strong IP portfolio of novel DUB inhibitors.

    - : "We are very pleased that Medivir's research program aimed at the development of USP7 inhibitors has been licensed to Ubiquigent. With an excellent track-record and strong research capabilities within the DUB field, we believe that Ubiquigent is perfectly positioned to further progress the USP7 program. We look forward to Ubiquigent's successful development of the USP7 assets", said Fredrik Öberg, CSO at Medivir.

    - : "This agreement with Medivir is a tremendous endorsement of our approach and represents a significant milestone for Ubiquigent. We look forward to continuing to support our partners in the development of exciting new therapeutics around USP7 and other DUBs of therapeutic relevance by providing a highly druggable approach to protein degradation", said Ubiquigent's Managing Director, Jason Mundin.

    About Medivir

    Medivir develops innovative drugs with a focus on cancer where the unmet medical needs are high. The drug candidates are directed toward indication areas where available therapies are limited or missing and there are great opportunities to offer significant improvements to patients. Medivir is focusing on the development of MIV-818, a pro-drug designed to selectively treat liver cancer cells and to minimize side effects.

    Collaborations and partnerships are important parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences (NASDAQ:IGMS) to be developed in combination with IGM-8444 for the treatment of solid tumors. Medivir's share (TICKER:MVIR) is listed on Nasdaq Stockholm's Small Cap list. www.medivir.com

    About Ubiquigent

    Ubiquigent Limited enables and supports protein degradation focused drug discovery via modulation and exploitation of the ubiquitin system. Our chemistry and biology platforms allow us to design and develop novel compounds as part of strategic partnerships. In parallel Ubiquigent also provides access to our platforms and capabilities for the evaluation of our partners' compounds.

    About deubiquitylating (DUB) enzymes

    The attachment of ubiquitin, or chains of ubiquitin, to a substrate protein may confer on it a specific cellular signalling function or target that protein for degradation - subject to the type of chain attached. The deubiquitylating (DUB) enzymes are a class of druggable enzymes that remove this ubiquitylation marker from proteins thereby ‘rescuing' them from degradation and/or reversing their modulation of signalling pathways. The inhibition of DUBs therefore offers another, largely unexploited, route to achieve the degradation of therapeutically relevant protein targets. For more information please visit www.ubiquigent.com

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  4. HUDDINGE, Sweden, Feb. 7, 2021 /PRNewswire/ -- The Board of Directors in Medivir AB (publ) ("Medivir" or the "Company") has decided to summon an extraordinary general meeting on 11 March 2021 to propose a directed issue (the "Directed Issue") to the Company's existing specialist investor LINC AB ("LINC"), controlled by the Company's board member Bengt Julander.

    In the rights issue, from which the preliminary results was announced on 5 February 2021 (the "Rights Issue"), Bengt Julander (through LINC) among others entered into subscription and guarantee commitments. The Rights Issue was substantially oversubscribed and no guarantee commitments needed to be utilized. Through an over-allotment option related to the Rights Issue (the "Over-allotment…

    HUDDINGE, Sweden, Feb. 7, 2021 /PRNewswire/ -- The Board of Directors in Medivir AB (publ) ("Medivir" or the "Company") has decided to summon an extraordinary general meeting on 11 March 2021 to propose a directed issue (the "Directed Issue") to the Company's existing specialist investor LINC AB ("LINC"), controlled by the Company's board member Bengt Julander.

    In the rights issue, from which the preliminary results was announced on 5 February 2021 (the "Rights Issue"), Bengt Julander (through LINC) among others entered into subscription and guarantee commitments. The Rights Issue was substantially oversubscribed and no guarantee commitments needed to be utilized. Through an over-allotment option related to the Rights Issue (the "Over-allotment Option") the specialist investor Healthinvest Partners AB was added to the Company's shareholder base. As a result of the strong interest in the Rights Issue and in order to further strengthen the Company's institutional shareholder base, the Board of Directors has decided to summon an extraordinary general meeting on 11 March 2021 to propose a directed issue of approximately SEK 28 million to Bengt Julander (through LINC).

