AMTI Applied Molecular Transport Inc.

27.65
-1.1  -4%
Previous Close 28.75
Open 28.39
52 Week Low 20.5
52 Week High 78.22
Market Cap $1,058,396,212
Shares 38,278,344
Float 16,577,204
Enterprise Value $971,221,982
Volume 217,921
Av. Daily Volume 213,528
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Upcoming Catalysts

Drug Stage Catalyst Date
AMT-101 (LOMBARD)
Ulcerative colitis
Phase 2
Phase 2
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AMT-101 (CASTRO)
Rheumatoid arthritis
Phase 2
Phase 2
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AMT-101 (MARKET)
Ulcerative colitis
Phase 2
Phase 2
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AMT-101 (FILLMORE)
Pouchitis
Phase 2
Phase 2
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AMT-126
Healthy volunteers
Phase 1a
Phase 1a
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Latest News

  1. Once daily, oral AMT-101 was safe and well tolerated, and demonstrated trends of improvement in objective measures of inflammation: fecal calprotectin, CRP, and histology

    Key findings support oral AMT-101 actively exerts immunomodulatory effect resulting in local and systemic benefit

    Microbiome analyses demonstrate enhancement of favorable enteric commensal bacteria, correlated with restoration of intestinal immune homeostasis

    Company on track to announce oral AMT-101 top-line data readouts from the four Phase 2 trials, being conducted in multiple ulcerative colitis populations and rheumatoid arthritis, beginning in the second half of 2021 and into 2022

    SOUTH SAN FRANCISCO, Calif., July 09, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport…

    Once daily, oral AMT-101 was safe and well tolerated, and demonstrated trends of improvement in objective measures of inflammation: fecal calprotectin, CRP, and histology

    Key findings support oral AMT-101 actively exerts immunomodulatory effect resulting in local and systemic benefit

    Microbiome analyses demonstrate enhancement of favorable enteric commensal bacteria, correlated with restoration of intestinal immune homeostasis

    Company on track to announce oral AMT-101 top-line data readouts from the four Phase 2 trials, being conducted in multiple ulcerative colitis populations and rheumatoid arthritis, beginning in the second half of 2021 and into 2022

    SOUTH SAN FRANCISCO, Calif., July 09, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced additional Phase 1b data for oral AMT-101 in ulcerative colitis (UC) patients.   AMT-101 is a novel GI-selective, oral fusion of hIL-10 and AMT's proprietary carrier molecule. AMT presented the data in ePoster P294 AMT-101, a gut selective oral IL-10 fusion: results from a Phase 1b study in patients with active Ulcerative Colitis at the European Crohn's and Colitis Organisation (ECCO) ‘21 Virtual Congress.

    "Today's presentation highlighted important findings that support the use of once daily, oral AMT-101 in patients with active UC. We observed AMT-101 actively exerting an immunomodulatory effect by targeting lamina propria immune cells resulting in both local and systemic benefit," said Stefan Schreiber, M.D., University Hospital Schleswig-Holstein, Dep. Medicine, Kiel, Germany. "After only 14 days of treatment, potential clinical efficacy was observed at doses of 10mg or less with a reduction in average CRP and fecal calprotectin levels, enhancement of favorable enteric commensal bacteria and histological improvements in patients. Additionally, oral AMT-101 was safe and well tolerated without any AEs previously observed with systemic IL-10. As expected, with this gut-selective therapy, no systemic PK was detected."

    The Phase 1b multiple ascending dose trial evaluated safety and was a randomized, placebo-controlled 3:1, double-blind trial that included 16 patients with active ulcerative colitis. Patients received a 14-day treatment period of oral AMT-101 at 1, 3, 10, and 30mg doses.

    "These data further support advancement into our comprehensive Phase 2 development plan to explore oral AMT-101 in longer durations studies, for both IBD and RA," added Bittoo Kanwar M.D., chief medical officer. "As a result of the compelling Phase 1b findings presented today, we have strategically designed four global trials to potentially provide patients the greatest benefit and to generate data in monotherapy and combination regimens in both biologic-naïve and -experienced patient settings. We look forward to sharing topline data readouts for the four Phase 2 studies beginning in the second half of this year."

