COCP Cocrystal Pharma Inc.

1.53
+0.06  (+4%)
Previous Close 1.47
Open 1.45
52 Week Low 0.3861
52 Week High 2.95
Market Cap $79,775,269
Shares 52,140,699
Float 36,789,935
Enterprise Value $55,677,827
Volume 3,320,665
Av. Daily Volume 3,509,663
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Drug Pipeline

Drug Stage Notes
CC-42344
Influenza
Phase 1
Phase 1
Phase 1 trial to be initiated 2021.
CC-31244
Hepatitis C
Phase 2a
Phase 2a
Phase 2a updated data presented AASLD November 10, 2019.

Latest News

  1. - Company has sufficient capital to advance pipeline and fund operations through 2021 -

    BOTHELL, WA, May 14, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, today announced its financial results for the quarter ended March 31, 2020 and provided program updates.

    Recent Highlights

    • Entered into license agreement with Kansas State University Research Foundation ("KSURF") to further develop certain proprietary broad-spectrum antiviral compounds for the treatment of norovirus and coronavirus infections ("COVID-19").
    • Entered into additional license agreement with KSURF to include rights to additional preclinical…

    - Company has sufficient capital to advance pipeline and fund operations through 2021 -

    BOTHELL, WA, May 14, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, today announced its financial results for the quarter ended March 31, 2020 and provided program updates.

    Recent Highlights

    • Entered into license agreement with Kansas State University Research Foundation ("KSURF") to further develop certain proprietary broad-spectrum antiviral compounds for the treatment of norovirus and coronavirus infections ("COVID-19").
    • Entered into additional license agreement with KSURF to include rights to additional preclinical leads and further develop certain proprietary broad-spectrum antiviral compounds for the treatment of coronavirus infections.
    • Appointed Nobel Laureate and Scientific Advisor, Roger D. Kornberg, Ph.D., to its Board of Directors.
    • Completed the final report of U.S. Phase 2a clinical trial evaluating CC-31244 combination therapy for the ultrashort combination treatment of individuals infected with hepatitis C virus ("HCV"), confirming the previously released data that it is effective and well tolerated.
    • Completed three registered direct offerings since January 31, 2020 for combined total gross proceeds of $20 million, before deducting placement agent fees and offering expenses.
    • The Company's Bothell, WA research lab remains open for essential operations as it continues to work while meeting COVID-19 quarantine challenges.

    "We are pleased with the progress we have made over the course of the first quarter, despite the challenges due to the COVID-19 pandemic. The fundamentals of Cocrystal have never been stronger. Importantly, the Company has a strong cash position, with capital that we expect will be sufficient to fund our operations through 2021. Our pipeline of novel antivirals in development includes treatments for two of the most prevalent viruses affecting the globe: COVID-19 and influenza. By leveraging our novel platform technology, we believe Cocrystal is well positioned to continue addressing the shortcomings in the treatment of viruses with significant unmet needs, as well as develop safe and effective antiviral therapies for new or resistant viruses as they arise," commented Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal.

    Development Programs Overview

    Influenza A/B Inhibitors: Merck Collaboration
    Exclusive license and collaboration agreement with Merck to discover and develop certain proprietary influenza A/B antiviral agents.

    Cocrystal's exclusive license and collaboration agreement with Merck Sharp & Dohme Corp. ("Merck") to discover and develop certain proprietary influenza A/B antiviral agents remains ongoing. Cocrystal has been working with the scientific leadership at Merck over the past year in advancing the joint influenza A/B program. Merck, a global healthcare company with a history of over 125-years of drug discovery and innovation, has funded the collaborative influenza A/B program and could potentially provide up to $156 million in milestone payments as the collaboration proceeds through clinical and commercial development. The research and collaboration agreement with Merck also provides for royalties following commercialization.

    CC-42344: Influenza A Program:

    Novel, broad spectrum influenza antivirals that are specifically designed to be effective against all significant A strains of the influenza virus and to have a high barrier to resistance due to the way they target the virus' replication machinery.

