ICVX Icosavax Inc.

25.42
-2.29  -8%
Previous Close 27.71
Open 27.7
52 Week Low 21.7
52 Week High 49.99
Market Cap $1,001,227,352
Shares 39,387,386
Float 24,561,435
Enterprise Value $1,105,314,402
Volume 65,186
Av. Daily Volume 264,137
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Upcoming Catalysts

Drug Stage Catalyst Date
IVX-A12
RSV/human Metapneumovirus (hMPV)
Phase 1
Phase 1
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IVX-121
Respiratory syncytial virus (RSV) vaccine
Phase 1
Phase 1
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IVX-411
COVID-19 vaccine
Phase 1/2
Phase 1/2
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Latest News

  1. - Initiated a Phase 1/2 clinical trial for IVX-411, a virus-like particle (VLP) displaying the SARS-CoV-2 receptor-binding domain -

    - Initiated a Phase 1/1b clinical trial for IVX-121, a VLP displaying a Respiratory Syncytial Virus (RSV) stabilized pre-fusion F antigen -

    - Raised $209.3 million in gross proceeds from an upsized IPO, funding operations through at least 2024 -

    SEATTLE, Sept. 13, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases, today reported financial results for the second quarter ended June 30…

    - Initiated a Phase 1/2 clinical trial for IVX-411, a virus-like particle (VLP) displaying the SARS-CoV-2 receptor-binding domain -

    - Initiated a Phase 1/1b clinical trial for IVX-121, a VLP displaying a Respiratory Syncytial Virus (RSV) stabilized pre-fusion F antigen -

    - Raised $209.3 million in gross proceeds from an upsized IPO, funding operations through at least 2024 -

    SEATTLE, Sept. 13, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases, today reported financial results for the second quarter ended June 30, 2021 and provided a corporate update.

    "The second quarter and recent period has been a transformational time for Icosavax thanks to our initiation of two clinical trials, one in RSV and one in SARS-CoV-2, as well as our successful initial public offering and listing on the Nasdaq stock exchange. I would like to thank the entire Icosavax team for their hard work during this period, and I believe our company is now well-positioned to further advance the development of our VLP vaccine pipeline," said Adam Simpson, Chief Executive Officer of Icosavax. "Our novel VLP platform has shown promise to drive a robust, broad, and durable protective immune response to complex antigens. To this end, we are delighted to have recently initiated the Phase 1/1b trial of our RSV VLP vaccine candidate, IVX-121, in addition to the Phase 1/2 trial of our COVID-19 VLP vaccine candidate, IVX-411, and we look forward to providing future updates on these and our other programs."

    Second Quarter 2021 and Subsequent Highlights

    • Initiated a Phase 1/1b clinical trial of IVX-121. In September, Icosavax initiated a Phase 1/1b clinical trial to assess the safety and immunogenicity of IVX-121, the company's VLP displaying an RSV stabilized pre-fusion F antigen, in healthy adults (Phase 1), including older adults (Phase 1b). Assuming favorable results from the IVX-121 Phase 1/1b clinical trial and favorable preclinical data from its human Metapneumovirus (hMPV) VLP candidate, Icosavax plans to thereafter initiate a Phase 1 clinical trial of its IVX-A12 bivalent RSV/hMPV vaccine candidate.



    • Completed successful IPO; listed on Nasdaq. In July, Icosavax successfully priced its initial public offering raising gross proceeds of $209.3 million prior to deducting underwriting fees, commissions and offering expenses, expected to enable the company to fund its operations through at least 2024. Icosavax's common stock began trading on the Nasdaq Global Select Market under the ticker symbol "ICVX" on July 29, 2021.



    • Initiated a Phase 1/2 clinical trial of IVX-411. In June, Icosavax initiated a Phase 1/2 clinical trial to assess the safety and immunogenicity of IVX-411, the company's VLP displaying the SARS-CoV-2 receptor-binding domain. Part 1 of this trial, in adults who have neither had COVID-19 nor been vaccinated with a licensed COVID-19 vaccine, has completed dosing, and Part 2 of this trial, in adults who have previously completed a vaccine regimen using a licensed COVID-19 vaccine, has now been initiated.