    Since the Directed Issue is directed to a company controlled by board member Bengt Julander, part of the Company's category of related parties referenced in the Swedish Companies Act (sw. ABL) chapter 16 (2005:551), the Directed Issue requires approval by the Company's shareholders representing at least nine tenths of the votes casted as well as the shares represented at the extraordinary general meeting on 11 March 2021, for which a notice will be published separately. Bengt Julander did not participate in the decision regarding the Directed Issue by the Board of Directors.

    The extraordinary general meeting will decide on the proposal to issue a total of 3,600,000 new series B shares, directed to Bengt Julander (through LINC), at a subscription price of SEK 7.73 per share, corresponding to the closing price as of 5 February 2021. The reason for deviating from the shareholders' preferential rights in the Directed Issue is to strengthen the Company' institutional shareholder base and the proceeds will be used to accelerate the Company's existing business plan, mainly focusing on the development of MIV-818.

    Through the Directed Issue, the number of shares in Medivir will increase from 52,135,651 series B shares, including the shares issued in connection with the Rights Issue and the Over-allotment Option, to 55,735,651 series B shares, corresponding to a dilutive effect of approximately 6.5 per cent of the total number of outstanding shares and votes in the Company. Following the completion of the Directed Issue, LINC will hold shares in the Company corresponding to approximately 10 per cent of the total number of outstanding shares in the Company.

    Advisors

    ABG Sundal Collier is the financial advisor and Vinge is the legal advisor to Medivir in connection with the transaction.

    For additional information, please contact:

    Yilmaz Mahshid, CEO

    Telephone: +46 8 5468 3100

    E-mail:

    Magnus Christensen, CFO

    Telephone: +46 8 5468 3100

    E-mail:

    This information is information that Medivir AB (publ) is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact persons set out above, at 19.50 CET on 7 February 2021.

    Medivir in brief

    Medivir develops innovative drugs with a focus on cancer where the unmet medical needs are high. The drug candidates are directed toward indication areas where available therapies are limited or missing and there are great opportunities to offer significant improvements to patients. Medivir is focusing on the development of MIV-818, a pro-drug designed to selectively treat liver cancer cells and to minimize side effects. 

    Collaborations and partnerships are important parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences (NASDAQ:IGMS) to be developed in combination with IGM-antibodies for the treatment of solid tumors. Medivir's share (TICKER:MVIR) is listed on Nasdaq Stockholm's Small Cap list. www.medivir.com

    Important information

    Publication, release, or distribution of this press release may in certain jurisdictions be subject to legal restrictions and persons in the jurisdictions where the press release has been made public or distributed should be informed of and follow such legal restrictions. The recipient of this press release is responsible for using this press release and the information herein in accordance with applicable rules in each jurisdiction. This press release does not constitute an offer or solicitation to buy or subscribe for any securities in Medivir in any jurisdiction, either from Medivir or from anyone else.

    This press release is not a prospectus according to the definition in Regulation (EU) 2017/2019 ("the Prospectus Regulation") and has not been approved by any regulatory authority in any jurisdiction.

    This press release does not constitute an offer or solicitation to buy or subscribe for securities in the United States. The securities mentioned herein may not be sold in the United States without registration, or without an exemption from registration, under the U.S. Securities Act from 1933 ("Securities Act"), and may not be offered or sold within the United States without being registered, covered by an exemption from, or part of a transaction that is not subject to the registration requirements according to the Securities Act. There is no intention to register any securities mentioned herein in the United States or to issue a public offering of such securities in the United States. The information in this press release may not be released, published, copied, reproduced or distributed, directly or indirectly, wholly or in part, in or to Australia, Hong Kong, Japan, Canada, New Zealand, Singapore, South Africa, the United States or any other jurisdiction where the release, publication or distribution of this information would violate current rules or where such an action is subject to legal restrictions or would require additional registration or other measures beyond those that follow from Swedish law. Actions in contravention of this instruction may constitute a violation of applicable securities legislation.