    The Company's lead molecule in development, CC-42344, is currently being evaluated in preclinical IND-enabling studies for the treatment of influenza. CC-42344 has shown excellent antiviral activity against influenza A strains, including avian pandemic strains and Tamiflu® resistant strains, and shows a favorable pharmacokinetic and safety profile.

    Cocrystal is currently working to secure its supply chain and initiate its second lot of API synthesis for its influenza A program in Q3 2020. Subject to any additional delays due to the evolving COVID-19 pandemic, Cocrystal expects to file its regulatory submission and commence its Phase 1a study in 2021.

    COVID-19 Coronavirus Program:
    Aggressively pursuing the development of novel antiviral compounds for the treatment of coronavirus infections using our established proprietary drug discovery platform.

    The Company is currently advancing its Coronavirus program by leveraging the rights to preclinical leads from its license agreements with KSURF to further develop certain proprietary broad-spectrum antiviral compounds for the treatment of coronavirus (COVID-19) infections. The additional compounds licensed from KSURF have demonstrated both in vitro and in vivo activity in animal models against the viral pathogens causing MERS and SARS, coronaviruses that are structurally similar to SARS-CoV-2, which is responsible for the COVID-19 pandemic.

    Cocrystal initiated its preclinical studies of COVID-19 inhibitors received from KSURF during Q2 2020, and further intends to identify additional COVID-19 inhibitors from KSURF utilizing its proprietary platform technology over the course of the second and third quarter of this year. The Company also plans to identify additional inhibitors from internal sources using its proprietary platform technology in Q3 2020 and anticipates the selection of its lead preclinical molecule in Q4 2020.

    CC-31244: Hepatitis C Program:
    Potential best-in-class pan-genotypic inhibitor of NS5B polymerase for the ultra-short combination treatment of hepatitis C infection.

    The final study report of Cocrystal's U.S. Phase 2a clinical trial evaluating CC-31244 combination therapy for the ultrashort treatment of hepatitis C virus ("HCV") infected individuals has been completed and confirms the previously released data that it is effective and well tolerated. Partnering efforts are currently underway for the Company's fully owned ultrashort treatment of HCV.

    Norovirus Program:
    Developing inhibitors of the RNA-dependent RNA polymerase of norovirus.

    Cocrystal continues to identify and develop non-nucleoside polymerase inhibitors using its proprietary structure-based drug design technology platform. Cocrystal recently entered into license agreements with KSURF to further develop certain proprietary broad-spectrum antiviral compounds for humans to treat Norovirus and Coronavirus infections. Preclinical activities for Cocrystal's Norovirus program are currently underway. The Company expects to complete its proof-of-concept animal model study in Q4 2020.

    Summary of Financial Results for Q1 2020

    As of March 31, 2020, Cocrystal had approximately $21,686,000 cash on hand. Based on management's current projections, the Company believes it has sufficient capital to continue operations through 2021.

    For the quarter ended March 31, 2020, the Company had revenues of approximately $461,000 compared to $5,078,000 in revenue in the first quarter of 2019. The revenue for the three months ended March 31, 2019 included $4,368,000 as consideration in exchange for conveyance of intellectual property rights at the signing of the Merck Collaboration Agreement executed on January 2, 2019.

    For the quarter ended March 31, 2020, the Company reported net loss of approximately $1,990,000 compared to a net income of approximately $2,971,000 for the same period in 2019, primarily due to Merck revenue as explained above.

    Total research and development expenses were approximately $1,283,000 for the three months ended March 31, 2020, compared with $878,000 for the three months ended March 31, 2019. The increase was primarily due to increases in COVID-19 and Influenza programs. General and administrative expenses were $1,139,000 for the three months ended March 31, 2020, compared with $1,323,000 for the three months ended March 31, 2019.

    During the first quarter 2020, the Company closed the following offerings of its common stock to certain institutional investors:

    • January 29, 2020: Registered direct offering of 3,492,063 shares of common stock at a purchase price per share of $0.63 for aggregate gross proceeds to the Company of approximately $2.2 million, before deducting fees payable to the placement agent and other estimated offering expenses payable by the Company. The Company closed the offering on January 31, 2020.
       
