HEPA Hepion Pharmaceuticals Inc.

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1. 18 February 2021 Hepion Pharmaceuticals, Inc. Announces Closing of Public Offering

   EDISON, NJ / ACCESSWIRE / February 18, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA), today announced the closing of its previously announced public offering of 44,200,000 shares of its common stock at a public offering price of $2.00 per share, for gross proceeds of $88,400,000, before deducting underwriting discounts and offering expenses. After deducting underwriting fees and other offering expenses payable by the Company, the net proceeds to the Company were approximately $82.1 million.

   The Company intends to use the net proceeds from the offering to fund research and development activities, as well as for working capital and other general corporate purposes.

   ThinkEquity, a division of Fordham Financial Management, Inc., acted as sole…

   EDISON, NJ / ACCESSWIRE / February 18, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA), today announced the closing of its previously announced public offering of 44,200,000 shares of its common stock at a public offering price of $2.00 per share, for gross proceeds of $88,400,000, before deducting underwriting discounts and offering expenses. After deducting underwriting fees and other offering expenses payable by the Company, the net proceeds to the Company were approximately $82.1 million.

   The Company intends to use the net proceeds from the offering to fund research and development activities, as well as for working capital and other general corporate purposes.

   ThinkEquity, a division of Fordham Financial Management, Inc., acted as sole book-running manager for the offering.

   A shelf registration statement on Form S-3 (File No. 333-229534), including a base prospectus, was filed with the U.S. Securities and Exchange Commission (the "SEC") on February 6, 2019 and declared effective on February 19, 2019. The offering was made by means of a written prospectus and prospectus supplement. The final prospectus supplement and accompanying prospectus related to the offering was filed with the SEC on February 16, 2021 and made available on the SEC's website at www.sec.gov. Copies of the final prospectus supplement and the accompanying prospectus relating to the offering may be obtained from ThinkEquity, a division of Fordham Financial Management, Inc., 17 State Street, 22nd Floor, New York, New York 10004, by telephone at (877) 436-3673, by email at .

   This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or other jurisdiction.

   About Hepion Pharmaceuticals, Inc.

   The Company's lead drug candidate, CRV431, is a potent inhibitor of cyclophilins, which are involved in many disease processes. CRV431 is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. CRV431 has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH; and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in preclinical studies.

   Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to CRV431, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing Phase 2a NASH program, Hepion will use the platform to identify additional potential indications for CRV431 to expand the company's footprint in the cyclophilin inhibition therapeutic space.

   Forward-Looking Statements

   Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as "anticipate," "believe," "forecast," "estimated," and "intend," among others. These forward-looking statements are based on Hepion Pharmaceuticals' current expectations and actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, that AI-POWR™ may fail to help us to discover and develop additional potential product candidates, substantial competition; our ability to continue as a going concern; our need for additional financing; uncertainties of patent protection and litigation; risks associated with delays, increased costs and funding shortages caused by the COVID-19 pandemic; uncertainties with respect to lengthy and expensive clinical trials, that results of earlier studies and trials may not be predictive of future trial results; uncertainties of government or third party payer reimbursement; limited sales and marketing efforts and dependence upon third parties; and risks related to failure to obtain FDA clearances or approvals and noncompliance with FDA regulations. As with any drug candidates under development, there are significant risks in the development, regulatory approval, and commercialization of new products. Hepion Pharmaceuticals does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk factors set forth in Hepion Pharmaceuticals' Form 10-K for the year ended December 31, 2019 and other periodic reports filed with the Securities and Exchange Commission as well as the Company's final prospectus supplement filed with the Securities and Exchange Commission on February 16, 2021.

   For Investor Relations Inquiries:

   Hepion Pharmaceuticals, Inc.	Stephen Kilmer
   732-902-4000	Hepion Pharmaceuticals Investor Relations
   	646-274-3580
   https://hepionpharma.com/

   SOURCE: Hepion Pharmaceuticals, Inc.