    • Appointed Elizabeth Bekiroglu as General Counsel. In September, Icosavax appointed Elizabeth Bekiroglu as the company's General Counsel. Ms. Bekiroglu has over 15 years of experience advising pharmaceutical and biotechnology companies on a broad range of legal matters. Ms. Bekiroglu most recently served as Associate General Counsel for Seagen, where she helped lead and build the legal affairs group as Seagen transformed into a multi-product, multinational company.



    • Appointed Thomas Russo as Chief Financial Officer. In June, Thomas Russo was appointed as Chief Financial Officer. Mr. Russo is a seasoned financial executive who joins the company with more than 25 years of diverse industry experience across finance, operations and sell-side equity research for public biotechnology companies. Prior to Icosavax, Mr. Russo most recently served as Chief Financial Officer of Assembly Biosciences, where he contributed to financings both through the capital markets and non-dilutive sources.



    • Appointed additional Board members. Icosavax appointed Heidi Kunz and Ann Veneman to the Board of Directors in May and July 2021, respectively. Ms. Kunz is a seasoned healthcare executive who sits on the Boards of several healthcare companies and most recently served as Executive Vice President and CFO of Blue Shield of California. Ms. Veneman has a distinguished career in public service, most recently serving as the Executive Director of the United Nations Children's Fund (UNICEF). Additionally, Mark McDade, who has served on Icosavax's Board of Directors since August 2019, was elected to chair the Board in August 2021 following the sudden passing of the company's co-founder and former Board Chair, Tadataka (Tachi) Yamada. Icosavax paid tribute to Tachi Yamada and his impact on public health during a Nasdaq closing bell ceremony in August 2021.



    • Completed successful Series B financing. In April, Icosavax announced closing of a $100 million Series B financing led by RA Capital Management and joined by Janus Henderson Investors, Perceptive Advisors, Viking Global Investors, Cormorant Asset Management, Omega Funds, and Surveyor Capital (a Citadel company) as well as existing investors. In conjunction with the financing, Peter Kolchinsky, Ph.D., founder and managing partner of RA Capital Management, joined the company's Board of Directors.

    Near-Term Milestone Expectations

    • Phase 1/2 interim/topline data for IVX-411, in 1H 2022



    • Phase 1/1b interim/topline data for IVX-121, in 1H 2022



    • IND submission for IVX-A12, a combination bivalent RSV/human Metapneumovirus (hMPV) VLP vaccine candidate, in 1H 2022

    Second Quarter 2021 Financial Results

    • Cash, cash equivalents and short-term investments as of June 30, 2021 were $111.8 million, compared to $15.5 million for the period ended December 31, 2020. Subsequently, in July, the company raised $190.6 million in net proceeds from its initial public offering. Icosavax currently expects its cash balance to be sufficient to fund operations through at least 2024. 



    • Research and development (R&D) expenses for the three months ended June 30, 2021 were $8.3 million, compared to $4.7 million for the same period in 2020. The increase was primarily driven by increased clinical development and manufacturing costs, growth in the number of R&D employees, non-clinical development and manufacturing activity, and stock-based compensation expense. Research and development expenses include non-cash stock-based compensation expense of $0.4 million for the three months ended June 30, 2021 versus an immaterial amount for the same period in 2020.



    • General and administrative expenses for the three months ended June 30, 2021 were $2.2 million, compared to $0.5 million for the same period in 2020. The increase was primarily due to increased stock-based compensation expense, growth in the number of G&A employees, and professional services including legal fees to support the company's growth. General and administrative expenses include non-cash stock-based compensation expenses of $0.9 million for the three months ended June 30, 2021 versus an immaterial amount for the same period in 2020.



    • Net loss for the three months ended June 30, 2021 was $8.6 million, or a basic and diluted net loss per share attributable to common stockholders of $2.86. Net loss for the same period in 2020 was $5.2 million, or basic and diluted net loss per share attributable to common stockholders of $2.45.

    About Icosavax's Virus-Like Particle (VLP) Vaccines

    VLPs enable multivalent display of antigens in a manner that closely resembles viruses but contain no genetic material. Approved vaccines that are derived from naturally occurring VLPs have shown efficacy when formulated as combination vaccines and have shown the ability to induce high and sustained levels (titers) of neutralizing antibodies (nAbs) in adults, which have generally been associated with protective immunity. However, VLPs engineered to display complex viral antigens have in general been difficult to develop or successfully manufacture at scale, limiting the pathogens that can be addressed by this approach. Icosavax's VLP vaccine technology is designed to enable robust, durable and broad immune responses against a broader array of pathogens than has been possible with naturally occurring VLPs and to overcome the manufacturing challenges experienced with other VLP technologies.