    • February 27, 2020: Registered direct offering of 8,461,540 shares of common stock at a purchase price per share of $1.30 for aggregate gross proceeds to the Company of approximately $11.0 million, before deducting fees payable to the placement agent and other offering expenses payable by the Company. The Company closed the offering on February 28, 2020.
       
    • March 9, 2020: Registered direct offering of 5,037,038 shares of common stock at a purchase price per share of $1.35 for aggregate gross proceeds to the Company of approximately $6.8 million, before deducting fees payable to the placement agent and other offering expenses payable by the Company. The Company closed the offering on March 10, 2020.

    About Cocrystal Pharma, Inc.

    Cocrystal Pharma, Inc. is a clinical stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza viruses, hepatitis C viruses, coronaviruses and noroviruses. Cocrystal employs unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. For further information about Cocrystal, please visit www.cocrystalpharma.com.

    Cautionary Note Regarding Forward-Looking Statements

    This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements related to expected results of our collaboration with Merck, including the potential future milestone payments of up to $156,000,000 and royalties in connection with the collaboration; the anticipated timing of achieving the value-driving milestones in our influenza A program, including securing a supply chain and initiating the 2nd lot API synthesis in Q3 2020, filing the regulatory submission and commencing the Phase 1a study in 2021; the anticipated timing of achieving the value-driving milestones in our COVID-19 program, including identifying additional COVID-19 inhibitors using the Company's proprietary platform technology in Q2 and Q3 2020, and the selection of a preclinical lead molecule in Q4 2020; the anticipated timing of achieving the value-driving milestones in our norovirus program, including completion of a proof-of-concept animal study in Q4 2020; and our expectations regarding future liquidity. The words "believe," "proceeds," "may," "estimate," "continue," "anticipate," "intend," "should," "plan," "could," "target," "potential," "is likely," "will," "expect" and similar expressions, as they relate to us, are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events. Some or all of the events anticipated by these forward-looking statements may not occur. Important factors that could cause actual results to differ from those in the forward-looking statements include, but are not limited to, the risks arising from the impact of the COVID-19 pandemic on our Company, including (i) supply chain disruptions, (ii) our continued ability to proceed with our programs, and (iii) on the national and global economy, our reliance on certain third parties, our reliance on continuing collaboration with Merck under the collaboration agreement, the future results of preclinical and clinical studies, general risks arising from clinical trials, receipt of regulatory approvals, development of effective treatments and/or vaccines by competitors, any unanticipated litigation and other expenses and factors that affect the capital markets in general and early stage biotechnology companies specifically. Further information on our risk factors is contained in our filings with the SEC, including our Annual Report on Form 10-K for the year ended December 31, 2019. Any forward-looking statement made by us herein speaks only as of the date on which it is made. Additional factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. We undertake no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by law.

    Investor and Media Contact:
    JTC Team, LLC
    (833) 475-8247

    ###

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  2. – Company reprioritizes activities to accelerate development and provides next steps for advancing preclinical COVID-19 Coronavirus program –

    – Discussions ongoing with potential strategic partners for COVID-19 Coronavirus program –

    – Collaboration with Merck to discover and develop certain proprietary influenza A/B antiviral agents remains ongoing –

    – Supply chain delay in fully owned influenza A virus program –

    – Norovirus program on track to complete proof-of-concept animal study model in Q4 2020 –

    BOTHELL, WA, May 11, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, today provided an update on the…

    – Company reprioritizes activities to accelerate development and provides next steps for advancing preclinical COVID-19 Coronavirus program –

    – Discussions ongoing with potential strategic partners for COVID-19 Coronavirus program –

    – Collaboration with Merck to discover and develop certain proprietary influenza A/B antiviral agents remains ongoing –

    – Supply chain delay in fully owned influenza A virus program –

    – Norovirus program on track to complete proof-of-concept animal study model in Q4 2020 –

    BOTHELL, WA, May 11, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, today provided an update on the impact of the COVID-19 global pandemic on its preclinical and clinical development programs.