   
   
   View source version on accesswire.com:
   https://www.accesswire.com/630618/Hepion-Pharmaceuticals-Inc-Announces-Closing-of-Public-Offering
   
   

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2. 16 February 2021 Hepion Pharmaceuticals Announces Pricing of Public Offering

   EDISON, N.J., Feb. 16, 2021 (GLOBE NEWSWIRE) -- Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA), a clinical stage biopharmaceutical company focused on the development of therapeutic drugs for the treatment of liver disease arising from non-alcoholic steatohepatitis ("NASH"), today announced the pricing of its underwritten public offering of 44,200,000 shares of its common stock at a public offering price of $2.00 per share, for gross proceeds of $88.4 million before deducting underwriting discounts, commissions and other offering expenses. All of the shares of common stock are being offered by the Company.
   

   ThinkEquity, a division of Fordham Financial Management, Inc., is acting as sole book-running manager for the offering.

   The offering…

   EDISON, N.J., Feb. 16, 2021 (GLOBE NEWSWIRE) -- Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA), a clinical stage biopharmaceutical company focused on the development of therapeutic drugs for the treatment of liver disease arising from non-alcoholic steatohepatitis ("NASH"), today announced the pricing of its underwritten public offering of 44,200,000 shares of its common stock at a public offering price of $2.00 per share, for gross proceeds of $88.4 million before deducting underwriting discounts, commissions and other offering expenses. All of the shares of common stock are being offered by the Company.
   
   

   ThinkEquity, a division of Fordham Financial Management, Inc., is acting as sole book-running manager for the offering.

   The offering is expected to close on February 18, 2021, subject to satisfaction of customary closing conditions.

   Hepion intends to use the net proceeds from the offering to fund research and development activities, as well as for working capital and other general corporate purposes.

   A shelf registration statement on Form S-3 (File No. 333-229534), including a base prospectus, was filed with the U.S. Securities and Exchange Commission (the "SEC") on February 6, 2019 and declared effective on February 19, 2019. The offering is being made only by means of a written prospectus and prospectus supplement. A preliminary prospectus supplement and accompanying prospectus describing the terms of the proposed offering have been filed with the SEC and are available on the SEC's website at www.sec.gov. A final prospectus supplement and accompanying prospectus related to the offering will be filed with the SEC and made available on the SEC's website. Copies of the final prospectus supplement and the accompanying prospectus relating to the offering may also be obtained, when available, from the offices of ThinkEquity, a division of Fordham Financial Management, Inc., 17 State Street, 22nd Floor, New York, New York 10004, by telephone at (877) 436-3673 or by email at .

   This press release shall not constitute an offer to sell or a solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

   About Hepion Pharmaceuticals

   The Company's lead drug candidate, CRV431, is a potent inhibitor of cyclophilins, which are involved in many disease processes. CRV431 is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. CRV431 has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH; and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in preclinical studies. 

   Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to CRV431, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing Phase 2a NASH program, Hepion will use the platform to identify additional potential indications for CRV431 to expand the company's footprint in the cyclophilin inhibition therapeutic space. 

   Forward Looking Statements

   Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as "anticipate," "believe," "forecast," "estimated," and "intend," among others. These forward-looking statements are based on Hepion Pharmaceuticals' current expectations and include statements regarding the offering, the expected timing of the closing of the offering and the planned use of proceeds therefrom. Actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, the satisfaction of all conditions to, and the closing of, the offering. Hepion Pharmaceuticals does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk factors set forth in Hepion Pharmaceuticals' Form 10-K for the year ended December 31, 2019 and other periodic reports filed with the Securities and Exchange Commission.

   For further information, please contact:

   Stephen Kilmer
   
   Hepion Pharmaceuticals Investor Relations
   
   Direct: (646) 274-3580
   
   

   
   
   

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3. 12 February 2021 Hepion Pharmaceuticals, Inc. Announces Proposed Public Offering of Common Stock

   EDISON, NJ / ACCESSWIRE / February 12, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA) ("Hepion Pharmaceuticals" or the "Company") today announced that it intends to offer to sell shares of its common stock in an underwritten public offering. All of the shares of common stock are to be sold by the Company.