    Forward- looking statements

    This press release contains forward-looking statements related to the Company's intentions, estimates or expectations with regard to the Company's future results, financial position, liquidity, development, outlook, estimated growth, strategies and opportunities as well as the markets in which the Company is active. Forward-looking statements are statements that do not refer to historical facts and can be identified by the use of terms such as "believes," "expects," "anticipates," "intends," "estimates," "will," "may," "implies," "should," "could" and, in each case, their negative, or comparable terminology. The forward-looking statements in this press release are based on various assumptions, which in several cases are based on further assumptions. Although the Company believes that the assumptions reflected in these forward-looking statements are reasonable, there is no guarantee that they will occur or that they are correct. Since these assumptions are based on assumptions or estimates and involve risks and uncertainties, actual results or outcomes, for many different reasons, may differ materially from those what is stated in the forward-looking statements. Due to such risks, uncertainties, eventualities and other significant factors, actual events may differ materially from the expectations that expressly or implicitly are contained in this press release through the forward-looking statements. The Company does not guarantee that the assumptions which serve as a basis for the forward-looking statements in this press release are correct, and each reader of the press release should not rely on the forward-looking statements in this press release. The information, opinions and forward-looking statements that expressly or implicitly are stated herein are provided only as of the date of this press release and may change. Neither the Company nor any other party will review, update, confirm or publicly announce any revision of any forward-looking statement to reflect events that occur or circumstances that arise with respect to the contents of this press release, beyond what is required by law or Nasdaq Stockholm's rules for issuers.

    Potential investors should not put undue trust in the forward-looking statements herein.

    This information was brought to you by Cision http://news.cision.com

    https://news.cision.com/medivir/r/medivir-proposes-directed-issue-of-approximately-sek-28-million-to-the-company-s-existing-specialist,c3281779

    The following files are available for download:

     

    Cision View original content:http://www.prnewswire.com/news-releases/medivir-proposes-directed-issue-of-approximately-sek-28-million-to-the-companys-existing-specialist-investor-linc-301223584.html

    SOURCE Medivir

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  5. MOUNTAIN VIEW, Calif., Feb. 05, 2021 (GLOBE NEWSWIRE) -- IGM Biosciences, Inc. (NASDAQ:IGMS), a clinical-stage biotechnology company focused on creating and developing engineered IgM antibodies, today announced that Fred Schwarzer, Chief Executive Officer, will participate in a fireside chat at the Guggenheim Healthcare Talks 2021 Idea Forum Oncology Day on February 12, 2021 at 2:00 p.m. ET. The conference will be held in a virtual meeting format.

    A live webcast of the event will be available on the "Events and Presentations" page in the "Investors" section of the Company's website at https://investor.igmbio.com/news-and-events/events-and-presentations. A replay of the webcast will be archived on the Company's website for 90 days following…

    MOUNTAIN VIEW, Calif., Feb. 05, 2021 (GLOBE NEWSWIRE) -- IGM Biosciences, Inc. (NASDAQ:IGMS), a clinical-stage biotechnology company focused on creating and developing engineered IgM antibodies, today announced that Fred Schwarzer, Chief Executive Officer, will participate in a fireside chat at the Guggenheim Healthcare Talks 2021 Idea Forum Oncology Day on February 12, 2021 at 2:00 p.m. ET. The conference will be held in a virtual meeting format.

    A live webcast of the event will be available on the "Events and Presentations" page in the "Investors" section of the Company's website at https://investor.igmbio.com/news-and-events/events-and-presentations. A replay of the webcast will be archived on the Company's website for 90 days following the presentation.

    About IGM Biosciences, Inc.

    Headquartered in Mountain View, California, IGM Biosciences is a clinical-stage biotechnology company focused on creating and developing engineered IgM antibodies. Since 2010, IGM Biosciences has worked to overcome the manufacturing and protein engineering hurdles that have limited the therapeutic use of IgM antibodies. Through its efforts, IGM Biosciences has created a proprietary IgM technology platform for the development of IgM antibodies for those clinical indications where their inherent properties may provide advantages as compared to IgG antibodies.

    Contact:

    Argot Partners

    David Pitts

    212-600-1902



    Primary Logo

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