    "We have reprioritized development activities to accelerate the advancement of our preclinical COVID-19 program, which we recently established as a result of our license agreements with Kansas State University Research Foundation (KSRF)," commented Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal. "Like many of our peers, we have been working to minimize the impact of the COVID-19 pandemic on our operations. While we have been able to mitigate some of the risks, the worldwide impact on supply chains has resulted in a delay to our fully owned influenza A virus program. The full impact of COVID-19 on our development programs remains uncertain, but our team is determined to advance preclinical and clinical development programs across our pipeline as quickly and efficiently as possible."

    Programs Update

    Influenza A/B Inhibitors: Merck Collaboration

    Cocrystal's exclusive license and collaboration agreement with Merck to discover and develop certain proprietary influenza A/B antiviral agents remains ongoing. Cocrystal has been working with the scientific leadership at Merck over the past year in advancing the joint influenza A/B program. Merck, a global healthcare company with a history of over 125-years of drug discovery and innovation, has funded the collaborative influenza A/B program and could provide up to $156 million in milestones payments as the collaboration proceeds through clinical and commercial development. The research and collaboration agreement with Merck also provides for royalties following commercialization.

    CC-42344: Influenza A Program

    The Company's lead molecule in development, CC-42344, is currently being evaluated in preclinical IND-enabling studies for the treatment of influenza. CC-42344 has shown excellent antiviral activity against influenza A strains, including avian pandemic strains and Tamiflu® resistant strains, and shows a favorable pharmacokinetic and safety profile.

    Cocrystal is currently working to secure its supply chain and initiate its second lot of API synthesis for its influenza A program in Q3 2020. Subject to any additional delays due to the evolving COVID-19 pandemic, Cocrystal expects to file its regulatory submission and commence its Phase 1a study in 2021.

    COVID-19 Coronavirus Program

    The Company is currently advancing its Coronavirus program by leveraging the rights to preclinical leads from its license agreements with KSURF to further develop certain proprietary broad-spectrum antiviral compounds for the treatment of coronavirus (COVID-19) infections. The additional compounds licensed from KSURF have demonstrated both in vitro and in vivo activity in animal models against the viral pathogens causing MERS and SARS, coronaviruses that are structurally similar to SARS-CoV-2, which is responsible for the COVID-19 pandemic.

    Cocrystal initiated its preclinical studies of COVID-19 inhibitors received from KSURF during Q2 2020, and further intends to identify additional COVID-19 inhibitors utilizing its proprietary platform technology over the course of the second and third quarter of this year. The Company plans to identify additional inhibitors using its proprietary platform technology in Q3 2020 and anticipates the selection of its lead preclinical molecule in Q4 2020.

    CC-31244: Hepatitis C Program

    The final study report of Cocrystal's U.S. Phase 2a clinical trial evaluating CC-31244 combination therapy for the ultrashort treatment of hepatitis C virus ("HCV") infected individuals has been completed and confirms the previously released data that it is effective and well tolerated. Partnering efforts are currently underway for the Company's fully owned ultrashort treatment of HCV.

    Norovirus Program

    Cocrystal continues to identify and develop non-nucleoside polymerase inhibitors using its proprietary structure-based drug design technology platform. Cocrystal recently entered into a license agreement with KSURF to further develop certain proprietary broad-spectrum antiviral compounds for humans to treat Norovirus and Coronavirus infections. Preclinical activities for Cocrystal's Norovirus program are currently underway. The Company expects to complete its proof-of-concept animal model study in Q4 2020.

    About Cocrystal Pharma, Inc.

    Cocrystal Pharma, Inc. is a clinical stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza viruses, hepatitis C viruses, coronaviruses and noroviruses. Cocrystal employs unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. For further information about Cocrystal, please visit www.cocrystalpharma.com.