   ThinkEquity, a division of Fordham Financial Management, Inc., is acting as sole book-running manager for the offering.

   The offering is subject to market conditions and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

   The Company intends to use the net proceeds from the offering primarily for research and development, product development and general corporate purposes…

   EDISON, NJ / ACCESSWIRE / February 12, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA) ("Hepion Pharmaceuticals" or the "Company") today announced that it intends to offer to sell shares of its common stock in an underwritten public offering. All of the shares of common stock are to be sold by the Company.

   ThinkEquity, a division of Fordham Financial Management, Inc., is acting as sole book-running manager for the offering.

   The offering is subject to market conditions and there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.

   The Company intends to use the net proceeds from the offering primarily for research and development, product development and general corporate purposes, which may include working capital, capital expenditures, operational purposes and potential acquisitions in complementary businesses.

   The securities will be offered and sold pursuant to a shelf registration statement on Form S-3 (File No. 333-229534), including a base prospectus, filed with the U.S. Securities and Exchange Commission (the "SEC") on February 6, 2019 and declared effective on February 19, 2019. The offering will be made only by means of a written prospectus. A preliminary prospectus supplement and accompanying prospectus describing the terms of the offering has been or will be filed with the SEC on its website at www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus relating to the offering may also be obtained from the offices of ThinkEquity, a division of Fordham Financial Management, Inc., 17 State Street, 22nd Floor, New York, New York 10004, by telephone at (877) 436-3673 or by email at . Before investing in this offering, interested parties should read in their entirety the preliminary prospectus supplement and the accompanying prospectus and the other documents that the Company has filed with the SEC that are incorporated by reference in such preliminary prospectus supplement and the accompanying prospectus, which provide more information about the Company and such offering.

   This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of such state or jurisdiction.

   About Hepion Pharmaceuticals, Inc.
   The Company's lead drug candidate, CRV431, is a potent inhibitor of cyclophilins, which are involved in many disease processes. CRV431 is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. CRV431 has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH; and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in preclinical studies.

   Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to CRV431, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing Phase 2a NASH program, Hepion will use the platform to identify additional potential indications for CRV431 to expand the company's footprint in the cyclophilin inhibition therapeutic space.

   Forward-Looking Statements
   Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as "anticipate," "believe," "forecast," "estimated," and "intend," among others. These forward-looking statements are based on Hepion Pharmaceuticals' current expectations and include statements regarding the proposed offering, the expected timing of the closing of the offering and the planned use of proceeds therefrom. Actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, market conditions and the satisfaction of all conditions to, and the closing of, the offering. Hepion Pharmaceuticals does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk factors set forth in Hepion Pharmaceuticals' Form 10-K for the year ended December 31, 2019 and other periodic reports filed with the Securities and Exchange Commission.

   For Investor Relations Inquiries:
   Hepion Pharmaceuticals, Inc.
   732-902-4000
   
   https://hepionpharma.com/

   Stephen Kilmer
   Hepion Pharmaceuticals Investor Relations
   646-274-3580
   

   SOURCE: Hepion Pharmaceuticals, Inc.

   
   
   View source version on accesswire.com:
   https://www.accesswire.com/629557/Hepion-Pharmaceuticals-Inc-Announces-Proposed-Public-Offering-of-Common-Stock
   
   

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4. 10 February 2021 Former Novo Nordisk Executive, Dr. Todd M. Hobbs, Joins Hepion Pharmaceuticals as Chief Medical Officer

   EDISON, NJ / ACCESSWIRE / February 10, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA)("Hepion"), a clinical stage biopharmaceutical company focused on Artificial Intelligence ("AI")-driven therapeutic drug development for the treatment of non-alcoholic steatohepatitis ("NASH") and liver disease, today announced the appointment of Todd M. Hobbs, M.D., to the newly created position of Chief Medical Officer ("CMO"), effective February 16, 2021.