    About Icosavax

    Icosavax is a biopharmaceutical company leveraging its innovative VLP platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases. Icosavax's VLP platform technology is designed to enable multivalent, particle-based display of complex viral antigens, which it believes will induce broad, robust, and durable protection against the specific viruses targeted. Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Icosavax was formed in 2017 to advance the breakthrough VLP technology from the Institute for Protein Design at the University of Washington with the goal to discover, develop, and commercialize vaccines against infectious diseases. Icosavax exclusively licensed the VLP technology for use in several fields, including RSV and hMPV, from the University of Washington. For SARS-CoV-2, Icosavax has a non-exclusive, worldwide (excluding South Korea) license from the University of Washington that will convert to an exclusive license in North America and Europe in 2025. Icosavax is located in Seattle. 

    Forward-Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are forward-looking statements. The forward-looking statements are based on the company's current beliefs and expectations and include, but are not limited to: the company's expectation regarding the opportunities for, and the therapeutic and commercial potential of, its vaccine product candidates; the company's ability to advance its development program and achieve the noted development milestones in 2022; and the sufficiency of the company's current cash, cash equivalents, and investments to fund its operations through at least 2024. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in the company's business, including, without limitation: the early stage of the company's development efforts; the company's approach to the development of vaccine candidates, including its plan to pursue a combination bivalent RSV/hMPV VLP vaccine candidate, which is a novel and unproven approach; potential delays in the commencement, enrollment, and completion of clinical trials and preclinical studies; the company's dependence on third parties in connection with manufacturing, research, and preclinical and clinical testing; unexpected adverse side effects or inadequate efficacy of the company's product candidates that may limit their development, regulatory approval, and/or commercialization; results from preclinical studies or early clinical trials not necessarily being predictive of future results; competing approaches limiting the commercial value of the company's vaccine candidates; regulatory developments in the United States and other countries; the company's ability to obtain and maintain intellectual property protection for its product candidates and maintain its rights under intellectual property licenses; the company's ability to fund its operating plans with its current cash, cash equivalents, and investments; the company's ability to maintain undisrupted business operations during the COVID-19 pandemic, including with respect to clinical trials, manufacturing, and supply chain; and other risks described in the company's prior filings with the Securities and Exchange Commission (SEC), including under the heading "Risk Factors" in the company's Registration Statement on Form S-1 and any subsequent filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and the company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

    Media Contact:

    Jessica Yingling, Ph.D.,

    Little Dog Communications Inc.

    jessica@litldog.com

    858.344.8091

    Investor Contact:

    Laurence Watts

    Gilmartin Group, LLC

    laurence@gilmartinir.com

    619.916.7620



    ICOSAVAX, INC.

    Condensed Balance Sheets

    (in thousands, except share and par value data)

    (Unaudited)

      June 30,  December 31, 
      2021  2020 
    Assets      
    Current assets:      
    Cash $110,585  $13,114 
    Restricted cash  1,179   2,384 
    Prepaid expenses and other current assets  4,119   662 
    Total current assets  115,883   16,160 
    Property and equipment, net  561   10 
    Deferred offering costs  2,265    
    Total assets $118,709  $16,170 
    Liabilities, convertible preferred stock, and stockholders' deficit      
    Current liabilities:      
    Accounts payable $3,111  $1,918 
    Accrued and other current liabilities  1,825   1,532 
    Deferred revenue  1,179   2,384 
    Total current liabilities  6,115   5,834 
    Long-term convertible promissory note     4,947 
    Embedded derivative liability     1,604 
    Other noncurrent liabilities  279   426 
    Total liabilities  6,394   12,811 
    Convertible preferred stock, $0.0001 par value; 89,908,215 and 54,039,749 shares authorized at June 30, 2021 and December 31, 2020, respectively; 89,908,215 and 32,198,879 shares issued and outstanding at June 30, 2021 and December 31, 2020, respectively 151,613   30,062 
    Total stockholders' deficit  (39,298)  (26,703)
    Total liabilities, convertible preferred stock and stockholders' deficit $118,709  $16,170 
             

    ICOSAVAX, INC.