    About AMT-101

    AMT-101 is a novel GI-selective, oral fusion of hIL-10 and AMT's proprietary carrier molecule, and is currently being developed in four Phase 2 clinical trials in inflammatory bowel diseases and rheumatoid arthritis. AMT-101 is designed to cross the intestinal epithelial (IE) barrier with limited entry into the bloodstream, thereby focusing hIL-10 at the primary site of inflammation for UC and potentially avoiding the side effects observed with systemic administration. By design, AMT-101 is actively transported through the IE barrier into the GI tissue, the primary site of inflammation in UC.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform to design and develop a pipeline of novel oral biologic product candidates to treat autoimmune, inflammatory, metabolic, and other diseases. AMT's proprietary technology platform allows it to exploit existing natural cellular trafficking pathways to facilitate the active transport of diverse therapeutic modalities across the intestinal epithelial (IE) barrier. Active transport is an efficient mechanism that uses the cell's own machinery to transport materials across the IE barrier. AMT believes that its ability to exploit this mechanism is a key differentiator of its approach. AMT is developing additional oral biologic product candidates in patient-friendly oral forms that are designed to either target local intestinal tissue or enter systemic circulation to precisely address the relevant biology of a disease.

    AMT's headquarters, internal GMP manufacturing and lab facilities are located in South San Francisco, CA. For additional information on AMT, please visit www.appliedmt.com.

    Forward-Looking Statements

    This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Forward-looking statements generally relate to future events or AMT's future plans, strategy and performance. Such statements include, but are not limited to, the potential of, and expectations regarding the potential of, potential benefits of, and expectations regarding AMT's technology platform and AMT-101, statements regarding AMT's Phase 2 clinical trials for AMT-101 including the timing of such trials, expectations relating to data readouts from the Phase 2 clinical trials, and AMT's ability to leverage its technology to expand its pipeline. Such statements are subject to numerous important factors, risks and uncertainties that may cause actual events or results to differ materially, including those more fully described under the section entitled "Risk Factors" in documents the company files from time to time with the Securities and Exchange Commission. These forward-looking statements are made as of the date of this press release, and AMT assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law.

    Investor Relations Contact:

    Andrew Chang

    Head, Investor Relations & Corporate Communications

    Media Contacts:

    Alexandra Santos

    Wheelhouse Life Science Advisors

    Aljanae Reynolds

    Wheelhouse Life Science Advisors

     



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  2. SOUTH SAN FRANCISCO, Calif., June 09, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the JMP Securities Life Sciences Conference on Thursday, June 17, 2021 at 2:00 p.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology…

    SOUTH SAN FRANCISCO, Calif., June 09, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the JMP Securities Life Sciences Conference on Thursday, June 17, 2021 at 2:00 p.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform to design and develop a pipeline of novel oral biologic product candidates to treat autoimmune, inflammatory, metabolic, and other diseases. AMT's proprietary technology platform allows it to exploit existing natural cellular trafficking pathways to facilitate the active transport of diverse therapeutic modalities across the intestinal epithelial (IE) barrier. Active transport is an efficient mechanism that uses the cell's own machinery to transport materials across the IE barrier. AMT believes that its ability to exploit this mechanism is a key differentiator of its approach. AMT is developing additional oral biologic product candidates in patient-friendly oral forms that are designed to either target local gastrointestinal tissue or enter systemic circulation to precisely address the relevant biology of a disease.

    AMT's headquarters, internal GMP manufacturing and lab facilities are located in South San Francisco, CA. For additional information on AMT, please visit www.appliedmt.com

    Investor Relations Contact:

    Andrew Chang

    Head, Investor Relations & Corporate Communications

    Media Contacts:

    Alexandra Santos

    Wheelhouse Life Science Advisors

    Aljanae Reynolds

    Wheelhouse Life Science Advisors

     



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  3. SOUTH SAN FRANCISCO, Calif., May 26, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the Jefferies Virtual Healthcare Conference on Friday, June 4, 2021 at 11:00 a.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.
    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform…

    SOUTH SAN FRANCISCO, Calif., May 26, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the Jefferies Virtual Healthcare Conference on Friday, June 4, 2021 at 11:00 a.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform to design and develop a pipeline of novel oral biologic product candidates to treat autoimmune, inflammatory, metabolic, and other diseases. AMT's proprietary technology platform allows it to exploit existing natural cellular trafficking pathways to facilitate the active transport of diverse therapeutic modalities across the intestinal epithelial (IE) barrier. Active transport is an efficient mechanism that uses the cell's own machinery to transport materials across the IE barrier. AMT believes that its ability to exploit this mechanism is a key differentiator of its approach. AMT is developing additional oral biologic product candidates in patient-friendly oral forms that are designed to either target local gastrointestinal tissue or enter systemic circulation to precisely address the relevant biology of a disease.

    AMT's headquarters, internal GMP manufacturing and lab facilities are located in South San Francisco, CA. For additional information on AMT, please visit www.appliedmt.com.