   In this role, Dr. Hobbs will help lead Hepion's engagement with the U.S. Food and Drug Administration ("FDA"), global and national thought leaders, key policymakers, and professional associations.

   Dr. Hobbs joins Hepion from Novo Nordisk Inc., one of the world's leading healthcare companies. His 16 years…

   EDISON, NJ / ACCESSWIRE / February 10, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA)("Hepion"), a clinical stage biopharmaceutical company focused on Artificial Intelligence ("AI")-driven therapeutic drug development for the treatment of non-alcoholic steatohepatitis ("NASH") and liver disease, today announced the appointment of Todd M. Hobbs, M.D., to the newly created position of Chief Medical Officer ("CMO"), effective February 16, 2021.

   In this role, Dr. Hobbs will help lead Hepion's engagement with the U.S. Food and Drug Administration ("FDA"), global and national thought leaders, key policymakers, and professional associations.

   Dr. Hobbs joins Hepion from Novo Nordisk Inc., one of the world's leading healthcare companies. His 16 years of progressive experience at Novo Nordisk includes positions ranging from field medical affairs leadership at the start of his corporate career through to his most recent role as North American Chief Medical Officer and Vice President. Prior to working at Novo Nordisk, Dr. Hobbs had established a clinical practice based in Louisville, Kentucky, focusing on the intensive management of patients with diabetes of all ages, and served as chairman of the medicine department for a large regional medical center in Kentucky. During his 10-year clinical career, he cared for more than 2,500 adults and children with diabetes, including outpatient and inpatient care, as well as intensive care.

   Dr. Hobbs currently serves as a Member of the Board for the American Medical Group Association Foundation, the research foundation arm of the American Medical Group Association, in which he provides oversight for multiple clinical research initiatives. Dr. Hobbs earned his medical degree from the University of Louisville School of Medicine and has completed focused executive training at the University of Pennsylvania's Wharton School of Business.

   "In addition to being a skilled physician, Todd is well recognized for his ability to lead collaboration on clinical development, regulatory strategy and medical affairs, as well as for his passionate commitment to ensuring clinical programs are designed to meet the needs of both clinicians and patients," commented Dr. Robert Foster, Hepion's CEO. "This, combined with his involvement in numerous successful commercial product launches, gives me great confidence that Todd will play a key role in the continued advancement of CRV431's clinical development."

   Dr. Hobbs said, "While the strong scientific foundation of cyclophilin-based drug discovery and development has taken decades for Hepion's senior management team and other researchers to build, it has been captivating to watch how quickly CRV431 has emerged as a leading therapeutic drug candidate for the treatment of NASH and other liver diseases. I am thrilled to be joining Hepion at this important time, and look forward to contributing to its success."

   About Hepion Pharmaceuticals

   The Company's lead drug candidate, CRV431, is a potent inhibitor of cyclophilins, which are involved in many disease processes. CRV431 is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. CRV431 has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH; and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in preclinical studies.

   Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to CRV431, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing Phase 2a NASH program, Hepion will use the platform to identify additional potential indications for CRV431 to expand the company's footprint in the cyclophilin inhibition therapeutic space.

   Forward-Looking Statements

   Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking words such as "anticipate," "believe," "forecast," "estimated," and "intend," among others. These forward-looking statements are based on Hepion Pharmaceuticals' current expectations and actual results could differ materially. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. These factors include, but are not limited to, the contribution of Dr. Hobbs; substantial competition; our ability to continue as a going concern; our need for additional financing; uncertainties of patent protection and litigation; risks associated with delays, increased costs and funding shortages caused by the COVID-19 pandemic; uncertainties with respect to lengthy and expensive clinical trials, that results of earlier studies and trials may not be predictive of future trial results; uncertainties of government or third party payer reimbursement; limited sales and marketing efforts and dependence upon third parties; and risks related to failure to obtain FDA clearances or approvals and noncompliance with FDA regulations. As with any drug candidates under development, there are significant risks in the development, regulatory approval, and commercialization of new products. There are no guarantees that future clinical trials discussed in this press release will be completed or successful, or that any product will receive regulatory approval for any indication or prove to be commercially successful. Hepion Pharmaceuticals does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk factors set forth in Hepion Pharmaceuticals' Form 10-K for the year ended December 31, 2019 and other periodic reports filed with the Securities and Exchange Commission.