    Condensed Statements of Operations and Comprehensive Loss

    (Unaudited)

    (in thousands, except share and per share data)

      Three Months Ended

    June 30,
      Six Months Ended

    June 30,
     
      2021  2020  2021  2020 
    Grant revenue $1,904  $  $3,905  $ 
    Operating expenses:            
    Research and development  8,277   4,666   13,830   7,586 
    General and administrative  2,221   541   3,312   1,153 
    Total operating expenses  10,498   5,207   17,142   8,739 
    Loss from operations  (8,594)  (5,207)  (13,237)  (8,739)
    Other income (expense):            
    Change in fair value of embedded derivative liability        (205)   
    Loss on extinguishment of convertible promissory note        (754)   
    Interest and other income (expense)  42   9   (207)  70 
    Total other income (expense)  42   9   (1,166)  70 
    Net loss and comprehensive loss $(8,552) $(5,198) $(14,403) $(8,669)
    Net loss per share, basic and diluted $(2.86) $(2.45) $(5.00) $(4.23)
    Weighted-average common shares outstanding, basic and diluted  2,985,183   2,119,312   2,878,163   2,047,803 


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  2. SEATTLE, Sept. 10, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, today announced the appointment of Elizabeth Bekiroğlu to General Counsel.

    "Elizabeth is an accomplished leader who has established an expertise in providing legal counsel to biotechnology and healthcare companies," said Adam Simpson, Chief Executive Officer of Icosavax. "I am thrilled to begin working alongside Elizabeth and look forward to her valuable insight as we work to progress our clinical candidates down the development pipeline and continue to grow the company."

    Ms. Bekiroğlu brings more than 15 years of…

    SEATTLE, Sept. 10, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, today announced the appointment of Elizabeth Bekiroğlu to General Counsel.

    "Elizabeth is an accomplished leader who has established an expertise in providing legal counsel to biotechnology and healthcare companies," said Adam Simpson, Chief Executive Officer of Icosavax. "I am thrilled to begin working alongside Elizabeth and look forward to her valuable insight as we work to progress our clinical candidates down the development pipeline and continue to grow the company."

    Ms. Bekiroğlu brings more than 15 years of experience advising pharmaceutical and biotechnology companies on a broad range of legal matters. Prior to joining Icosavax, Ms. Bekiroğlu was Associate General Counsel at Seagen where she helped lead and build the legal affairs group as Seagen transformed into a multi-product, multinational company. Previously, she led the legal function at Oncothyreon where she handled a wide range of corporate, securities, clinical, manufacturing, licensing and transactional matters. Prior to Oncothyreon, Ms. Bekiroğlu served in roles of increasing responsibility at Emergent BioSolutions and Trubion Pharmaceuticals. Ms. Bekiroğlu began her legal career as a corporate associate at Fenwick & West LLP and Orrick, Herrington & Sutcliffe LLP where she advised early stage and public biopharmaceutical companies. Ms. Bekiroğlu received her J.D. from Harvard Law School and a B.A. in Human Biology from Stanford University.

    About Icosavax

    Icosavax is a biopharmaceutical company leveraging its innovative VLP platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases. Icosavax's VLP platform technology is designed to enable multivalent, particle-based display of complex viral antigens, which it believes will induce broad, robust, and durable protection against the specific viruses targeted. Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Icosavax was formed in 2017 to advance the breakthrough VLP technology from the Institute for Protein Design at the University of Washington with the goal to discover, develop, and commercialize vaccines against infectious diseases. Icosavax exclusively licensed the VLP technology for use in several fields, including RSV and hMPV, from the University of Washington. For SARS-CoV-2, Icosavax has a non-exclusive, worldwide (excluding South Korea) license from the University of Washington that will convert to an exclusive license in North America and Europe in 2025. Icosavax is located in Seattle.

    Forward Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are forward-looking statements. The forward-looking statements are based on our current beliefs and expectations and include, but are not limited to: our goal to progress our clinical candidates down the development pipeline and to continue to grow Icosavax, and the therapeutic potential of our VLP technology. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in our business, including, without limitation: the early stage of our development efforts; our approach to the discovery and development of vaccine candidates, which is a novel and unproven approach; potential delays in the commencement, enrollment, and completion of clinical trials; and other risks described in our prior filings with the Securities and Exchange Commission (SEC), including under the heading "Risk Factors" in our Registration Statement on Form S-1 and any subsequent filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and we undertake no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

    Media Contact: 

    Jessica Yingling, Ph.D.