    Investor Relations Contact:

    Andrew Chang

    Head, Investor Relations & Corporate Communications

    Media Contacts:

    Alexandra Santos

    Wheelhouse Life Science Advisors

    Aljanae Reynolds

    Wheelhouse Life Science Advisors



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  4. Enrollment ongoing in each of oral AMT-101's four Phase 2 trials

    On track to announce oral AMT-101 top-line data readouts from the four Phase 2 trials, being conducted in multiple ulcerative colitis populations and rheumatoid arthritis, beginning in the second half of 2021 and into 2022

    Expanded clinical pipeline with second product candidate, AMT-126, an oral IL-22 fusion biologic therapy for diseases associated with intestinal epithelial barrier defects; Initiated Phase 1a trial in healthy volunteers

    Received acceptance to present full AMT-101 Phase 1b ulcerative colitis data at ECCO'21 Virtual Congress in July

    Strengthened balance sheet with successful follow-on offering in April

    SOUTH SAN FRANCISCO, Calif., May 13, 2021 (GLOBE NEWSWIRE…

    Enrollment ongoing in each of oral AMT-101's four Phase 2 trials

    On track to announce oral AMT-101 top-line data readouts from the four Phase 2 trials, being conducted in multiple ulcerative colitis populations and rheumatoid arthritis, beginning in the second half of 2021 and into 2022

    Expanded clinical pipeline with second product candidate, AMT-126, an oral IL-22 fusion biologic therapy for diseases associated with intestinal epithelial barrier defects; Initiated Phase 1a trial in healthy volunteers

    Received acceptance to present full AMT-101 Phase 1b ulcerative colitis data at ECCO'21 Virtual Congress in July

    Strengthened balance sheet with successful follow-on offering in April

    SOUTH SAN FRANCISCO, Calif., May 13, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today provided a corporate update and reported financial results for the first quarter ended March 31, 2021.

    "Our proprietary technology platform and internal CMC capabilities have enabled AMT to generate differentiated novel oral biologics, and this broad platform continues to generate exciting pipeline opportunities," said Tahir Mahmood, Ph.D., chief executive officer and co-founder of AMT. "Following the initiation of our second clinical program, oral AMT-126, in a Phase 1a trial in healthy volunteers, we further strengthened our balance sheet with a successful follow-on offering in April. Importantly, these proceeds will enable AMT to optimize the development plan for oral AMT-126 and our next pipeline programs as they advance towards the clinic. We continue to believe that our most advanced programs, AMT-101 and AMT-126, have broad potential for targeting intestinal and systemic inflammatory indications and other diseases. With topline readouts from the four Phase 2 trials beginning in the second half of the year, we expect the next twelve to eighteen months to be a data-rich period for the company."

    Recent Business Highlights

    • Initiated Phase 2 trials for oral AMT-101:
      • MARKET combination trial of oral AMT-101 with anti-TNFα in biologic-naïve patients with moderate-to-severe ulcerative colitis (UC)
      • FILLMORE monotherapy trial for patients with chronic pouchitis
      • CASTRO combination trial of oral AMT-101 with anti-TNFα for patients with rheumatoid arthritis who are partial or non-responders to anti-TNFα therapy
    • Expanded clinical pipeline with second wholly internally-developed biologic therapeutic, AMT-126, a GI-selective oral fusion of IL-22 and our proprietary carrier molecule, for diseases associated with intestinal epithelial barrier defects; Initiated Phase 1a trial in healthy volunteers and expect the full Phase 1 development plan to resemble our AMT-101 approach; Expect to conduct a Phase 1b trial in patients with impaired intestinal epithelial barrier function.
    • Closed an underwritten public offering in April of 2,875,000 shares of our common stock, at a public offering price of $42.00 per share, resulting in net proceeds of approximately $112.9 million. Cash, cash equivalents, and investments as of March 31, 2021 pro-forma for the public offering were approximately $229.1M.
    • Successfully manufactured oral AMT-101 and AMT-126 GMP biologics at AMT's internal manufacturing facility
    • Received acceptance for our submission to present the full AMT-101 Phase 1b multiple ascending dose UC data set at the ECCO'21 Virtual Congress in July 2021
    • Strengthened the executive leadership team with key new hires, including Douglas Rich, chief technical officer, and Earl Douglas, executive vice president and general counsel

    Anticipated Upcoming Milestones

    • Top-line data readouts from the four oral AMT-101 Phase 2 trials beginning in 2H 2021 and into 2022
    • Top-line oral AMT-126 Phase 1a/b data in healthy volunteers and patients in 2022

    Financial Results for the First Quarter Ended March 31, 2021

    Research and development (R&D) expenses. Total R&D expenses for the first quarter of 2021 were $14.9 million, compared to $13.0 million for the same period in 2020. The increase was primarily due to higher expenses associated with clinical trials, preclinical studies, compensation and facilities related expenses, offset by a decrease in materials and contract manufacturing.