   For further information, please contact:

   Stephen Kilmer
   Hepion Pharmaceuticals Investor Relations
   Direct: (646) 274-3580
   

   SOURCE: Hepion Pharmaceuticals, Inc.

   
   
   View source version on accesswire.com:
   https://www.accesswire.com/628859/Former-Novo-Nordisk-Executive-Dr-Todd-M-Hobbs-Joins-Hepion-Pharmaceuticals-as-Chief-Medical-Officer
   
   

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5. 09 February 2021 Hepion Pharmaceuticals to Participate in BIO CEO & Investor Digital Conference

   EDISON, NJ / ACCESSWIRE / February 9, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA)("Hepion"), a clinical stage biopharmaceutical company focused on Artificial Intelligence ("AI")-driven therapeutic drug development for the treatment of non-alcoholic steatohepatitis ("NASH") and liver disease, announced today that management will participate in the BIO CEO & Investor Digital Conference, which is being held February 16 - 18, 2021.

   Hepion's pre-recorded presentation will be available on demand during the virtual event for all registered attendees. Beginning on Tuesday, February 16, 2021, the presentation will also be available for approximately 30 days on the Company's website at www.hepionpharma.com under "Events" in the Investors section…

   EDISON, NJ / ACCESSWIRE / February 9, 2021 / Hepion Pharmaceuticals, Inc. (NASDAQ:HEPA)("Hepion"), a clinical stage biopharmaceutical company focused on Artificial Intelligence ("AI")-driven therapeutic drug development for the treatment of non-alcoholic steatohepatitis ("NASH") and liver disease, announced today that management will participate in the BIO CEO & Investor Digital Conference, which is being held February 16 - 18, 2021.

   Hepion's pre-recorded presentation will be available on demand during the virtual event for all registered attendees. Beginning on Tuesday, February 16, 2021, the presentation will also be available for approximately 30 days on the Company's website at www.hepionpharma.com under "Events" in the Investors section.

   About Hepion Pharmaceuticals
   The Company's lead drug candidate, CRV431, is a potent inhibitor of cyclophilins, which are involved in many disease processes. CRV431 is currently in clinical-phase development for the treatment of NASH, with the potential to play an important role in the overall treatment of liver disease - from triggering events through to end-stage disease. CRV431 has been shown to reduce liver fibrosis and hepatocellular carcinoma tumor burden in experimental models of NASH; and has demonstrated antiviral activities towards HBV, HCV, and HDV through several mechanisms, in preclinical studies.

   Hepion has created a proprietary AI platform, called AI-POWR™, which stands for Artificial Intelligence - Precision Medicine; Omics (including genomics, proteomics, metabolomics, transcriptomics, and lipidomics); World database access; and Response and clinical outcomes. Hepion intends to use AI-POWR™ to help identify which NASH patients will best respond to CRV431, potentially shortening development timelines and increasing the delta between placebo and treatment groups. In addition to using AI-POWR™ to drive its ongoing Phase 2a NASH program, Hepion will use the platform to identify additional potential indications for CRV431 to expand the company's footprint in the cyclophilin inhibition therapeutic space.

   For further information, please contact:
   Stephen Kilmer
   Hepion Pharmaceuticals Investor Relations
   Direct: (646) 274-3580
   

   SOURCE: Hepion Pharmaceuticals, Inc.

   
   
   View source version on accesswire.com:
   https://www.accesswire.com/628815/Hepion-Pharmaceuticals-to-Participate-in-BIO-CEO-Investor-Digital-Conference
   
   

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