    Cautionary Note Regarding Forward-Looking Statements

    This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements that we could receive milestone and royalty payments under the research and collaboration agreement with Merck; the expected timing of initiation of the second lot of API and the filing of the regulatory submission and commencement of the Phase 1a study for the influenza A program; the anticipated timing of identification of additional COVID-19 inhibitors and selection of its lead preclinical molecule in the Coronavirus program; our expected progress in partnering discussions regarding the ultrashort treatment of HCV, and the expected progress of the Norovirus program, including the completion of proof-of-concept animal model study. The words "believe," "proceeds," "may," "estimate," "continue," "anticipate," "intend," "should," "plan," "could," "target," "potential," "is likely," "will," "expect" and similar expressions, as they relate to us, are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events. Some or all of the events anticipated by these forward-looking statements may not occur. Important factors that could cause actual results to differ from those in the forward-looking statements include, but are not limited to, risks arising from the impact of the COVID-19 pandemic on our Company, including our ability to proceed with our programs, receive necessary regulatory approvals and continue to rely on certain third parties, and on the national and global economy, the results of preclinical and clinical studies, general risks arising from clinical trials, receipt of regulatory approvals, development of effective treatments and/or vaccines by competitors, and our ability to find and enter into agreements with suitable collaboration partners. Further information on our risk factors is contained in our filings with the SEC, including our Annual Report on Form 10-K for the year ended December 31, 2019. Any forward-looking statement made by us herein speaks only as of the date on which it is made. Factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. We undertake no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by law.

    Investor and Media Contact:
    JTC Team, LLC
    (833) 475-8247

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  3. - Expanded license agreement with KSURF further broadens and advances Cocrystal's COVID-19 program -

    - Small molecule therapeutic inhibitors against coronaviruses included in agreement have demonstrated strong proof-of-concept and excellent efficacy data in MERS-CoV animal models -

    BOTHELL, WA, April 22, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today that it has expanded its previously announced license agreement with Kansas State University Research Foundation ("KSURF") to include rights to additional preclinical leads and further develop certain proprietary broad-spectrum antiviral…

    - Expanded license agreement with KSURF further broadens and advances Cocrystal's COVID-19 program -

    - Small molecule therapeutic inhibitors against coronaviruses included in agreement have demonstrated strong proof-of-concept and excellent efficacy data in MERS-CoV animal models -

    BOTHELL, WA, April 22, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today that it has expanded its previously announced license agreement with Kansas State University Research Foundation ("KSURF") to include rights to additional preclinical leads and further develop certain proprietary broad-spectrum antiviral compounds for the treatment of coronavirus infections ("COVID-19").

    "We are pleased to be expanding our agreement with KSURF as we move forward with our ongoing COVID-19 development program. The additional compounds from this new license agreement represent a class of compounds called protease inhibitors to potentially treat COVID-19. The compounds are in a preclinical stage and have a novel mechanism of action that we believe could play an important role in treating this devastating disease," commented Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal.

    Cocrystal has been granted an exclusive, royalty-bearing right and license to certain small molecule therapeutic inhibitors against coronaviruses, picornaviruses and caliciviruses covered by patent rights controlled by KSURF. Cocrystal intends to pursue research and development of these antiviral compounds for coronavirus, including preclinical and clinical development. This license significantly expands and further advances the Company's COVID-19 program by providing more targeted, potent compounds for further development.

    The additional compounds licensed from KSURF have demonstrated both in vitro and in vivo activity in animal models against the viral pathogens MERS and SARS, which are coronaviruses that are structurally similar to SARS-CoV-2 (see About Coronavirus Disease below).

    "These new SARS-CoV-2 antiviral compounds have shown broad spectrum activity against SARS-CoV-2, SARS-CoV, and MERS-CoV and in vivo efficacy data in a MERS-CoV animal model that was recently used for in vivo study of remdesivir. We are encouraged that administration of this compound significantly increased survival and reduced lung virus titer in the infected animals even when given one day after virus infection. We are working tirelessly to leverage our proprietary drug discovery platform to advance this antiviral program and believe this new set of compounds has the potential to provide the lead compound for the program. As we progress our COVID-19 antiviral development program, we will continue to seek opportunities for collaboration with potential partners," commented Dr. Sam Lee, President of Cocrystal.