    General and administrative (G&A) expenses. Total G&A expenses for the first quarter of 2021 were $5.6 million, compared to $2.5 million for the same period in 2020. The increase was primarily due to an increase of $1.9 million in personnel and administrative costs due to an increase in headcount and an increase of $1.1 million in professional fees.

    Net loss. Net loss for the first quarter of 2021 was $20.5 million, compared to $15.3 million for the same period in 2020.

    Cash, cash equivalents, and investments. As of March 31, 2021, cash, cash equivalents, and investments were $108.3 million.

    About AMT-101

    AMT-101 is a novel GI-selective, oral fusion of hIL-10 and AMT's proprietary carrier molecule, and is currently being developed in four Phase 2 clinical trials in inflammatory bowel diseases and rheumatoid arthritis. AMT-101 is designed to cross the intestinal epithelial (IE) barrier with limited entry into the bloodstream, thereby focusing hIL-10 at the primary site of inflammation for UC and potentially avoiding the side effects observed with systemic administration. By design, AMT-101 is actively transported through the IE barrier into the GI tissue, the primary site of inflammation in UC.

    About AMT-126

    AMT-126 is a novel GI-selective, oral fusion of hIL-22 and AMT's proprietary carrier molecule currently in development for diseases related to IE barrier defects. IL-22 is a cytokine that repairs structural and functional defects of the IE barrier and induces microbial defense. AMT-126 is designed to act locally on the epithelial cells of the intestinal tissue, thereby repairing the IE barrier and supporting mucosal healing, potentially translating into clinically meaningful improvements in a broad range of GI-focused, peripheral inflammatory and other diseases.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform to design and develop a pipeline of novel oral biologic product candidates to treat autoimmune, inflammatory, metabolic, and other diseases. AMT's proprietary technology platform allows it to exploit existing natural cellular trafficking pathways to facilitate the active transport of diverse therapeutic modalities across the intestinal epithelial (IE) barrier. Active transport is an efficient mechanism that uses the cell's own machinery to transport materials across the IE barrier. AMT believes that its ability to exploit this mechanism is a key differentiator of its approach. AMT is developing additional oral biologic product candidates in patient-friendly oral forms that are designed to either target local intestinal tissue or enter systemic circulation to precisely address the relevant biology of a disease.

    AMT's headquarters, internal GMP manufacturing and lab facilities are located in South San Francisco, CA. For additional information on AMT, please visit www.appliedmt.com.

    Forward-Looking Statements

    This press release contains forward-looking statements as that term is defined in Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such forward-looking statements involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements including statements relating to AMT's plans, expectations, forecasts and future events. Such forward-looking statements include, but are not limited to, the potential of, and expectations regarding AMT's technology platform and AMT's internal manufacturing capabilities, statements regarding the optimization of our product development plans or the design of future clinical trials, statements regarding the potential of AMT-101 and AMT-126 or regarding AMT-101 and AMT-126 clinical trials, including the timing of data readouts from such trials and our ability to replicate past clinical development strategies, statements regarding the potential for AMT's product candidates to treat or provide clinically meaningful outcomes for certain medical conditions or diseases, and assumptions regarding the biological mode of action of our product candidates and the potential to avoid side effects with our product candidates. In some cases, you can identify forward-looking statements by terminology such as "estimate," "intend," "may," "plan," "potentially," "will," "expect," "enable" or the negative of these terms or other similar expressions. We have based these forward-looking statements largely on our current expectations and projections about future events and trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. Actual events, trends or results could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements based on various factors. Information regarding the foregoing and additional risks may be found in the section entitled "Risk Factors" in AMT's Annual and Quarterly Reports on Form 10-K and 10-Q filed with the Securities and Exchange Commission (the "SEC"), and AMT's future reports to be filed with the SEC. These forward-looking statements are made as of the date of this press release, and AMT assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law.



    Applied Molecular Transport Inc.