    Little Dog Communications Inc.

    jessica@litldog.com

    +1.858.344.8091

    Investor Contact: 

    Laurence Watts

    Gilmartin Group, LLC

    laurence@gilmartinir.com

    +1.619.916.7620



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  3. SEATTLE, Sept. 09, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, today announced the initiation of a Phase 1/1b clinical trial of IVX-121, a VLP displaying a Respiratory Syncytial Virus (RSV) stabilized pre-fusion F antigen, in healthy adults and older adults. Assuming favorable results from the IVX-121 Phase 1/1b clinical trial and favorable preclinical data from its human Metapneumovirus (hMPV) VLP candidate, Icosavax plans to thereafter initiate a Phase 1 clinical trial of its IVX-A12 bivalent RSV/hMPV vaccine candidate. 

    "I am delighted with the clinical progress Icosavax has recently…

    SEATTLE, Sept. 09, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, today announced the initiation of a Phase 1/1b clinical trial of IVX-121, a VLP displaying a Respiratory Syncytial Virus (RSV) stabilized pre-fusion F antigen, in healthy adults and older adults. Assuming favorable results from the IVX-121 Phase 1/1b clinical trial and favorable preclinical data from its human Metapneumovirus (hMPV) VLP candidate, Icosavax plans to thereafter initiate a Phase 1 clinical trial of its IVX-A12 bivalent RSV/hMPV vaccine candidate. 

    "I am delighted with the clinical progress Icosavax has recently made. The initiation of our second clinical trial in just three months bears testament to the concerted effort our team exerted in the development and manufacturing of our vaccine candidates," said Adam Simpson, Chief Executive Officer of Icosavax. "As part of our core strategy, we plan to transition IVX-121, our RSV monovalent VLP candidate, into a combination vaccine with RSV and hMPV, IVX-A12. With the vision of creating combination VLP vaccines, we believe that developing a bivalent vaccine targeting two of the leading viral causes of pneumonia in older adults could represent a compelling offering for both providers and patients. Currently, neither RSV nor hMPV have approved vaccines; IVX-A12 has the potential to prevent disease caused by both viruses in a single shot."

    The Phase 1/1b clinical trial of IVX-121 is a randomized, observer-blind, placebo-controlled multi-center study designed to evaluate the safety and immunogenicity of three dose levels of non-adjuvanted and aluminum-adjuvanted IVX-121 in healthy adults, including older adults. The trial will inform the dose of IVX-121 to be evaluated in combination with the Icosavax hMPV VLP candidate IVX-241 for the anticipated Phase 1 clinical trial of the RSV/hMPV bivalent vaccine candidate IVX-A12.

    The Phase 1 part of the trial is expected to enroll up to 90 healthy adults in Belgium. The Phase 1b part of the trial is expected to enroll up to 217 healthy older adults. It is anticipated that a subset of the older adult subjects will be followed for 12 months after vaccination to assess durability of immune response to IVX-121.

    Following the completion of the Phase 1/1b clinical trial of IVX-121, Icosavax intends to shift its development of the VLP vaccine candidate for RSV to an RSV/hMPV bivalent combination vaccine strategy. The company plans to submit an investigational new drug application (IND) to the U.S. Food and Drug Administration (FDA) in the first half of 2022 and, thereafter, initiate a Phase 1 clinical trial of IVX-A12.

    About Virus-Like Particles (VLP) Vaccines

    VLPs enable multivalent display of antigens in a manner that closely resembles viruses but contain no genetic material. Approved vaccines that are derived from naturally occurring VLPs have shown efficacy when formulated as combination vaccines and have shown the ability to induce high and sustained levels (titers) of neutralizing antibodies (nAbs) in adults, which have generally been associated with protective immunity. However, VLPs engineered to display complex viral antigens have in general been difficult to develop or successfully manufacture at scale, limiting the pathogens that can be addressed by this approach. Icosavax's VLP vaccine technology is designed to enable robust, durable and broad immune responses against a broader array of pathogens than has been possible with naturally occurring VLPs and to overcome the manufacturing challenges experienced with other VLP technologies. 