    Cocrystal's technology generates a 3-D structure of inhibitor complexes at near-atomic resolution providing the Company with the ability to identify novel binding sites, which allows for a rapid turnaround of structural information through highly automated X-ray data processing and refinement. By utilizing this technology, Cocrystal is able to develop compounds that specifically target enzymes that are essential for viral replication. The Company is currently leveraging its unique structure-based technologies to develop antiviral drugs for influenza viruses, hepatitis C viruses, coronaviruses and noroviruses.

    About Coronavirus Disease 2019 (COVID-19)

    COVID-19 is caused by a coronavirus called SARS-CoV-2. Coronaviruses are a large family of viruses that are common in people and many different species of animals, including camels, cattle, cats, and bats. Rarely, animal coronaviruses can infect people and then spread between people. This occurred with MERS-CoV and SARS-CoV, and now with the virus that causes COVID-19.

    The virus that causes COVID-19 is thought to spread mainly from person to person, mainly through respiratory droplets produced when an infected person coughs or sneezes. These droplets can land in the mouths or noses of people who are nearby or possibly be inhaled into the lungs. Spread is more likely when people are in close contact with one another (within about 6 feet).

    COVID-19 seems to be spreading easily and sustainably in the community ("community spread") in many affected geographic areas. Community spread means people have been infected with the virus in an area, including some who are not sure how or where they became infected.

    Summary updates are available on CDC's web page: Coronavirus Disease 2019 (COVID-19).

    About Cocrystal Pharma, Inc.

    Cocrystal Pharma, Inc. is a clinical stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza viruses, hepatitis C viruses, coronaviruses and noroviruses. Cocrystal employs unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. For further information about Cocrystal, please visit www.cocrystalpharma.com.

    Cautionary Note Regarding Forward-Looking Statements

    This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding our future research and development of antiviral compounds for COVID-19, including preclinical and clinical development, providing a lead compound for our COVID-19 program, and our plans regarding future collaborations. The words "believe," "may," "estimate," "continue," "anticipate," "intend," "should," "plan," "could," "target," "potential," "is likely," "will," "expect" and similar expressions, as they relate to us, are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events. Some or all of the events anticipated by these forward-looking statements may not occur. Important factors that could cause actual results to differ from those in the forward-looking statements include, but are not limited to, risks arising from the impact of the COVID-19 pandemic on our Company, including our ability to proceed with our programs, receive necessary regulatory approvals and continue to rely on certain third parties, and on the national and global economy, the results of preclinical and clinical studies, general risks arising from clinical trials, receipt of regulatory approvals, development of effective treatments and/or vaccines by competitors, and our ability to find and enter into agreements with suitable collaboration partners. Further information on our risk factors is contained in our filings with the SEC, including our Annual Report on Form 10-K for the year ended December 31, 2019. Any forward-looking statement made by us herein speaks only as of the date on which it is made. Factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. We undertake no obligation to publicly update any forward-looking statement, whether as a result of new information, future developments or otherwise, except as may be required by law.

    Investor and Media Contact:
    JTC Team, LLC
    (833) 475-8247

    ###

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  4. - Work completed over decades of renowned biochemist's career serves as basis for Company's structure-based technology which has demonstrated broad utility in development of proprietary antivirals -

    BOTHELL, WA, April 20, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today the appointment of Dr. Roger Kornberg to its Board of Directors. Dr. Kornberg has served as the Company's Chief Scientist and Chairman of our Scientific Advisory Board.

    Dr. Kornberg is a member of the U.S. National Academy of Sciences and the Winzer Professor of Medicine in the Department of Structural Biology at Stanford…

    - Work completed over decades of renowned biochemist's career serves as basis for Company's structure-based technology which has demonstrated broad utility in development of proprietary antivirals -

    BOTHELL, WA, April 20, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today the appointment of Dr. Roger Kornberg to its Board of Directors. Dr. Kornberg has served as the Company's Chief Scientist and Chairman of our Scientific Advisory Board.

    Dr. Kornberg is a member of the U.S. National Academy of Sciences and the Winzer Professor of Medicine in the Department of Structural Biology at Stanford University. He has been a member of the faculty of Stanford University since 1978.