    Balance Sheets

    (in thousands, except share and per share amounts)

      March 31,  December 31, 
      2021  2020 
    Assets        
    Current assets:        
    Cash and cash equivalents $26,202  $5,843 
    Short-term investments  82,063   124,026 
    Prepaid expenses  2,648   1,311 
    Deferred offering costs  659    
    Other current assets  393   321 
    Total current assets  111,965   131,501 
    Property and equipment, net  6,999   8,447 
    Operating lease right-of-use assets, net  5,450    
    Finance lease right-of-use assets, net  796    
    Restricted cash  1,025   108 
    Other assets  169   127 
    Total assets $126,404  $140,183 
    Liabilities and stockholders' equity        
    Current liabilities:        
    Accounts payable $2,208  $3,174 
    Accrued expenses  4,094   4,173 
    Operating lease liabilities, current  2,377    
    Finance lease liabilities, current  235    
    Deferred rent, current     83 
    Capital lease obligations, current     232 
    Total current liabilities  8,914   7,662 
    Operating lease liabilities  3,589    
    Finance lease liabilities  344    
    Deferred rent     444 
    Capital lease obligations     404 
    Total liabilities  12,847   8,510 
    Commitments and contingencies (Note 6)        
    Stockholders' equity:        
    Common stock, $0.0001 par value, 450,000,000 shares authorized as of March 31, 2021 and December 31, 2020; 35,250,650 and 35,121,360 shares issued and outstanding as of March 31, 2021 and December 31, 2020, respectively  4   4 
    Additional paid-in capital  273,348   271,000 
    Accumulated other comprehensive income  25   27 
    Accumulated deficit  (159,820)  (139,358)
    Total stockholders' equity  113,557   131,673 
    Total liabilities and stockholders' equity $126,404  $140,183 
             



    Applied Molecular Transport Inc.

    Statements of Operations and Comprehensive Loss

    (in thousands, except share and per share amounts)

      Three Months Ended 
      March 31, 
      2021  2020 
    Operating expenses:        
    Research and development $14,881  $12,954 
    General and administrative  5,599   2,489 
    Total operating expenses  20,480   15,443 
    Loss from operations  (20,480)  (15,443)
    Interest income, net  40   83 
    Other (expense) income, net  (22)  49 
    Net loss $(20,462) $(15,311)
    Net loss per share, basic and diluted $(0.58) $(2.06)
    Weighted-average shares of common stock outstanding, basic and diluted  35,217,773   7,417,440 
    Comprehensive loss:        
    Net loss $(20,462) $(15,311)
    Other comprehensive (loss) income:        
    Unrealized (loss) gain on investments  (2)  6 
    Total comprehensive loss $(20,464) $(15,305)
             

    Refer to the Company's applicable SEC filings for previously reported periods.

    Investor Relations Contact:

    Andrew Chang

    Head, Investor Relations & Corporate Communications

    Media Contacts:

    Alexandra Santos

    Wheelhouse Life Science Advisors

    Aljanae Reynolds

    Wheelhouse Life Science Advisors



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  5. SOUTH SAN FRANCISCO, Calif., May 06, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the BofA Securities 2021 Health Care Conference on Wednesday, May 12, 2021 at 2:00 p.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology…

    SOUTH SAN FRANCISCO, Calif., May 06, 2021 (GLOBE NEWSWIRE) -- Applied Molecular Transport Inc. (NASDAQ:AMTI) (AMT), a clinical-stage biopharmaceutical company, today announced that Tahir Mahmood, Ph.D., chief executive officer and co-founder, will participate in a fireside chat during the BofA Securities 2021 Health Care Conference on Wednesday, May 12, 2021 at 2:00 p.m. ET.

    A live webcast will be accessible via the Events page of the Applied Molecular Transport website at https://ir.appliedmt.com/news-events/events. An archived replay will be available for 30 days following the event.

    About Applied Molecular Transport Inc.

    Applied Molecular Transport Inc. is a clinical-stage biopharmaceutical company leveraging its proprietary technology platform to design and develop a pipeline of novel oral biologic product candidates to treat autoimmune, inflammatory, metabolic, and other diseases. AMT's proprietary technology platform allows it to exploit existing natural cellular trafficking pathways to facilitate the active transport of diverse therapeutic modalities across the intestinal epithelial (IE) barrier. Active transport is an efficient mechanism that uses the cell's own machinery to transport materials across the IE barrier. AMT believes that its ability to exploit this mechanism is a key differentiator of its approach. AMT is developing additional oral biologic product candidates in patient-friendly oral forms that are designed to either target local gastrointestinal tissue or enter systemic circulation to precisely address the relevant biology of a disease.

    AMT's headquarters, internal GMP manufacturing and lab facilities are located in South San Francisco, CA. For additional information on AMT, please visit www.appliedmt.com.

    Investor Relations Contact:

    Andrew Chang

    Head, Investor Relations & Corporate Communications

    Media Contacts:

    Alexandra Santos

    Wheelhouse Life Science Advisors

    Aljanae Reynolds

    Wheelhouse Life Science Advisors



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