    About IVX-121, RSV VLP Vaccine Candidate

    IVX-121 targets respiratory syncytial virus (RSV), a major cause of viral pneumonia for which no vaccine has been FDA approved. IVX-121 incorporates a stabilized pre-fusion F antigen licensed from NIAID/NIH that has been previously studied in healthy adults (DS-Cav1;  Lancet 2021). RSV F is known to undergo major structural changes that allow viral entry into the host cell, and during that process, critical protective epitopes are lost. Protein design methods have stabilized pre-fusion F, leading to improved neutralizing responses in humans.

    About Icosavax

    Icosavax is a biopharmaceutical company leveraging its innovative VLP platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases. Icosavax's VLP platform technology is designed to enable multivalent, particle-based display of complex viral antigens, which it believes will induce broad, robust, and durable protection against the specific viruses targeted. Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Icosavax was formed in 2017 to advance the breakthrough VLP technology from the Institute for Protein Design at the University of Washington with the goal to discover, develop, and commercialize vaccines against infectious diseases. Icosavax exclusively licensed the VLP technology for use in several fields, including RSV and hMPV, from the University of Washington. For SARS-CoV-2, Icosavax has a non-exclusive, worldwide (excluding South Korea) license from the University of Washington that will convert to an exclusive license in North America and Europe in 2025. Icosavax is located in Seattle.

    Forward Looking Statements

    Statements contained in this press release regarding matters that are not historical facts are forward-looking statements. The forward-looking statements are based on our current beliefs and expectations and include, but are not limited to: our expectations regarding the potential therapeutic benefits of our product candidates, including IVX-121 and IVX-A12, the expected timing to file an IND and initiate a clinical trial of IVX-A12 and the potential advantages of our VLP technology. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in our business, including, without limitation: the early stage of our development efforts; our VLP technology and our plan to pursue a combination bivalent RSV/hMPV VLP vaccine candidate, both of which are novel and unproven; potential delays in the commencement, enrollment, and completion of clinical trials and preclinical studies; our dependence on third parties in connection with manufacturing, research, and preclinical and clinical testing; unexpected adverse side effects or inadequate efficacy of our product candidates that may limit their development, regulatory approval, and/or commercialization; results from preclinical studies or early clinical trials not necessarily being predictive of future results and other risks described in our prior filings with the Securities and Exchange Commission (SEC), including under the heading "Risk Factors" in our Registration Statement on Form S-1 and any subsequent filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and we undertake no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

    Media Contact: 

    Jessica Yingling, Ph.D.

    Little Dog Communications Inc.

    jessica@litldog.com

    +1.858.344.8091

    Investor Contact: 

    Laurence Watts

    Gilmartin Group, LLC

    laurence@gilmartinir.com

    +1.619.916.7620



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  4. Adams Street Partners, a private markets investment firm with $45 billion in assets under management, announced today that within a 7-day period last week three companies within its Growth Equity portfolio launched initial public offerings (IPOs). This string of public offerings includes the IPOs of Couchbase (NYSE:BASE) on July 22, Icosavax (NYSE:ICVX) on July 28, and Robinhood (NYSE:HOOD) on July 29.

    "Congratulations to the teams at Robinhood, Couchbase, and Icosavax," said Jeff Diehl, Managing Partner and Head of Investments at Adams Street. "These high-profile public offerings reflect the vision and hard work of the respective companies' leaders and their teams. Adams Street's Growth Equity Team seeks to help innovative founders and business…

    Adams Street Partners, a private markets investment firm with $45 billion in assets under management, announced today that within a 7-day period last week three companies within its Growth Equity portfolio launched initial public offerings (IPOs). This string of public offerings includes the IPOs of Couchbase (NYSE:BASE) on July 22, Icosavax (NYSE:ICVX) on July 28, and Robinhood (NYSE:HOOD) on July 29.

    "Congratulations to the teams at Robinhood, Couchbase, and Icosavax," said Jeff Diehl, Managing Partner and Head of Investments at Adams Street. "These high-profile public offerings reflect the vision and hard work of the respective companies' leaders and their teams. Adams Street's Growth Equity Team seeks to help innovative founders and business leaders build great companies. Sectors like technology and healthcare continue to experience growth, dislocation and change and these forces can create meaningful opportunities for private markets investors."

    "Adams Street is a longtime growth capital investor and we strive to support our portfolio's CEOs and entrepreneurs with the full resources of our global platform and network of relationships," said Robin Murray, Partner and Head of Growth Equity Investments at Adams Street.