    "Dr. Kornberg has been an integral part of Cocrystal for many years. His leadership and expertise while serving as our Chief Scientist and Chairman of our Scientific Advisory Board have been pivotal as we've advanced our pipeline of first- and best-in-class antiviral drugs. We are incredibly pleased to welcome him to our Board of Directors and to continue leveraging his knowledge and experience to identify and develop new antiviral compounds," commented Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal.

    In 2006, Dr. Kornberg was awarded the Nobel Prize in Chemistry in recognition for his studies of the molecular basis of Eukaryotic Transcription, the process by which DNA is copied to RNA. Dr. Kornberg is also the recipient of several awards, including the 2001 Welch Prize, the highest award granted in the field of chemistry in the United States, and the 2002 Leopald Mayer Prize, the highest award granted in the field of biomedical sciences from the French Academy of Sciences.

    Dr. Kornberg commented, "I am pleased to be strengthening my relationship with Cocrystal by joining the Company's Board of Directors at this exciting time. I strongly believe in the potential of the proprietary drug discovery platform technology and its utility in influenza, hepatitis C, COVID-19, and gastroenteritis. I continue to be encouraged by the positive data generated to date across this rich pipeline of development programs."

    About Cocrystal Pharma, Inc.

    Cocrystal Pharma, Inc. is a clinical stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza viruses, hepatitis C viruses, coronaviruses, and noroviruses. Cocrystal employs unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. For further information about Cocrystal, please visit www.cocrystalpharma.com.

    Investor and Media Contact:
    JTC Team, LLC
    (833) 475-8247

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  5. – Presentation with live audio webcast on Wednesday, April 22 at 11:00 AM ET, immediately followed by an interactive Q&A session –

    BOTHELL, WA,, April 15, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today that Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal will present at the April 2020 Virtual Investor Summit on Wednesday, April 22nd, 2020 at 11:00 AM ET.

    A live audio webcast of the presentation will be available on the IR Calendar page of the Investors section of the Company's website (cocrystalpharma.com). Immediately following the presentation, management will…

    – Presentation with live audio webcast on Wednesday, April 22 at 11:00 AM ET, immediately followed by an interactive Q&A session –

    BOTHELL, WA,, April 15, 2020 (GLOBE NEWSWIRE) -- Cocrystal Pharma, Inc. (NASDAQ: COCP), ("Cocrystal" or the "Company"), a clinical stage biotechnology company discovering and developing novel antiviral therapeutics, announced today that Dr. Gary Wilcox, Chairman and Chief Executive Officer of Cocrystal will present at the April 2020 Virtual Investor Summit on Wednesday, April 22nd, 2020 at 11:00 AM ET.

    A live audio webcast of the presentation will be available on the IR Calendar page of the Investors section of the Company's website (cocrystalpharma.com). Immediately following the presentation, management will participate in an interactive Q&A session with interested parties, allowing participants to type in questions and receive live responses. A webcast replay will be available two hours following the live presentation and will be accessible for 30 days.

    To schedule a one-on-one call with management, please contact the conference at and for more information, please visit virtualinvestorsummit.com.

    About Virtual Investor Summit

    The Virtual Investor Summit is an online platform that offers both public and private companies, across multiple industries the ability to stay active and engaged with the investment community. Our inaugural summit on April 22-23, 2020 will feature company webcast presentations followed by a virtual, interactive Q&A session, allowing participants to type in questions and receive live responses. Interested participants also have the ability to request one-on-one calls with a featured company. For more information, please visit virtualinvestorsummit.com.

    About Cocrystal Pharma, Inc.

    Cocrystal Pharma, Inc. is a clinical stage biotechnology company discovering and developing novel antiviral therapeutics that target the replication process of influenza viruses, hepatitis C viruses, noroviruses and coronaviruses. Cocrystal employs unique structure-based technologies and Nobel Prize winning expertise to create first- and best-in-class antiviral drugs. For further information about Cocrystal, please visit www.cocrystalpharma.com.

    Investor and Media Contact:
    JTC Team, LLC
    (833) 475-8247

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