    Adams Street's Growth Equity Team is focused on helping and supporting innovative technology companies as those companies work to become market leaders. The Growth Equity Team's efforts leverage Adams Street's nearly five decades of experience and an extensive global platform with 10 offices around the world. Adams Street has tailored its portfolio support with a goal of offering highly impactful financial, operational, and talent services to CEOs and entrepreneurs.

    About Adams Street Partners

    Adams Street Partners is a global private markets investment manager with investments in more than thirty countries across five continents. The firm is 100% employee-owned and has $45 billion in assets under management. Adams Street strives to generate actionable investment insights across market cycles by drawing on nearly 50 years of private markets experience, proprietary intelligence, and trusted relationships. Adams Street has offices in Beijing, Boston, Chicago, London, Menlo Park, Munich, New York, Seoul, Singapore, and Tokyo. Visit www.adamsstreetpartners.com

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  5. SEATTLE, Aug. 05, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases, today acknowledged the sudden passing of Tadataka (Tachi) Yamada, M.D., co-founder and Chairman of the Board of Icosavax, who died unexpectedly on August 4, 2021.

    "It is with great sadness that we share the news of our Chairman and co-founder's sudden passing. Tachi was a brilliant man, a physician-scientist, and deeply committed to the cause of public health," said Adam Simpson, Chief Executive Officer of Icosavax, Inc. "I had the honor not just of co-founding…

    SEATTLE, Aug. 05, 2021 (GLOBE NEWSWIRE) -- Icosavax, Inc. (NASDAQ:ICVX), a biopharmaceutical company leveraging its innovative virus-like particle (VLP) platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases, today acknowledged the sudden passing of Tadataka (Tachi) Yamada, M.D., co-founder and Chairman of the Board of Icosavax, who died unexpectedly on August 4, 2021.

    "It is with great sadness that we share the news of our Chairman and co-founder's sudden passing. Tachi was a brilliant man, a physician-scientist, and deeply committed to the cause of public health," said Adam Simpson, Chief Executive Officer of Icosavax, Inc. "I had the honor not just of co-founding Icosavax with Tachi, but working with him previously. We look forward to continuing to advance Icosavax's vaccine candidates, to help make a profound impact on human health, as Tachi envisioned. On a personal level, I will miss his friendship, his optimism and his dedication, losses that I know are mitigated in some part by the enormous legacy he leaves behind. Needless to say, the Board, leadership, and employees of Icosavax offer their heartfelt condolences to Tachi's family and friends at this time."

    About Dr. Yamada

    Dr. Yamada had a prolonged and successful career in public health and the life sciences industry more broadly, having risen to lead R&D efforts for both Takeda and GlaxoSmithKline. He also was a former President of the Bill & Melinda Gates Foundation Global Health Program. Earlier in his career he was Chief of the Division of Gastroenterology and the Chair of the Department of Internal Medicine at the University of Michigan in Ann Arbor. In recognition of his contributions to medicine and science, he was elected to membership in the National Academy of Medicine (US), the Academy of Medical Sciences (UK) and the National Academy of Medicine (Mexico). Dr. Yamada served as chair of the board of directors at the Clinton Health Access Initiative and a member of the National Academy of Medicine in addition to chair of several biotech companies prior to his passing. 

    About Icosavax

    Icosavax is a biopharmaceutical company leveraging its innovative VLP platform technology to develop vaccines against infectious diseases, with an initial focus on life-threatening respiratory diseases. Icosavax's VLP platform technology is designed to enable multivalent, particle-based display of complex viral antigens, which it believes will induce broad, robust, and durable protection against the specific viruses targeted. Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Icosavax was formed in 2017 to advance the breakthrough VLP technology from the Institute for Protein Design at the University of Washington with the goal to discover, develop, and commercialize vaccines against infectious diseases. Icosavax exclusively licensed the VLP technology for use in several fields, including RSV and hMPV, from the University of Washington. For SARS-CoV-2, Icosavax has a non-exclusive, worldwide (excluding South Korea) license from the University of Washington that will convert to an exclusive license in North America and Europe in 2025. Icosavax is located in Seattle.

    Contact:

    For Media Only:

    Jessica Yingling, Ph.D.

    Little Dog Communications Inc.

    jessica@litldog.com

    +1.858.344.8091

    Icosavax Investor Contact:

    Laurence Watts

    Gilmartin Group, LLC

    laurence@gilmartinir.com

    +1.619.916.7620



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